- A novel drug called Bendavia can help prevent acute kidney injury in animal models and is currently being studied in clinical trials for kidney disease.
- Bendavia acts by protecting a unique compound called cardiolipin, which is only found in mitochondria and is essential for keeping cells alive and functioning.
- Acute kidney injury has more than doubled since 2000, causing nearly 39,000 deaths in 2009.
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Irvine, Calif. — Giving the phrase "Mother knows best" a whole new meaning, UC Irvine researchers have identified unique genes in female butterflies that enable them to select the best host plant for their larvae – and avoid deadly ones.
"Ocean predator" conjures up images of sharks and barracudas, but the voracious red lionfish is out-eating them all in the Caribbean – and Mother Nature appears unable to control its impact on local reef fish. That leaves human intervention as the most promising solution to the problem of this highly invasive species, said researchers at the University of North Carolina at Chapel Hill.
CINCINNATI—A recently discovered form of the protein that triggers blood clotting plays a critical role in promoting the growth of metastatic pancreatic cancer and primary breast cancer, according to the cumulative findings from two new scientific manuscripts published online ahead of print in the International Journal of Cancer and PNAS (Proceedings of the National Academy of Sciences).
CORVALLIS, Ore. – Last month, the first expedition to use a deep-diving submersible to study the Atlantic Ocean lionfish invasion found something very disturbing – at 300 feet deep, there were still significant populations of these predatory fish, and they were big.
Using the same type of mathematical formulas used to draw political redistricting maps, Johns Hopkins researchers say they have developed a model that would allow for the more equitable allocation of livers from deceased donors for transplantation.
July 11, 2013 — (Bronx, NY) —Researchers at Albert Einstein College of Medicine of Yeshiva University have found that nerves play a critical role in both the development and spread of prostate tumors. Their findings, using both a mouse model and human prostate tissue, may lead to new ways to predict the aggressiveness of prostate cancer and to novel therapies for preventing and treating the disease. The study published online today in the July 12 edition of Science.
The AIDS virus can be used to treat two severe hereditary diseases. After an Italian scientist's "stroke of genius" in 1996, and after years of promising results in the laboratory, double official recognition by one of the most important international scientific journals has now arrived. And six children from all over the world, after three years of treatment, are well and show significant benefits.
HOUSTON -- Two Houston researchers from Baylor College of Medicine and Texas Children's Hospital were part of an international team that developed a new gene therapy approach to treatment of Wiskott-Aldrich Syndrome, a fatal inherited form of immunodeficiency.
New Rochelle, NY, July 11, 2013—Mosquito-borne dengue viruses cause an estimated 50 million cases of human dengue fever a year and are a significant public health threat worldwide. A novel therapeutic approach prevents dengue virus from reproducing in humans by targeting and silencing key regions of the dengue genome essential for viral replication. This innovative treatment strategy and the successful results of initial testing are presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.
There are some combinations that just go well together: Milk and cookies, eggs and bacon, pancakes and maple syrup. But new research reveals that people with individualistic mindsets differ from their collectivist counterparts in ascribing value to those perfect combinations.
A Vanderbilt research program that trains community pediatricians to diagnose autism within their individual practices may lead to more effective treatment of the disorder that now affects an estimated one in 88 children.
Vanderbilt University Medical Center researchers released today in the journal Autism the results of a three-year study that evaluated the effectiveness of a training program designed to enhance autism spectrum disorder (ASD) identification and assessment within community pediatric settings across Tennessee.
[Geneva, Switzerland – 11 July 2013] – This week the World Health Organization (WHO) released its newly updated 4th WHO Model List of Essential Medicines for Children (EMLc), in which three treatments developed by the Drugs for Neglected Diseases initiative (DNDi) and its partners have now been included. One treatment was also added to the 18th WHO Model List of Essential Medicines (EML) for adults.
Cancer vaccines prime the immune system to attack cancer cells, decreasing tumor progression. IL-12p70, a molecule produced by certain types of immune cells, has been shown to reduce tumor progression, but delivering it as part of a cancer vaccine has been limited because of its toxicity in high doses. In the current issue of the Journal of Clinical Investigation, Dr. Beatriz Carreno and colleagues at Washington University report the results of a clinical trial that tested a vaccine to treat newly diagnosed advanced melanoma.
"By comparing identical tracks video-surveyed by remotely operated underwater vehicle in one of the least accessible parts of the Antarctic, we found two- and three-fold increases in the biomass and abundance of glass sponges, respectively, from 2007 to 2011," says Claudio Richter of the Alfred Wegener Institute in Germany. "This is much faster than any of us would have thought possible."