Body
Patients with ALS (amyotrophic lateral sclerosis) often suffer from type 2 diabetes. This phenomenon has since long remained mechanistically enigmatic. Now, researchers at Karolinska Institutet in Sweden have identified a molecular mechanism linking these two diseases. The study is published in the scientific journal PNAS.
The researchers found that immunoglobulin G (IgG) antibodies in the blood of ALS patients target the calcium channel in the cell membrane of the insulin-secreting beta cells in the pancreas.
Los Angeles - Cancer immunology drugs, which harness the body's immune system to better attack cancer cells, have significantly changed the face of cancer treatment. People with aggressive cancers are now living longer, healthier lives. Unfortunately, cancer immunology therapy only works in a subset of patients.
(New York, NY - December 9, 2019) - Mount Sinai researchers have designed an innovative experimental therapy that may be able to stop the growth of triple-negative breast cancer, the deadliest type of breast cancer, which has few effective treatment options, according to a study published in Nature Chemical Biology in December.
The therapy is known is MS1943. In a cancer cell line and mouse models, it degraded a protein called EZH2 that drives the growth of triple-negative breast cancer.
A prescription of short-term exercise for patients with advanced prostate cancer could help to reduce the side-effects of hormone therapy, according to new research from the University of East Anglia.
Researchers from the Norfolk and Norwich University Hospital (NNUH) and UEA led a trial which involved patients who were due to start androgen deprivation therapy (ADT).
Fifty patients took part in the research study, with half of the participants taking part in two supervised exercise sessions a week for three months at specialist exercise science facilities at UEA.
Ever since the German midfielder, Christoph Kramer suffered a black-out in the final of the 2014 Football World Cup there has been a growing number of debates around the question of sport-related concussion. The emphasis here is on correct diagnosis. There are plenty of symptoms but these can be ambiguous.
Taking a baby aspirin every day to prevent a heart attack or stroke should no longer be recommended to patients who haven't already experienced one of these events.
That's according to a new study published in Family Practice.
Nearly one-quarter of Americans over the age of 40 have reported taking aspirin daily even if they don't have a history of heart disease or stroke.
That's a problem, says study author University of Georgia researcher Mark Ebell.
A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent study published by a student researcher at the University of Cincinnati.
A new paper in Family Practice, published by Oxford University Press, found that the widespread use of statins and cancer screening technology may have altered the benefits of aspirin use. Researchers concluded that aspirin no longer provides a net benefit as primary prevention for cardiovascular disease and cancer.
Although HIV infection rates are high among the transgender community in Russia, many transgender people know very little about the virus, as well as their own health status. In Russia's first study to examine transgender people as an at-risk social group for HIV transmission, demographers attribute these high infection rates to the community's social stigmatization and isolation, as well as a lack of access to medical services.
About 10-20 % of all known pregnancies unfortunately end in miscarriage or the loss of a fetus. Despite its common occurrence, there is still a lot of stigma surrounding miscarriage and many women find that their emotional and psychological needs are unmet as they go through a devastating grieving process. In 2014, Dr. Jessica Zucker, a clinical psychologist specializing in women's reproductive and maternal mental health, started a campaign on social media using the hashtag #ihadamiscarriage to address this cultural silence.
WINSTON-SALEM, N.C. - Dec. 9, 2019 - Scientists at Wake Forest School of Medicine have identified a dead probiotic that reduces age-related leaky gut in older mice. The study is published in the journal GeroScience.
But what exactly is leaky gut and what does a probiotic - dead or alive - have to do with it?
First-of-its-kind study used machine learning and health data from the entire Danish population to create sex-specific suicide risk profiles, illuminating the complex mix of factors that may predict suicide.
Podcast permanent link: https://soundcloud.com/cmajpodcasts/190747-res
Patients prescribed anticoagulants after a diagnosis of atrial fibrillation in the emergency department are more likely to continue long-term use of medications to treat the condition, according to research published in CMAJ (Canadian Medical Association Journal).
In a study conducted in Japan, even light to moderate alcohol consumption was associated with elevated cancer risks. In the study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the overall cancer risk appeared to be the lowest at zero alcohol consumption.
Judith Tsui, a UW Medicine clinician specializing in addiction treatment, was seeing more and more patients she was treating for opioid-use disorder also using methamphetamines, a powerful, highly addictive stimulant that affects the central nervous system.
She would start the patients on buprenorphine, a medication to treat opioid use disorder, but they would often drop out.