Body

From skeletons and biopsies, an international team of scientists was successful in reconstructing a dozen medieval and modern genomes of the leprosy-causing bacteria Mycobacterium leprae. Under the direction of Professor Johannes Krause, University of Tübingen, and Professor Stewart Cole, Swiss Federal Institute of Technology of Lausanne (EPFL), the research group created a genome from archaeological finds for the first time without having to resort to a reference sequence. Professor Almut Nebel and Dr.

They lie dormant for years, but at the first sign of favorable conditions they awaken. This sounds like the tagline for a science fiction movie, but it describes the amazing life-cycles of microbial organisms that form the biological soil crusts (BSCs) of Earth's deserts. Now a research team with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) has reported a unique molecular-level analysis of a BSC cyanobacterium responding to the wetting and drying of its environment.

The ocean the Titanic sailed through just over 100 years ago was very different from the one we swim in today. Global warming is increasing ocean temperatures and harming marine food webs. Nitrogen run-off from fertilizers is causing coastal dead zones. A McGill-led international research team has now completed the first global study of changes that occurred in a crucial component of ocean chemistry, the nitrogen cycle, at the end of the last ice age. The results of their study confirm that oceans are good at balancing the nitrogen cycle on a global scale.

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

In a piece of work carried out by the Carbohydrate Metabolism Research Team of the Institute of Agrobiotechnology (a centre jointly owned by the NUP/UPNA-Public University of Navarre, the Spanish National Scientific Research Council-CSIC, and the Government of Navarre), the discovery has been made of the way in which the glgS gene (now renamed as the "surface composition regulator", scoR) acts in bacteria and how the mechanisms involved in bacterial infection can be altered by manipulating this gene, which indirectly affects glycogen production.

Scientists who designed GPS tracking collars to study hunting cheetahs in Botswana have miniaturised them to track 50 domestic cats in a Surrey village for a BBC programme. The BBC also deployed cat-cams which were turned on by the collar's activity sensor when the cat was moving. 'The Secret Life of The Cat' is broadcast on BBC Two Horizon on Thursday June 13th 2013 at 21:00.

If you are healthy and plan to start running for the first time, it is perfectly all right to put on a pair of completely ordinary 'neutral' running shoes without any special support. Even though your feet overpronate when you run – i.e. roll inwards.

There appears to be no risk that overpronation or underpronation can lead to running injuries through using neutral shoes for this special group of healthy beginners.

Cold Spring Harbor, NY – By identifying a protein that acts as a genetic modifier, scientists at Cold Spring Harbor Laboratory (CSHL) have solved the mystery of why some infants are born with a grave syndrome consisting of cleft palate and major deformities of the skin and limbs, while other infants bearing the same predisposing genetic mutation bear little or no sign of the illness, called EEC.

Ottawa—June 14, 2013—Here's a good reason to pay attention in math class. Nature Communications has published a paper from Ottawa researchers today, outlining how advanced mathematical modelling can be used in the fight against cancer. The technique predicts how different treatments and genetic modifications might allow cancer-killing, oncolytic viruses to overcome the natural defences that cancer cells use to stave off viral infection.

A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the journal Cancer Research.

Metastasis is responsible for 90 percent of cancer-related deaths. More than 575,000 Americans die of cancer each year, the second leading cause of death in the United States after cardiovascular disease.

Staph infections in hospitals are a serious concern, so much so that the term Methicillin-resistant Staphylococcus aureus (MRSA) is as commonly known as MRI. Far less known is that in many of these cases, patients are infecting themselves.

In heart surgeries and knee and joint-replacement procedures, up to 85 percent of staph infections after surgery come from patients' own bacteria, according to a 2002 study in the New England Journal of Medicine.

Sponsors and researchers will be given one year to act before independent scientists begin publishing the results themselves using previously confidential trial documents.

The BMJ and PLOS Medicine have already endorsed the proposal and committed to publishing restorative clinical trial submissions - and will discuss it in more detail at a meeting in London on Friday 14 June 2013.

However, the authors stress that the overall risk of severe problems is small and the results are significant only for women who have previously given birth – not for first-time mums.

The relative safety of planned home births is a topic of continuous debate, but studies have so far been too small to compare severe maternal complications between planned home and planned hospital birth among low risk women.

Of all Western countries, the Netherlands has the highest percentage of home births, assisted by a primary care midwife.

A study published in this week's PLOS Computational Biology reports that menopause is an unintended outcome of natural selection caused by the preference of males for younger female mates. While conventional thinking has held that menopause prevents older women from continuing to reproduce, the researchers, from McMaster's University, concluded that it is the lack of reproduction that has given rise to menopause.

HAMILTON, ON, June 13, 2013 — After decades of laboring under other theories that never seemed to add up, a team led by biologist Rama Singh has concluded that what causes menopause in women is men.

Singh, an evolutionary geneticist, backed by computer models developed by colleagues Jonathan Stone and Richard Morton, has determined that menopause is actually an unintended outcome of natural selection – the result of its effects having become relaxed in older women.