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The first ever treatment for preventing a group of viruses from causing potentially lethal infections has been tested in a phase I clinical trial, and was found to be safe and able to neutralise the viruses, according to results from 40 patients published in The Lancet Infectious Diseases journal. The trial was conducted in healthy participants and further trials will be needed to demonstrate its efficacy in infected patients.
Army scientists working with partners from industry and academia have developed an experimental treatment that protects animals from Sudan virus, which is closely related to Ebola. Their work is published online today in the journal Proceedings of the National Academy of Sciences.
Shift in treatment modalities associated with improved outcomes in uveal melanoma patients with live
PHILADELPHIA - Uveal melanoma - a cancer found in the eye - is rare, comprising less than 5% of all melanomas. Despite successful treatment of the primary tumor in the eye, up to 50% of patients will develop systemic spread (metastasis), most commonly in the liver. A recent study from Massachusetts Eye and Ear Infirmary reported that prognosis of uveal melanoma patients with metastasis is very poor with a median survival of 3.9 months after diagnosis.
BIRMINGHAM, Ala. - People with chronic kidney disease have a higher risk for heart disease and heart-disease death. Now, for the first time in humans, research led by Navkaranbir Bajaj, M.D., of the University of Alabama at Birmingham, has identified a pathological change that appears to link kidney disease to progressive heart disease.
New Rochelle, NY, February 3, 2020--A new study shows that women have many medical questions about the use of cannabis both before and during pregnancy, and during the postpartum period while breastfeeding. While more than half of licensed U.S. healthcare providers responded by saying that perinatal cannabis use was harmful, and nearly half discouraged perinatal cannabis use, many providers missed the opportunity to educate on safety or discourage cannabis use during pregnancy and breastfeeding.
A review of recent clinical trials paints a sobering picture of the usefulness of first-line psychotherapies in treating active duty military personnel and veterans with Post-Traumatic Stress Disorder (PTSD).
Homicide is a leading cause of death among pregnant and postpartum women in Louisiana, according to an analysis of birth and death records from 2016 and 2017. The study, appearing as a research letter in JAMA Pediatrics, was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health. The research team was led by Maeve E. Wallace, Ph.D., of Tulane University School of Public Health and Tropical Medicine in New Orleans.
Pregnant women diagnosed with diabetes who have elevated fasting (pre-meal) blood sugar levels are more likely to face complications than those who have only elevated post-meal glucose levels, according to a new study by a University of Alberta research team.
SPOKANE, Wash. -- English proficiency shouldn't be a barrier to health care. That's why the federal government requires hospitals to make translated documents and interpreters available to patients.
Following a dietary weight loss program can be difficult. Many factors trigger diet lapses, which can lead to weight loss failure. Experts disagree on whether physical activity increases risk or protects against diet lapses. While some studies show exercise leads to overeating by increasing appetite and/or a person’s justification for eating, other studies show exercise regulates hunger and may help reduce overeating.
What The Study Did: Researchers examined how often homicide was the cause of death among women in Louisiana who were pregnant or up to one year postpartum compared with other causes.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Authors: Maeve E. Wallace, Ph.D., of the Tulane University School of Public Health and Tropical Medicine in New Orleans, is the corresponding author.
(doi:10.1001/jamapediatrics.2019.5853)
What The Study Did: Researchers calculated the average cost of recommended initial HIV antiretroviral therapy (ART) regimens in the U.S. from 2012 to 2018 and analyzed how this cost has changed over the years. High ART costs are one of the factors that can lead to poor HIV treatment and outcomes in the U.S.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Montreal, February 3, 2020 -- Most people living with HIV control the virus thanks to antiretroviral therapy (ART). Although this medication is highly effective, the presence of latent viral reservoirs in their bodies means they require lifelong therapy. Studies have demonstrated that immunotherapy combining two anti-HIV antibodies can also suppress HIV, similar to ART.
A study at The University of Texas MD Anderson Cancer Center showed that circulating tumor cells (CTCs), a form of liquid biopsy, was independently associated with melanoma relapse, suggesting CTC assessment may be useful in identifying patients at risk for relapse who could benefit from more aggressive therapy following primary treatment.
SILVER SPRING, Md. - A new study led by scientists at the Walter Reed Army Institute of Research has shown for the first time that a single dose of an experimental Zika vaccine in a dengue-experienced individual can boost pre-existing flavivirus immunity and elicit protective cross-neutralizing antibody responses against both Zika and dengue viruses. Findings were published today in Nature Medicine.