Women with advanced ovarian cancer may benefit more from immunotherapy drug treatments if they are given straight after chemotherapy, according to a new study published in Clinical Cancer Research* today.
Researchers - funded by Cancer Research UK** and based at Queen Mary University London - examined samples from 60 women *** with ovarian cancer and found that chemotherapy given prior to surgery activates specialised immune cells called T cells within the tumour.
Exposure to a group of common pesticides, called dithiocarbamates, has long been associated with an increased risk of Parkinson's disease, although the mechanism by which the compounds exert their toxicity on the brain has not been completely understood. A new UCLA study sheds light on the toxicity of the compounds while also suggesting a strategy that may help protect against the disease.
Millions of people use free livestreaming websites to watch sports and other live events online, but this comes with a considerable security risk. Researchers from KU Leuven-iMinds (Belgium) and Stony Brook University have found that viewers are often exposed to malware infections, personal data theft, and scams. As much as 50% of the video overlay ads on free livestreaming websites are malicious.
In a large prospective study published online in the British Journal of Cancer*, researchers looked at the association between nut consumption and prostate cancer risk and mortality among 47,299 men in the Health Professionals Follow-up Study.
WEST LAFAYETTE, Ind. - A new type of electronic sensor that might be used to quickly detect and classify bacteria for medical diagnostics and food safety has passed a key hurdle by distinguishing between dead and living bacteria cells.
Nagoya, Japan - Domestic goats first appeared in the Fertile Crescent, in modern-day Iran and Turkey, around 10,000 years ago through domestication of the Bezoar wild goat. However, as this wild goat species is distributed across a large part of the Middle East, it is still unclear whether all domestic goats in this region descend from a single domestication event, or if multiple domestications occurred.
A new study into pythons and boas has for the first time found the two groups of snakes evolved independently to share similar traits, shedding new light on how the reptiles evolved.
Pythons and boas are two families that include the largest snakes in the world, like the reticulated python and the anaconda boa, which have been known to grow close to eight meters in length.
Six mating positions (amplexus modes) are known among the almost 7,000 species of frogs and toads found worldwide. However, the Bombay night frog (Nyctibatrachus humayuni), which is endemic to the Western Ghats Biodiversity hotspot of India, mates differently. In a new study, scientists have described a new (seventh) mode of amplexus -- now named as dorsal straddle.
Sophia Antipolis - June 14, 2016: Fifteen minutes of daily exercise is associated with a 22% lower risk of death and may be a reasonable target for older adults, reveals research presented today at the EuroPRevent 2016 meeting by Dr David Hupin, a physician in the Department of Clinical and Exercise Physiology, University Hospital of Saint-Etienne in Saint-Etienne, France.1
In an analysis that included nearly 30,000 overweight or obese adults, compared with placebo, orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide were each associated with achieving at least 5 percent weight loss at 52 weeks, and phentermine-topiramate and liraglutide were associated with the highest odds of achieving at least 5 percent weight loss, according to a study appearing in the June 14 issue of JAMA.
Prescription of long-acting opioids for chronic noncancer pain was associated with an increased risk of all-cause mortality, including deaths from causes other than overdose, compared with anticonvulsants or cyclic antidepressants, according to a study appearing in the June 14, 2016 issue of JAMA.
(Boston) -- To date, there are no methods that can quickly and accurately detect pathogens in blood to allow the diagnosis of systemic bloodstream infections that can lead to life-threatening sepsis. The standard of care for detecting such blood-borne infections is blood culture, but this takes days to complete, only identifies pathogens in less than 30% of patients with fulminant infections, and it is not able to detect toxic fragments of dead pathogens that also drive the exaggerated inflammatory reactions leading to sepsis.
Using genome sequencing, researchers from the University of British Columbia, along with colleagues at the Imperial College in London, now have the ability to determine when a tuberculosis (TB) outbreak is over.
A virus that infects major freshwater bacteria appears to use stolen bits of immune system DNA to highjack their hosts' immune response.
Microbiologists have discovered that the virus, Cyanophage N1, carries a DNA sequence--a CRISPR--that is generally used by bacteria to fight off viral infection.
The new and sixth volume of Research on Chrysomelidae consists of five research articles devoted to the latest findings about the amazing family of over 37,000 leaf beetle species from more than 2,500 genera.