Body
Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a mechanism controlling the development of a type of liver cancer. This study, published today in the Proceedings of the National Academy of Sciences (PNAS), partly funded by the Spanish Association Against Cancer, has identified a protein that, when blocked, dramatically reduces the impact and progression of this type of cancer, called cholangiocarcinoma.
Exercise can slow or prevent the development of macular degeneration and may benefit other common causes of vision loss, such as glaucoma and diabetic retinopathy, new research suggests.
The new study from the University of Virginia School of Medicine found that exercise reduced the harmful overgrowth of blood vessels in the eyes of lab mice by up to 45%. This tangle of blood vessels is a key contributor to macular degeneration and several other eye diseases.
Leaving hospital can be a confusing and sometimes risky time for patients who take medication, with an estimated 44% experiencing medicine-related problems once they get home. New research from the University of Bath suggests the most helpful and timely medicine-related support is provided by hospital pharmacists, yet few patients are aware that they can turn to their NHS Trust to allay confusion and stay safe.
Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in poor prognosis of cancer patients. Through mice experiment, the team also found that the combined usage of an inhibitor and anticancer drug makes chemotherapy more effective.
Women who experience high blood pressure during pregnancy are more likely to develop heart disease and heart failure in later life, according to an international team of researchers.
Winter squash is an important crop grown in the Willamette Valley, and the most important processing cultivar, Golden Delicious, has been grown in Oregon since the 1970s. Over the last two decades, however, growers have noticed yield declines throughout the valley. Agriculture specialists have identified an association between yield decline and disease symptoms such as stunting, vascular discoloration, late-season vine collapse, and root and crown rot, all symptoms of soilborne disease.
EL PASO, Texas - Biology students and faculty members from The University of Texas at El Paso have discovered a new target for tuberculosis drug development. Their study recently was published in the Journal of Biological Chemistry, a publication of the American Society of Biochemistry and Molecular Biology (ASBMB).
Jianjun Sun, Ph.D., associate professor in UTEP's Department of Biological Sciences, led the research on Mycobacterium tuberculosis (Mtb), the bacterial pathogen that causes tuberculosis diseases, or TB.
BOSTON - (June 30, 2020) - Researchers from the Joslin Diabetes Center investigated time trends in pregnancy-related outcomes among women with type 1 diabetes between 2004 and 2017, and found that the percentage of mothers with excess weight gain during pregnancy as well as the use of insulin pumps and CGMs increased significantly, while the prevalence of nephropathy fell dramatically to zero. Furthermore, the research highlights a trend toward increased pre-pregnancy obesity in this population, but the percentage of very large babies born remained the same.
CLEVELAND, Ohio (July 1, 2020)--Perimenopause is a time when women become more vulnerable to a number of health problems. A new study based on data from the Canadian Longitudinal Study on Aging identified menopause as a risk factor for the development of metabolic syndrome or some of its components, including hypertension, central obesity, and high blood sugar. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
A quality improvement initiative in the Neonatal Intensive Care Unit (NICU) at Children's National Hospital led to a significant reduction in treatment with intravenous vancomycin, an antibiotic used for resistant gram positive infections, which is often associated with acute kidney injury. The findings, published in the journal Pediatrics, show the initiative reduceed vancomycin use in patients by 66%, and the NICU has sustained the reduction for more than a year.
WASHINGTON, June 30, 2020 -- While the use of face masks in public has been widely recommended by public health officials during the current COVID-19 pandemic, there are relatively few specific guidelines pertaining to mask materials and designs. A study from Florida Atlantic University, in the Physics of Fluids, from AIP Publishing, looks to better understand which types are best for controlling respiratory droplets that could contain viruses.
WASHINGTON, June 30, 2020 -- Spiders -- what are they good for? The answer, it turns out, is more than just insect control.
Spider silk is useful for a variety of biomedical applications. It exhibits mechanical properties superior to synthetic fibers for tissue engineering, and it is not toxic or harmful to living cells.
Cancer cases have been rising over the years and according to the statistics, the number of people living with cancer will continue to increase. Despite decades of research, cancer treatments are still inefficient and have unacceptable side effects that continue to prompt an urgent need for new approaches to prevention and treatment. Uncovering novel mechanisms associated with cancer would fill current knowledge gaps and help meet this need.
Many small regulatory elements, including miRNAs, miRNA binding sites, and cis-acting elements, comprise only 5~24 nucleotides and play important roles in regulating gene expression, transcription and translation, and protein structure, and thus are promising targets for gene function studies and crop improvement.
Analysis of symptom diaries kept by 256 pregnant women shows that is inaccurate to describe nausea and vomiting in pregnancy as 'morning sickness'
Team led by University of Warwick finds that symptoms can occur at any time of the day
Although likelihood of experiencing symptoms is highest in the morning, nausea was still likely to occur later in the day
First time that the symptom patterns of nausea and vomiting in pregnancy have been mapped