Body

This may be because family doctors tend to attribute women's - rather than men's - initial symptoms to harmless causes, such as bacterial infections, and some women therefore have to visit their GP several times before they get referred to a specialist, say the researchers.

Currently, survival rates for kidney and bladder cancer in England show that fewer women than men live for five years after diagnosis.

PITTSBURGH—A landmark study investigating the long-term effects of weight loss on the risks of cardiovascular disease among patients with Type 2 diabetes has now concluded, with significant results to be published today in the New England Journal of Medicine.

Postmenopausal hormone therapy with conjugated equine estrogens (CEEs) was not associated with overall sustained benefit or risk to cognitive function when given to women ages 50 to 55 years, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

The Women's Health Initiative Memory Study (WHIMS) demonstrated that postmenopausal hormone therapy with CEEs, when prescribed to women 65 years and older, caused deficits in global and domain-specific cognitive functioning.

Hospital performance on publicly reported conditions (acute myocardial infarction [heart attack], congestive heart failure, and pneumonia), may potentially be used as a signal of overall hospital mortality rates, according to a study by Marta L. McCrum, M.D., of Harvard School of Public Health, Boston, and colleagues. (Online First)

Conversations between parents and adolescents that focus on weight and size are associated with an increased risk for unhealthy adolescent weight-control behaviors, according to a study published Online First by JAMA Pediatrics, a JAMA Network publication.

The study by University of Minnesota, Minneapolis, researchers also found that overweight or obese adolescents whose mothers engaged in conversations that were focused only on healthful eating behaviors were less likely to diet and use unhealthy weight-control behaviors (UWCBs).

The excess risk of death from ischemic (due to reduced blood flow), but not hemorrhagic (due to bleeding), stroke in US black children has decreased over the past decade, according to a study by Laura L. Lehman, M.D., of Boston Children's Hospital, and colleagues. (Online First)

EAST BOOTHBAY, MAINE -- A research team led by Bigelow Laboratory for Ocean Sciences has discovered that marine microbes are adapted to very narrow and specialized niches in their environment. This may explain why so few of these microbes—usually less than 1%—can be grown for study in the laboratory. By utilizing new genetic tools, the researchers' new ability to read and interpret genetic information from the remaining 99% will be pivotal in detecting and mitigating the impact of human activities in the ocean.

Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, scientists have found.

The researchers, affiliated with the University of Maryland School of Medicine's Institute for Genome Sciences, analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and The Cancer Genome Atlas.

They considered the phenomenon of lateral gene transfer (LGT), the transmission of genetic material between organisms in a manner other than than traditional reproduction.

ROCHESTER, Minn. -- Rural women with breast cancer are less likely than their urban counterparts to receive recommended radiation therapy after having a lumpectomy, a breast-sparing surgery that removes only tumors and surrounding tissue, a study by Mayo Clinic and others found. The difference is one of several rural disparities in breast cancer diagnosis and treatment the researchers discovered. The findings are being presented at the AcademyHealth Annual Research Meeting in Baltimore.

DEERFIELD, IL—During the Permian era, the Earth was dominated by a single supercontinent called Pangea – "All-Earth". Animal and plant life dispersed broadly across this land, as documented by identical fossil species found on multiple modern continents. But a new study published in the Journal of Vertebrate Paleontology supports the idea that there was an isolated desert in the middle of Pangea with a fauna all its own.

CHAMPAIGN, Ill. — Researchers say they now know what allows some Western corn rootworms to survive crop rotation, a farming practice that once effectively managed the rootworm pests. The answer to the decades-long mystery of rotation-resistant rootworms lies – in large part – in the rootworm gut, the team reports.

The findings appear in the Proceedings of the National Academy of Sciences.

PROVIDENCE, R.I. [Brown University] —When working a cold case, smart investigators try something new. By taking a novel approach to nuclear magnetic resonance spectroscopy – a blending of four techniques – scientists have been able to resolve a key interaction between two proteins that could never be observed before. They report on their findings the week of June 24, 2013 in Proceedings of the National Academy of Sciences (PNAS).

Planktonic bacteria inhabiting the world's oceans have streamlined their genetic makeup to become lean, mean survival machines, according to new research by an international team of researchers, including microbiologists at the University of British Columbia.

The findings, published this week in the Proceedings of the National Academy of Sciences, is the first direct evidence of widespread genome reduction--organisms evolving to cast off superfluous genes and traits in favor of simpler, specialized genetic make-ups optimized for rapid growth.

Evolution, it seems, sometimes jumps instead of crawls.

A research team led by a University of Chicago scientist has discovered two key mutations that sparked a hormonal revolution 500 million years ago.

CAMBRIDGE, Mass. — Nanoparticles that deliver short strands of RNA offer a way to treat cancer and other diseases by shutting off malfunctioning genes. Although this approach has shown some promise, scientists are still not sure exactly what happens to the nanoparticles once they get inside their target cells.

A new study from MIT sheds light on the nanoparticles' fate and suggests new ways to maximize delivery of the RNA strands they are carrying, known as short interfering RNA (siRNA).