Body

Weekly bouts of moderate aerobic exercise on a bike or treadmill, or a brisk walk, combined with some weightlifting, may cut down levels of fat in the liver by up to 40 percent in people with type 2 diabetes, a study by physical fitness experts at Johns Hopkins shows.

According to researchers, who will present their findings on Sept. 18 at the annual meeting of the American Association of Cardiovascular and Pulmonary Rehabilitation, in Indianapolis, high liver fat levels are common among people with type 2 diabetes and contribute to heart disease risk.

GBC has very poor prognosis. Conventional surgery is considered the most effective treatment, but many cases are inoperable at the time of diagnosis. More recently, chemotherapy has shown activity in gallbladder cancer. However, no generally accepted standard chemotherapy for advanced, non-resectable cancer of the gallbladder or biliary tree has yet been established. In addition, more and more people pay close attention to the research of Chinese medicine for prevention and treatment of cancer recently.

Taurine is a potent antioxidant with hepatoprotective effects. Organelle based changes in hepatocytes after taurine treatment in experimental liver fibrosis were searched systematically and organelle injury scores decreased were found to decrease significantly. Moreover, ultrastructural and histopathological scores in both groups were in strong correlation.

Los Baños, Philippines – Declining agricultural productivity and continued growing demand have brought the world food situation to a crossroads. Failure to act now through a wholesale reinvestment in agriculture—including research into improved technologies, infrastructure development, and training and education of agricultural scientists and trainers—could lead to a long-term crisis that makes the price spikes of 2008 seem a mere blip.

Halothane is a volatile anesthetic, which was first introduced to clinical practice in 1956. In Iran, halothane is being used as the main anesthetic in more than 80% of hospitals. Unfortunately, increasing numbers of HH are being reported in Iran.

A research article to be published on September 14, 2008 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Eghtesadi-Araghi Payam from Shariati Hospital of Iran studied HH in Iran and its associated risk factors.

Pancreatic cancer is the fifth most common cause of cancer death in Japan. The prognosis is extremely poor because it is difficult to detect this disease in the early stage and also the postoperative incidence of recurrence is still high, and we have not had any effective treatment for inoperable patients. Recently, the chemoradiotherapy has been regarded as one of the standard therapy for locally advanced pancreatic cancer and it has improved the survival and presented a clinical benefit.

An international study of almost 2,000 people in Brazil, India, Sri Lanka, Iran and China has shown that a low cost strategy to keep in contact with people who have previously attempted suicide, can reduce the risk of subsequent suicides.

Given that suicide is among the top three causes of deaths in 15 to 34-year-olds, the strategy has the potential to help reduce the economic and societal loss of young people in their most productive years of life.

Previous studies have shown the beneficial effect of rebamipide, a novel anti-ulcer drug, on experimental colitis. The permeabilities of rebamipide in different intestinal segments remained unknown.

Hepatic ischemia reperfusion injury remains a significant problem for hepatic surgical procedures and also remains a limitation of liver transplantation. It is important to reduce ischemia reperfusion injury. Oxygen free radicals, produced on reperfusion, play a critical role in the injury caused by ischemia-reperfusion. Reactive oxygen radicals lead to an inflammatory response and tissue damage by activating various mediators. It can also directly damage cellular components. Various agents, such as antioxidants and antiinflammatories, have been investigated to reduce the injury.

Three RND efflux systems had been identified in H pylori, namely hefABC, hefDEF, and hefGHI, each of which consisted of a translocase, an accessory protein. But the contribution of efflux proteins to antibiotic resistance is not well established. 27 putative translocases also had been identified in the H pylori 26695 genome, but only four putative H pylori OEPs or TolC homologs were identified. While they could not quantitate the operons expression levels of the efflux systems in multidrug resistance strains of H pylori.

Gastric carcinoma is one of the most frequent malignant tumors in the world. The gastric carcinoma cell with fibroblastic pattern which intracellular adhesion was decreased showed active mobility and invasiveness,which indicated that the EMT was placed. The TJ protein participated in EMT of tumors. Four transmembrane proteins of claudin family were essential component of TJ, but the effect of the TJ protein in the development of cancers was not clarified, especially the effect of claudin-1 expression transformation in gastric carcinomas.

Although suboptimal postoperative pain control is associated with cardiovascular, respiratory and gastrointestinal complications, many multimodal regimens for analgesia following major colorectal laparotomy provide inadequate pain relief. Continuous wound infusions of local anaesthetics are a promising development as an adjunct to existing multimodal postoperative analgesic regimens. There is a need for a focused, quantitative review of the evidence specific to colorectal laparotomy.

Take a kidney out of the body and it still knows how to filter toxins from the blood.

But all bets are off in the face of high blood pressure.

"How does the kidney know how to do it and why does it break in hypertension?" says Dr. Edward W. Inscho, physiologist in the Medical College of Georgia Schools of Medicine and Graduate Studies.

Unique nanostructures which respond to stimuli, such as pH, heat and light will pave the way for safer, greener and more efficient chemical reactors.

Being developed by a consortium of UK universities, the nanostructures can regulate reactions, momentum, and heat and mass transfer inside chemical reactors. This technology will provide a step change in reactor technology for the chemical, pharmaceutical and agrochemical industries.

Children's Hospital of Pittsburgh of UPMC researchers have identified cells that may play a key role in some forms of steroid-resistant asthma, a complication of the condition that makes treatment even more challenging.

The identification of a lineage of cells known as T Helper Type 17 (Th17) may help scientists in the development of new treatments that lead to better control of asthma, according to the study's senior author, Jay K. Kolls, MD, chief of the Division of Pediatric Pulmonary Medicine, Allergy and Immunology at Children's Hospital.