NEW YORK (May 22, 2012) -- Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes cancer growth. Now, Weill Cornell Medical College researchers have found that in these cancer cells, the 3-D architecture of DNA, wrapped up in a little ball known as a chromatin, is warped in such a way that a switch has been thrown on thousands of genes, turning them on or off to promote abnormal, unchecked growth.
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CAMBRIDGE, Mass. (May 22, 2012) – Pushed to the brink of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began. As an integral part of this system, heat shock protein 90 (HSP90) has been shown to help malignant cells accommodate the genetic changes and profound disturbances in normal biology that occur in cancers.
BLOOMINGTON, Ind. -- Two popular MTV programs about teenage pregnancy -- "16 and Pregnant" and "Teen Mom" -- were met with national debate. Critics said the shows glamorized teenage pregnancy, while supporters said they discouraged it.
A new study by an Indiana University professor suggests they're both right.
The study, which will appear in the journal Sexuality & Culture, focused on female students because of the high dropout rate associated with pregnancy among this demographic.
ATS 2012, SAN FRANCISCO – A new study conducted by researchers from Boston University has found that sarcoidosis accounts for 25 percent of all deaths among women in the Black Women's Health Study who have the disease. The study is the largest epidemiologic study to date to specifically address mortality in black females with sarcoidosis.
Results of the study will be presented at the ATS 2012 International Conference in San Francisco.
Internet governance policy has rapidly risen from a relatively marginal issue for the United States' foreign policy establishment to a significant component of the country's international affairs and national security strategy, according to a new paper from Rice University's Baker Institute for Public Policy.
Rapid DNA sequencing may soon become a routine part of each individual's medical record, providing enormous information previously sequestered in the human genome's 3 billion nucleotide bases. This week's NEWSFOCUS section of the journal Science describes recent advances in sequencing technology.
PORTLAND, Ore. — Women who are unable to quit smoking during pregnancy can significantly improve the lung function of their newborns by taking Vitamin C daily, according to a new study at Oregon Health & Science University Doernbecher Children's Hospital.
It's quite common for a female song sparrow to stray from her breeding partner and mate with the male next door, but a new study shows that sleeping around can be costly.
The 20-year study, which is reported in The American Naturalist, found that offspring conceived outside sparrows' social pairs go on to have lower reproductive success than within-pair offspring. The findings throw a monkey wrench into theories about why ostensibly monogamous animals might be inclined to cheat.
DURHAM, N.C. – Antibodies that help to stop the HIV virus have been found in breast milk. Researchers at Duke University Medical Center isolated the antibodies from immune cells called B cells in the breast milk of infected mothers in Malawi, and showed that the B cells in breast milk can generate neutralizing antibodies that may inhibit the virus that causes AIDS.
San Diego, CA (May 22, 2012) — New research being presented at Digestive Disease Week® (DDW) looks at patient experiences with colorectal cancer screening and questions current screening guidelines. Worldwide, colorectal cancer is the second most common cancer in women and the third most common in men. Studies found that patients prefer colonscopy over computed tomography colonography, despite the former's more invasive nature, and highlight the importance of a patient's experience and role in the process of colonoscopy.
Biomedical engineers at UC Davis have developed a microfluidic chip to test for latent tuberculosis. They hope the test will be cheaper, faster and more reliable than current testing for the disease.
"Our assay is cheaper, reusable, and gives results in real time," said Ying Liu, a research specialist working with Professor Alexander Revzin in the UC Davis Department of Biomedical Engineering.
The team has already conducted testing of blood samples from patients in China and the United States.
Excess weight in pregnant women, both before pregnancy and gained during pregnancy, is the main predictor of whether mothers will have larger than average babies, which can result in increased risk of cesarean section or trauma during delivery, states a study published in CMAJ (Canadian Medical Association Journal).
Although many people take bee pollen as a health supplement, it can cause severe anaphylactic reactions. However, most people are unaware of the risks, states an article published in CMAJ (Canadian Medical Association Journal).
Large randomized controlled trials (RCTs) are critical for determining effectiveness of medical therapies, tests and procedures. Yet Canada provides scant support for these studies compared with other western countries, states an analysis in CMAJ (Canadian Medical Association Journal).
The enforcement of Law 42/2010, which extends the smoking ban to public places, has accompanied a progressive reduction in the percentage of smokers (from 40.3% to 35.3%) and in consumption amongst the working population. This decline applies to men and women of all ages and occupations.
SINC