National Science Foundation (NSF) Director Subra Suresh and National Commission for Scientific and Technological Research (CONICYT) President José Miguel Aguilera announced today a new research partnership with Chile through Graduate Research Opportunities Worldwide (GROW). The agreement was signed at the CONICYT headquarters in Santiago, Chile. GROW is a coordinated effort that enhances international collaborative research opportunities for NSF Graduate Research Fellows. There are now GROW agreements between NSF and science agencies in 10 countries.
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As success rates in treating childhood cancers have improved, greater emphasis is being placed on quality of life issues following successful treatment. Many cancer treatments can lead to infertility, but there are few methods to preserve the fertility of children who have not entered puberty. Spermatogonial stem cells (SSCs), which produce sperm cells, are present prior to the start of puberty.
Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers. In this issue of the Journal of Clinical Investigation, researchers led by Caroline Demangel at the Pasteur Institue in Paris investigated the molecular actions of mycolactone and found that it dysregulates the cellular skeleton (cytoskeleton) through activation of a protein known as N-WASP. They found that excessive N-WASP activity caused defects in cell adhesion and migration that impaired the integrity of the skin.
Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers.
In the Journal of Clinical Investigation, researchers led by Caroline Demangel at the Pasteur Institue in Paris investigated the molecular actions of mycolactone and found that it dysregulates the cellular skeleton (cytoskeleton) through activation of a protein known as N-WASP.
Today archaeologists unearthed a 'Black Death' grave in London, containing more than a dozen skeletons of people suspected to have died from the plague. The victims are thought to have died during the 14th century and archaeologists anticipate finding many more as they excavate the site.
The genome of an extinct Australian frog has been revived and reactivated by a team of scientists using sophisticated cloning technology to implant a "dead" cell nucleus into a fresh egg from another frog species.
The bizarre gastric-brooding frog, Rheobatrachus silus – which uniquely swallowed its eggs, brooded its young in its stomach and gave birth through its mouth - became extinct in 1983.
Athens, Ga. – Students who date in middle school have significantly worse study skills, are four times more likely to drop out of school and report twice as much alcohol, tobacco and marijuana use than their single classmates, according to new research from the University of Georgia.
"Romantic relationships are a hallmark of adolescence, but very few studies have examined how adolescents differ in the development of these relationships," said Pamela Orpinas, study author and professor in the College of Public Health and head of the Department of Health Promotion and Behavior.
In their experiment the researchers used a carbon nanotube that was mounted between two metal electrodes, spanned a distance of about 1 µm, and could vibrate mechanically. Then, they applied an organic molecule with a magnetic spin due to an incorporated metal atom. This spin was oriented in an external magnetic field.
Scientists at Johannes Gutenberg University Mainz (JGU) and the Max Planck Institute for Polymer Research (MPI-P) in Germany have created a new synthetic hybrid material with a mineral content of almost 90 percent, yet extremely flexible. They imitated the structural elements found in most sea sponges and recreated the sponge spicules using the natural mineral calcium carbonate and a protein of the sponge. Natural minerals are usually very hard and prickly, as fragile as porcelain.
SAN DIEGO - Telestroke programs substantially improve access to life-saving stroke care, extending coverage to less populated areas in an effort to reduce disparities in stroke care access. A new study by researchers from the Perelman School of Medicine at the University of Pennsylvania, being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013, found that telemedicine programs in Oregon pushed stroke coverage into previously uncovered, less populated areas and expanded coverage by approximately 40 percent.
SAN DIEGO – Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013.
Humans aren't the only species with a sweet tooth. Research from North Carolina State University shows that the invasive spotted-wing vinegar fly (Drosophila suzukii) also prefers sweet, soft fruit – giving us new insight into a species that has spread across the United States over the past four years and threatens to cause hundreds of millions of dollars in damage to U.S. fruit crops.
Highlights
Arnhem, 11 March 2013 - A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs).
Arnhem, 11 March 2013- A recent study conducted by a group of German scientists revealed the presence of a previously unknown cell in the urethra of mice. These chemosensory cholinergic brush cells are in close contact to sensory neurons that express cholinergic receptors.
The authors suggest that in analogy to brush cells of the respiratory tract, the urethral brush cells may also serve as sentinels being able to detecting hazardous substances and preventing their further retrograde ingression.