HOUSTON -- (March 13, 2013) – Few things in life are inevitable – death, taxes, and, if you live long enough, osteoarthritis.
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Christopher Cameron of the University of Montreal's Department of Biological Sciences and his colleagues have unearthed a major scientific discovery - a strange phallus-shaped creature they found in Canada's Burgess Shale fossil beds, located in Yoho National Park. The fossils were found in an area of shale beds that are 505 million years old.
Canada's 505 million year-old Burgess Shale fossil beds, located in Yoho National Park, have yielded yet another major scientific discovery – this time with the unearthing of a strange phallus-shaped creature.
BOSTON – March 13, 2013 – Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue of Nature, may lead to new therapies that increase BAT formation to treat obesity.
For the first time, researchers have mapped the genomes of tapeworms to reveal potential drug targets on which existing drugs could act. The genomes provide a new resource that offers faster ways to develop urgently needed and effective treatments for these debilitating diseases.
ORLANDO, Fla., March 13, 2013 – Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have determined the complete three-dimensional structure of a protein called HNF-4α. HNF-4α controls gene expression in the liver and pancreas, switching genes on or off as needed. People with mature onset diabetes of the young (MODY1), a rare form of the disease, have inherited mutations in the HNF-4α protein. This first-ever look at HNF-4α's full structure, published March 13 in Nature, uncovers new information about how it functions.
NEW YORK, MARCH 13, 2013 – Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer are buried inside cancer cells. Scientists from Memorial Sloan-Kettering Cancer Center and Eureka Therapeutics have collaborated to create the new human monoclonal antibody, which targets a protein associated with many types of cancer and is of great interest to cancer researchers.
KANSAS CITY, MO—A seemingly obscure gene in the female fruit fly that is only active in cells that will become eggs has led researchers at the Stowers Institute for Medical Research to the discovery of a atypical protein that lures, traps, and inactivates the powerful Polo kinase, widely considered the master regulator of cell division. Its human homolog, Polo-like kinase-1 (Plk1), is misregulated in many types of cancer.
KNOXVILLE—Despite overwhelming evidence about the benefits of physical activity for children, most American youngsters are not meeting the federal recommendation of 60 minutes a day.
A new study by a team of University of Tennessee researchers has identified specific ways—and estimated minutes for each approach—that can help children achieve the recommended daily physical activity goal.
SAN DIEGO – (March 13, 2013) A virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero development, 1 in 750 children are born with or develop permanent disabilities such as hearing loss or brain damage. But efforts to develop a first-ever CMV vaccine are gaining ground.
Following several years of study, investigators have found more evidence that viral therapy to treat solid tumors can be enhanced by blocking the body's natural immune response.
Younger doctors are more likely than older generations to train and work in the same region as their home before entering medical school. New research published in the Journal of the Royal Society of Medicine investigating the geographical mobility of UK-trained doctors, reveals that 36% attended a medical school in their home region. 34% of hospital consultants and GP partners settled in the same region as their home before entering medical school. The geographical distribution of doctors is an important factor in the equitable distribution of health services.
March 13, 2013, Shenzhen, China - In a collaborative study published online today in Nature Communications, researchers from Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, BGI-Shenzhen, and University of Arizona have completed the genome sequencing of wild rice Oryza brachyantha. This work provides new insights for researchers to understand the function and evolution of Oryza genomes.
Scientists are reporting an advance toward overcoming a major barrier to tapping the potential of traditional Chinese medicine (TCM) and India's Ayurvedic medicine in developing new and more effective modern drugs. Their report appears in ACS' Journal of Chemical Information and Modeling.
Scientists at Griffith University's Institute for Glycomics and The Saban Research Institute of Children's Hospital Los Angeles have discovered a critical weakness in leukaemic cells, which may pave the way to new treatments.
The research team has demonstrated that leukaemic cells can be eradicated by removing a carbohydrate modification displayed on the cell's surface.