Santa Barbara, CA –The Bren School-based authors of a study published Jan. 20 in the journal PLoS ONE have observed toxicity to marine organisms resulting from exposure to a nanoparticle that had not previously been shown to be toxic under similar conditions.
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A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of Illinois at Chicago College of Medicine.
The cholesterol receptor offers a promising new target for anti-viral therapy, for which an approved drug may already exist, say the researchers, whose findings were reported online in advance of publication in Nature Medicine.
Research involving scientists at The University of Nottingham has taken us a step closer to breeding hardier crops that can better adapt to different environmental conditions and fight off attack from parasites.
In a paper published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS), the researchers have shown that they can alter root growth in the plant Arabidopsis thaliana, or thale cress, by controlling an important regulatory protein.
New Rochelle, NY, January 24, 2012—The time for commercial development of gene therapy has come. Patients with diseases treatable and curable with gene therapy deserve access to the technology, which has demonstrated both its effectiveness and feasibility, says James Wilson, MD, PhD, Editor-in-Chief of Human Gene Therapy in a provocative commentary and accompanying videocast.
Evidence of cardiovascular disease and diabetes risk is present in the blood of adolescents who consume a lot of fructose, a scenario that worsens in the face of excess belly fat, researchers report.
An analysis of 559 adolescents age 14-18 correlated high-fructose diets with higher blood pressure, fasting glucose, insulin resistance and inflammatory factors that contribute to heart and vascular disease.
HOUSTON - (Jan. 24, 2012) - The many factors that contribute to how cells communicate and function at the most basic level are still not fully understood, but researchers at Baylor College of Medicine have uncovered a mechanism that helps explain how intracellular membranes fuse, and in the process, created a new physiological membrane fusion model.
The findings appear in the current edition of the journal PLoS Biology.
As scientific researchers become evermore competitive for scarce funding, scientific journals are increasing efforts to identify submissions that plagiarize the work of others. Still, it may take years to identify and retract the plagiarized papers and give credit to the actual researchers.
PROVIDENCE, R.I. [Brown University] -- Since its discovery 150 years ago, scientists have puzzled over whether the winged dinosaur Archaeopteryx represents the missing link in birds' evolution to powered flight. Much of the debate has focused on the iconic creature's wings and the mystery of whether — and how well — it could fly.
PHILADELPHIA -- Glioblastoma, a lethal brain cancer, is one of the most resistant to available therapies and patients typically live approximately 15 months.
Previous research has focused on the activation of the apoptosis, or cell death, pathway using therapeutic agents such as tumor necrosis factor-related apoptosis-inducing ligand (TRAIL); however, the vast majority of these experiments have been stymied by resistance.
Scientists have traced the origin of the 'speed gene' in Thoroughbred racehorses back to a single British mare that lived in the United Kingdom around 300 years ago, according to findings published in the scientific journal Nature Communications.
The origin of the 'speed gene' (C type myostatin gene variant) was revealed by analysing DNA from hundreds of horses, including DNA extracted from the skeletal remains of 12 celebrated Thoroughbred stallions born between 1764 and 1930.
Division of labour is not only a defining feature of human societies but is also omnipresent among the building blocks of biological organisms and is considered a major theme of evolution. Theoretical Biologists Claus Rueffler and Joachim Hermisson from Vienna University in collaboration with Günter P. Wagner from Yale University identified necessary conditions under which division of labour is favoured by natural selection. The results of their study are published in the Proceedings of the National Academy of Sciences (PNAS).
Montreal January 24, 2012 – A saliva test used to diagnose the human immunodeficiency virus (HIV), is comparable in accuracy to the traditional blood test, according to a new study led by the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University. The meta-analysis, which compared studies worldwide, showed that the saliva HIV test, OraQuick HIV1/2, had the same accuracy as the blood test for high-risk populations. The test sensitivity was slightly reduced for low risk populations.
Organic chemists at the University of York have made a significant advance towards establishing the origin of the carbohydrates (sugars) that form the building blocks of life.
A team led by Dr Paul Clarke in the Department of Chemistry at York have re-created a process which could have occurred in the prebiotic world.
Working with colleagues at the University of Nottingham, they have made the first step towards showing how simple sugars –threose and erythrose—developed. The research is published in Organic & Biomolecular Chemistry.
After people with low-grade glioma, a type of brain cancer, undergo neurosurgery to remove the tumors, they face variable odds of survival — depending largely on how rapidly the cancer recurs. Even though their doctors monitor the tumor closely with sophisticated imaging, it is difficult to determine with certainty whether cancer has returned in a more malignant state that requires aggressive treatment.
Los Angeles, CA – Experts from the International Headache Society (IHS) have developed new recommendations for conduct of acute and preventive migraine clinical trials. The third edition of Migraine Clinical Trials Guidelines is now available in the IHS journal Cephalalgia, which is published by SAGE.
The new guidelines represent an expert consensus summary, and recommend a contemporary, standardized, and evidence-based approach to investigators conducting and reporting randomised, controlled migraine clinical trials.