Brain

A new model of obsessive-compulsive disorder (OCD) that mirrors both symptoms of the disease and the timing of its treatment in humans has been created by University of Chicago researchers, according to a new study.

Researchers already know that chronic misuse of alcohol can cause widespread damage to the brain. While previous studies examined cortical atrophy in individuals with alcoholism, none examined alcohol-associated atrophy using cortical thickness measurements to obtain a regional mapping of tissue loss across the full cortical surface. This study does so, finding that alcohol damage occurs in gradations: the more alcohol consumed, the greater the damage.

Chronic alcoholism is often associated with a disturbed gait and balance, likely caused by alcohol damage to neural systems. While some studies have suggested that abstinence can lead to partial recovery of gait and balance functions, questions remain about duration of abstinence and sample size. This study of both short- and long-term abstinence has found that alcoholics' gait and balance can continue to recover with long-term abstinence from alcohol but that deficits can persist, especially eyes-closed standing balance.

Watching children on the playground, we see them run, climb, slide, get up, and do it all again. While their movements are continuous, we language-users can easily divide them up and name each one. But what about people—babies—who don't yet have words? How do they make sense of a world in motion?

Researchers have identified promising new therapies for ependymoma, a rare tumor with few treatment options. St. Jude Children's Research Hospital investigators led the effort, which used a new, faster drug development system that combines the latest drug screening technology with the first accurate animal model of the tumor.

A group led by a University of British Columbia and Vancouver Coastal Health scientist has discovered a type of spinal cord cell that could function as a stem cell, with the ability to regenerate portions of the central nervous system in people with spinal cord injuries, multiple sclerosis or amyotrophic lateral sclerosis (Lou Gehrig's disease).

Although still a young field, research in "decision neuroscience" has exploded in the last decade, with scientists beginning to decipher what exactly is happening in our brains when we are making choices, whether big or small.

In fact, early findings suggest it is possible to parse out the complexity of thinking into its individual components, and in the process determine how they are integrated as we ponder and decide.

SEATTLE, WASH. — September 15, 2011 — The Allen Institute for Brain Science announced today the discovery of a new class of cells in the spinal cord that act like neural stem cells, offering a fresh avenue in the search for therapies to treat spinal cord injury and disease.

A new paper by a team of University of Notre Dame researchers that included Shahriar Mobashery, Jeffrey Peng, Brian Baker and their researchers Oleg Borbulevych, Malika Kumararasiri, Brian Wilson, Leticia Llarrull, Mijoon Lee, Dusan Hesek and Qicun Shi describes a unique process that is central to induction of antibiotic resistance in the problematic bacterium methicillin-resistant Staphylococcus aureus (MSRA).

Prof. Dr. Motoharu Yoshida and colleagues from Boston University investigated how the rhythmic activity of nerve cells supports spatial navigation. The research scientists showed that cells in the entorhinal cortex, which is important for spatial navigation, oscillate with individual frequencies. These frequencies depend on the position of the cells within the entorhinal cortex. "Up to now people believed that the frequency is modulated by the interaction with neurons in other brain regions", says Yoshida. "However, our data indicate that this may not be the case.

CHAMPAIGN, Ill. — A study of more than 400 children diagnosed with Attention Deficit Hyperactivity Disorder has found a link between the children's routine play settings and the severity of their symptoms, researchers report. Those who regularly play in outdoor settings with lots of green (grass and trees, for example) have milder ADHD symptoms than those who play indoors or in built outdoor environments, the researchers found. The association holds even when the researchers controlled for income and other variables.

Fluctuations of serotonin levels in the brain, which often occur when someone hasn't eaten or is stressed, affects brain regions that enable people to regulate anger, new research from the University of Cambridge has shown.

Although reduced serotonin levels have previously been implicated in aggression, this is the first study which has shown how this chemical helps regulate behaviour in the brain as well as why some individuals may be more prone to aggression. The research findings were published today, 15 September, in the journal Biological Psychiatry.

Although still a young field, research in "decision neuroscience" has exploded in the last decade, with scientists beginning to decipher what exactly is happening in our brains when we are making choices, whether big or small.

In fact, early findings suggest it is possible to parse out the complexity of thinking into its individual components, and in the process determine how they are integrated as we ponder and decide.

Recent PET-measurements in Turku, Finland, show that the GSM mobile phone electromagnetic field suppresses glucose metabolism in temporoparietal and anterior temporal areas of the hemisphere next to the antenna.

Seemingly simple animals such as the snail and squid have ransacked the genetic toolkit over the last half billion years to find different ways to build complex brains, nervous systems and shells, according to an international team of researchers, including a neuroscientist with the University of Florida Whitney Laboratory for Marine Bioscience.