Body
WASHINGTON -- Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy. Conversely, this treatment combination increased breast cancer development in the offspring whose mothers had not been fed a high fat diet during pregnancy.
Children born prematurely, i.e. before week 37, are more likely to be placed outside the home as a supportive child welfare measure than their full-term counterparts, according to a population study conducted by the Finnish Institute for Health and Welfare (THL). The more premature a child is born, the greater the probability that the child will be placed outside the home.
What The Study Did: Researchers looked at whether certain patterns of connectivity between specific regions of the brain in children at age 7 (measured by magnetic resonance imaging) were associated with later development of symptoms related to attention-deficit/hyperactivity disorder and major depressive disorder.
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A pooled analysis of nine prospective studies involving more than 750,000 adults finds that recommended amounts of leisure-time physical activity were linked to a lower risk for seven cancers, with several cancer types having a 'dose/response' relationship. The study was led by investigators at the National Cancer Institute, the American Cancer Society, and the Harvard T.H. Chan School of Public Health and appears in the Journal of Clinical Oncology.
Above average or high BMI - often linked to cancers, diabetes, cardiovascular and other diseases - may in some cases improve the chance of survival among certain cancers, new research from Flinders University indicates.
Focusing on clinical trials of atezolizumab, a common immunotherapy treatment for non-small-cell lung cancer (NSCLC), the Australian cancer researchers found improved responsiveness to the drug in those with a high body mass index (BMI).
PHILADELPHIA - Proton therapy leads to significantly lower risk of side effects severe enough to lead to unplanned hospitalizations for cancer patients when compared with traditional radiation, while cure rates between the two groups are almost identical. The findings come from an expanded analysis of the largest review of its kind, performed by researchers in the Perelman School of Medicine at the University of Pennsylvania, to evaluate whether or not patients undergoing radiation therapy at the same time as chemotherapy experienced serious adverse events within 90 days.
For most patients, ultrasound is a relatively painless procedure. Conventional ultrasound is safe, low-cost, non-ionizing, and one of the most commonly used imaging modalities worldwide. In a typical exam, a clinician presses an ultrasound probe with gel on the skin surface to generate an image at the desired location. The probe emits sound waves into the tissue and various features such as muscle, fat, blood vessels, and bones reflect sound back to the probe, which records the reflected signals and produces an ultrasound image.
Parkinson's disease is a neurodegenerative disorder that manifests through symptoms such as tremor, slow movements, limb rigidity and gait and balance problems. As such, nearly all diagnostic testing revolves around how a patient moves and requires the patient to walk for extensive distances and amounts of time. The discomfort caused to patients by this kind of testing is unacceptable, according to an international team of researchers based in Saudi Arabia and Sweden.
Natalia Khorkina https://www.hse.ru/en/org/persons/65017 and Marina Lopatina, researchers with the HSE University Department of Applied Economics, examined how the level of physical activity among working Russians changed from 2011 to 2017. They analyzed the results of a survey of Russian men ages 25-60 and women ages 25-55 -- who were either employees, self-employed or ran their own businesses -- conducted by the Levada Center at the request of HSE University.
In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs
The tumor suppressor gene p53, also known as the guardian of the genome, plays a critical function in preventing cancer. Because of its powerful role, it is one of the most commonly compromised genes in cancer.
A high fat diet limits the birth and growth of new neurons in adult female, but not male, mice, according to new research published in eNeuro. Further research could inspire metabolism-based preventions and treatments for brain disorders.
Mobile phone apps are increasingly being used to support breastfeeding decisions - sometimes at a cost, a Flinders University study indicates.
The objective approach of most infant feeding (IF) apps gives mothers a perception of greater control, confidence and efficiency at a time of transition and stress in the early stages of parenting an infant, the study found.
Metabolic diseases such as diabetes and obesity are ever more common globally. In addition to genetic disposition, lifestyle contributes strongly to the prevalence of these metabolic diseases. Precise monitoring methods are needed in order to, for example, evaluate how a change in diet or exercise affects disease and its metabolic characteristics.
Hennigsdorf/Berlin, Germany, December 23, 2019 - Diagnostics company SphingoTec GmbH ("sphingotec", Hennigsdorf, Germany) today announced a publication in Critical Care1 with data on 2,000 ICU patients demonstrating that sphingotec's proprietary biomarker bio-ADM® (Bioactive Adrenomedullin) not only identifies high-risk patients for septic shock at admission but also identifies patients in the general ICU patient population who require immediate life-saving therapeutic intervention.
ANN ARBOR--Leftover prescription opioids pose big risks to kids, yet most parents keep their own and their child's unused painkillers even after they're no longer medically necessary for pain.
But a new University of Michigan study suggests that convenient disposal paired with tailored risk education can improve those numbers.