Body

University of Kent research has found that moderate intensity exercise such as brisk walking, water aerobics or cycling can have the most benefcial effect on memory performance.

These findings suggest that it is not necessary for people to carry out highly strenuous exercise to achieve observable improvements in long-term memory, as moderate exercise can have a more positive influence.

A new medical approach recommended by University of Cincinnati physician-researchers may reduce organ wait times, save money, boost quality of life and prolong life expectancy for kidney patients.

According to a computer analysis conducted by faculty in the UC College of Medicine, using kidneys from hepatitis C (HCV)-infected donors for transplant in non-HCV-infected dialysis patients and then treating the infection afterward could reduce the average wait for a kidney from four years to 1.56 years. That's a reduction of 61 percent.

WEST LAFAYETTE, Ind. -- Pancreatic cancer has one of the worst survival rates among cancers. Patients can expect as low as a 9% chance to live for at least five years after being diagnosed.

Going back in time to observe how cells with key gene mutations interact and become invasive would help researchers better understand how the cancer starts and identify it sooner.

CORVALLIS, Ore. - A report released earlier this month dives deep into the ongoing inequities surrounding childbirth in the U.S., with Oregon emerging as a leading example of how to do better.

LOS ANGELES (Feb. 17, 2020) -- New research from the Center for Cardiac Arrest Prevention at the Smidt Heart Institute at Cedars-Sinai shows that rates of sudden cardiac arrest are rising following decades of a downward trend. While this disturbing uptick was observed in both sexes, in women the increase was mostly among those whose sudden cardiac arrest was the first manifestation of heart disease. In men, the increase was mostly among those with known heart disease.

The study was published in the Go Red for Women issue of the peer-reviewed journal Circulation.

People in Ontario living with HIV had a 34 per cent higher incidence rate of chronic obstructive pulmonary disease (COPD) and were diagnosed with the disease about 12 years younger than HIV-negative individuals, according to a study led by researchers at St. Michael's Hospital of Unity Health Toronto and ICES.

Researchers analyzed incidences of COPD among adults 35 years and older who were living with and without HIV between 1996 and 2015 in Ontario - where over 40 per cent of Canadians living with HIV reside.

Genetic tests to predict a person's risk of heart disease and heart attack have limited benefit over conventional testing.

This is the finding from scientists at Imperial College London, who devised a highly sophisticated test analysing thousands of so-called genetic variants linked to heart health.

A genetic study has found evidence to suggest that women who take statins in the long term could be less likely to develop ovarian cancer, according to new research funded by Cancer Research UK published today (Tuesday 18 February)*.

The same result was also found in women who carry the BRCA1/2 gene fault. Having the BRCA1/2 fault puts women at a higher risk of ovarian cancer than the general population**.

About 10% of patients who come to complex care hospitals may have low levels of folate and other indicators of malnutrition, investigators say.

To ensure those patients are identified and helped, those who present with gastrointestinal problems, chronic kidney disease or sepsis -- all associated with malnutrition -- need to have their folate levels tested on admission, they report in the journal Laboratory Medicine.

Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.

1. Low-dose methotrexate associated with small increase in some adverse events

Methotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is the most commonly used drug for systemic rheumatic diseases worldwide and is the first drug a physician will prescribe for a patient with rheumatoid arthritis. But despite its use by millions of people, there is not robust data on the rates of the side effects of the drug.

(SAN ANTONIO) - Recognizing and addressing the widespread problem of sleep disorders in military personnel and veterans, the U.S. Departments of Veterans Affairs and Defense (VA/DoD) jointly have issued new guidelines for assessment and treatment of insomnia and obstructive sleep apnea.

Chlorthalidone, the guideline-recommended diuretic for lowering blood pressure, causes more serious side effects than hydrochlorothiazide, a similarly effective diuretic, according to a new study led by researchers at Columbia University Irving Medical Center. The findings, published in JAMA Internal Medicine, contrast with current treatment guidelines recommending chlorthalidone over hydrochlorothiazide.

Increased risk of mortality from any cause is 44% for women who have experienced domestic abuse, according to study jointly led by the Universities of Warwick and Birmingham

Study highlights the increased risk of developing cardiometabolic diseases such as cardiovascular disease (31%) and type 2 diabetes (51%)

More research is required to determine what factors specifically lead to an increase in mortality, some of it may be linked to the increased risk of cardiometabolic disease

DALLAS, Feb. 17, 2020 -- Longer sitting times were associated with higher levels of heart disease risk among overweight and obese post-menopausal women overall, according to new research published today in the Journal of the American Heart Association, the open access journal of the American Heart Association.