Lynch Syndrome is a heritable genetic mutation that causes colorectal, endometrial and other cancers. A cooperative study that included the University of Colorado Cancer Center, published in this month's issue of the Journal of the National Cancer Institute, revises the risk of colorectal cancer down but other cancers up for women with Lynch Syndrome who have had endometrial cancer.
Body
Critically endangered leatherback sea turtle populations in the western Pacific Ocean may be losing their last foothold of survival on the beaches of Indonesia, according to a paper published today in the scientific journal Ecosphere by an international group of scientists.
Researchers from the State University of Papua Indonesia, NOAA Fisheries Service, University of Alabama at Birmingham and World Wildlife Fund Indonesia released a report today documenting the continued decline of leatherback sea turtle nesting in the western Pacific Ocean.
(SALT LAKE CITY)—An estimated 300,000 U.S. patients get surgical site infections every year, and while the causes are varied, a new University of Utah study suggests that some who get an infection can blame it partly on their genes.
The Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group assessed night vision in a cohort of 1,052 CAPT patients. The main purpose of CAPT, a National Eye Institute-sponsored multicenter randomized clinical trial conducted from 1999 to 2005, was to investigate whether low-intensity laser treatment could prevent vision loss in patients with early stage age-related macular degeneration (AMD).
PHILADELPHIA — An increasing body mass index was associated with a higher risk for colorectal cancer with a specific molecular characteristic, and inversely, physical activity was linked to a decreased risk for that same cancer, according to data published in Cancer Research, a journal of the American Association for Cancer Research.
ANN ARBOR, Mich. — New research from the University of Michigan Comprehensive Cancer Center finds that the protein HER2 plays a role even in breast cancers that would traditionally be categorized as HER2-negative – and that the drug Herceptin, which targets HER2, may have an even greater role for treating breast cancer and preventing its spread.
MINNEAPOLIS/ST. PAUL (February 26, 2013) – Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia (AML) patients will benefit or not benefit from one of the newest antileukemic agents.
Their study is published today in Clinical Cancer Research.
February 26, 2013, New York, N.Y. and San Diego, Calif. – Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell growth and drug resistance, they are discovering molecular pathways that might lead to new targeted therapies to potentially treat this deadly cancer.
Huntington's disease, also known as Huntington's chorea, is a hereditary brain disease causing movement disorders and dementia. In Germany, there are about 8,000 patients affected by Huntington's disease, with several hundred new cases arising every year. The disease usually manifests between the ages of 35 and 50. To date, it is incurable and inevitably leads to death. It is caused by a specific genetic defect: In the patient's DNA, which is the carrier of genetic information, there are multiple copies of a certain motif. "Repeats like this are also found in healthy people.
Researchers at The Johns Hopkins University and Yale University have discovered that a specialized receptor, normally found in the nose, is also in blood vessels throughout the body, sensing small molecules created by microbes that line mammalian intestines, and responding to these molecules by increasing blood pressure. The finding suggests that gut bacteria are an integral part of the body's complex system for maintaining a stable blood pressure.
A researcher at the University of Southampton, working as part of a team from the UK and USA, believes the global eradication of malaria could be achieved by individual countries eliminating the disease within their own borders and coordinating efforts regionally. The team's findings have been published in the journal Science.
Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments for inherited muscle, brain, bone and skin disorders.
Researchers have discovered that the proteins within this coating – known as the nuclear envelope – vary greatly between cells in different organs of the body.
This variation means that certain disease causing proteins will interact with the proteins in the protective seal to cause illness in some organs, but not others.
UNIVERSITY PARK, Pa. -- Afterschool programs seem to be most effective when their organization and implementation is supported by both organizational and community resources, according to Penn State human development researchers.
Using a tool to help bridge the gap between research and real life, the researchers evaluated an afterschool program called the Good Behavior Game.
New Haven, Conn. — In a paper published online Feb. 26 in the journal Nature Communications, a Yale University team and collaborators propose a way of predicting whether a given glass will be brittle or ductile — a desirable property typically associated with metals like steel or aluminum — and assert that any glass could have either quality.
Ductility refers to a material's plasticity, or its ability to change shape without breaking.
AMHERST, Mass. – Women who reported eating a diet rich in iron were 30 to 40 percent less likely to develop pre-menstrual syndrome (PMS) than women who consumed lower amounts, in a study reported this week by researchers at the University of Massachusetts Amherst School of Public Health and Health Sciences and Harvard. It is one of the first to evaluate whether dietary mineral intake is associated with PMS development.