Body
FAIRFAX, Va. (June 15, 2020)-- Interventional radiologists participating in a collaborative house call model in rural Indiana helped reduce emergency department use by 77 percent and hospital readmissions by 50 percent for nearly 1,000 elderly homebound patients with chronic illnesses, according to a research abstract presented during a virtual session of the Society of Interventional Radiology's 2020 Annual Scientific Meeting on June 13.
Irvine, CA - June 12, 2020 - A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.
The study, published today in Nature Communications, titled, "Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots," reveals how the genomic instability induced by the protein APOBEC3A offers a previously unknown vulnerability in cancer cells.
A new modeling study evaluating unfolding COVID-19 epidemics among different income countries reports that, in lower income countries, even if risk is reduced because populations are younger, this benefit is largely negated by limited health system capacity and closer inter-generational contact. In these places, efforts to mitigate the virus will need to be maintained or triggered more frequently, say the authors.
Genetics could help diagnose diabetes in Indians, study shows
A new way of using genetics to diagnose diabetes could pave the way for better diagnosis and treatment in Indians, new research has concluded.
During the COVID-19 pandemic, patients with multiple sclerosis (MS) and their clinicians have had questions and concerns about whether immunotherapies for MS could influence risk for infection or lead to an unfavorable outcome.
LA JOLLA, CA--An extraordinary percentage of people infected by the virus behind the ongoing deadly COVID-19 pandemic never show symptoms of the disease, according to the results of a Scripps Research analysis of public datasets on asymptomatic infections.
Researchers at Massachusetts General Hospital (MGH) have identified a key mechanism in X chromosome inactivation, a phenomenon that may hold clues that lead to treatments for certain rare congenital disorders.
Their findings, published in the journal Developmental Cell on June 11, 2020, may also aid in the creation of novel medicines for certain cancers.
A regular dose of aspirin to reduce the risk of inherited bowel cancer lasts at least 10 years after stopping treatment, research has revealed.
The international trial - known as CAPP2 - involved patients with Lynch syndrome from around the world and revealed that two aspirins a day, for an average of two and a half years, reduced the rate of bowel cancer by half.
CHAPEL HILL - June 11, 2020 - As the COVID-19 pandemic continues with many thousands of new infections reported each day, there is a need for widely applicable surveillance testing to gain a better understanding of infection rates, especially the number of infections in people with mild or no symptoms, who can still be carriers.
Having trouble getting around on your own--such as difficulty walking, climbing steps, or being able to get in and out of a chair--can lead to physical disability and losing your independence.
According to research, being physically inactive is the strongest risk factor for disability as we age.
BALTIMORE, MD (June 12, 2020) - A new University of Maryland study found fentanyl tops the list of drugs detected in overdose patients at two Baltimore hospital emergency departments. The finding suggests that hospitals and medical systems throughout the United States consider adding fentanyl, a potent synthetic opioid linked to most fatal overdoses in Maryland, to their routine drug testing panels. That is the conclusion of researchers at the University of Maryland School of Medicine (UMSOM) and the Center for Substance Abuse Research (CESAR) at the University of Maryland, College Park.
Scientists of Far Eastern Federal University (FEFU), together with German and Russian colleagues, have developed a lead compound to fight chemotherapy-resistant prostate cancer. The original design comes out as scientists combine biologically active molecules from the chemically modified pigment of sea urchins with glucose molecules to deliver the active drug substance inward the tumor cells. A related article recently was published in Marine Drugs.
Rush University Medical Center has opened enrollment for a new clinical trial investigating whether the drug hydroxychloroquine is better than a placebo in preventing COVID-19 infection in healthy people working in health care settings. The Healthcare Worker Exposure Response & Outcomes of Hydroxychloroquine (HERO-HCQ) Trial will enroll 15,000 people from the HERO Registry, an online community of thousands of people working in health care, which supports this and future trials.
CHICAGO --- A new review of neurological symptoms of COVID-19 patients in current scientific literature reveals the disease poses a global threat to the entire nervous system, reports a Northwestern Medicine study published this week in Annals of Neurology.
About half of hospitalized patients have neurological manifestations of COVID-19, which include headache, dizziness, decreased alertness, difficulty concentrating, disorders of smell and taste, seizures, strokes, weakness and muscle pain.
A study published in Molecular Psychiatry shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.
Using stem cells from adults with a clinical diagnosis of depression, the University of Illinois at Chicago researchers who conducted the study also found that fish oil, when tested in the model, created an antidepressant response.