The majority of children at risk of type 1 diabetes who developed 2 or more diabetes-related autoantibodies developed type 1 diabetes within 15 years, findings that highlight the need for research into finding interventions to stop the development of multiple islet autoantibodies, according to a study in the June 19 issue of JAMA.
Body
HOUSTON – Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.
A team led by scientists at The University of Texas MD Anderson Cancer Center reported the tie between epidermal growth factor receptor (EGFR), a well-known cancer drug target, and MCM7, a protein vital to the first step in DNA replication, in the June issue of Cancer Cell.
Glycoproteins are an essential part of our body: These sugar-protein hybrid molecules are what makes the protective mucus that lines our lungs and stomach. They are also part of the fluid that lubricates our joints, the synovial fluid, and cover all our cells, with the sugar parts, the glycans, sticking out like a tiny forest of antennae. Researchers in the Laboratory for Surface Science and Technology at ETH Zurich and the Laboratories of Nanoscale Materials Science of Empa have identified a surprising effect that glycans have on the water molecules that surround them.
Swainson' s Thrushes, from a local population near Bolinas, CA spend their winters together in Mexico, according to a new tracking study released by Point Blue Conservation Science, (Point Blue, formerly PRBO). This result is important because it shows that the conservation of habitat for these local populations in California is tightly linked with climate and habitat changes in Mexico, where these birds spend their winters, 1,600 miles away.
It's not a hacker lab. At Brandeis University, sophisticated computational models and advances in graphical processing units are helping scientists understand the complex interplay between genomic data, virus structure and the formation of the virus' outer "shell" — critical for replication.
"We hope that some of what we are finding will help researchers alter virus assembly, leaving viruses unable to replicate," says post-doctoral fellow Jason Perlmutter, first author of the scientific paper describing the technique, published in the open access journal eLife.
A research team led by UCSF scientists has found that exposure in infancy to nitrogen dioxide (NO2), a component of motor vehicle air pollution, is strongly linked with later development of childhood asthma among African Americans and Latinos.
The researchers said their findings indicate that air pollution might, in fact, be a cause of the disease, and they called for a tightening of U.S government standards for annual exposure to NO2.
DURHAM, N.C. -- Anyone who has ever owned a pet will tell you that it has a unique personality.
Yet only in the last 10 years has the study of animal personality started to gain ground with behavioral ecologists, said Jennifer Verdolin of the National Evolutionary Synthesis Center, in Durham, NC.
She and a colleague have now found distinct personalities in the grey mouse lemur (Microcebus murinus), the tiny, saucer-eyed primate native to the African island of Madagascar.
SAN FRANCISCO – (June 18, 2013) – Men who lose sleep during the work week may be able to lower their risk of developing Type 2 diabetes by getting more hours of sleep, according to Los Angeles Biomedical Research Institute (LA BioMed) research findings presented today at The Endocrine Society's 95th Annual Meeting in San Francisco.
Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of breast cancer, researchers from the University of Chicago report in the July 2013 issue of the journal Cancer Prevention Research.
Hormonal therapy for transsexual patients is safe and effective, a multicenter European study indicates. The results will be presented Saturday at The Endocrine Society's 95th Annual Meeting in San Francisco.
Transsexual individuals who seek treatment may feel as though they were born the wrong gender. Surgical and hormonal therapies are available to help these people change their external characteristics to match their internal image of themselves.
Similar genetic variations occur in both overweight newborns and obese adults, a large study finds. The results will be presented Tuesday at The Endocrine Society's 95th Annual Meeting in San Francisco.
Taking calcium and vitamin D before exercise may influence how bones adapt to exercise, according to a new study. The results will be presented on Tuesday at The Endocrine Society's 95th Annual Meeting in San Francisco.
Researchers have developed a risk assessment scoring system that they believe may better identify certain adults-– especially African Americans-– at high risk of developing type 2 diabetes, heart disease and stroke than does the current system of diagnosing the metabolic syndrome. The results will be presented Tuesday at The Endocrine Society's 95th Annual Meeting in San Francisco.
NEW YORK (June 18, 2013)-- An international team of investigators co-led by Weill Cornell Medical College is offering a new framework for evidence-based surgery and device research, similar to the kind of risk and benefit analysis used in evidence-based medicine.
"Currently, there is no dynamic research framework to systematically detect devices and surgeries that don't offer any benefits to patients or may even be harmful," says co-lead investigator Dr. Art Sedrakyan of Weill Cornell Medical College.
A new study confirms directly what scientists previously knew only indirectly: The poisonous "rotten egg" gas hydrogen sulfide is generated by our body's growing cells.
Hydrogen sulfide, or H2S, is normally toxic, but in small amounts it plays a role in cardiovascular health.
In the new study, chemists developed a chemical probe that reacts and lights up when live human cells generate hydrogen sulfide, says chemist Alexander R. Lippert, Southern Methodist University, Dallas. The discovery allows researchers to observe the process through a microscope.