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Offspring of 2 psychiatric patients have increased risk of developing mental disorders

Offspring of two parents with schizophrenia or bipolar disorder appear more likely to develop the same illness or another psychiatric condition than those with only one parent with psychiatric illness, according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Weight-loss diets may reverse atherosclerosis in obese, overweight people

DALLAS, March 1, 2010 — A low-carbohydrate diet, a low-fat diet and the Mediterranean diet were equally effective in helping obese people to reverse carotid atherosclerosis after losing moderate amounts of weight and improving their blood pressure, in a study reported in Circulation: Journal of the American Heart Association.

Program delivers healthy behaviors door-to-door

In underserved areas like North Philadelphia, existing research shows a nearly 10 percent higher smoking rate than in the general population, with a lower quit rate to boot. The consequences of this public health problem are magnified for new mothers that smoke, as they also expose their babies to the ill effects of second-hand smoke.

Stanford scientists first to identify wide variety of genetic splicing in embryonic stem cells

STANFORD, Calif. — Like homing in to an elusive radio frequency in a busy city, human embryonic stem cells must sort through a seemingly endless number of options to settle on the specific genetic message, or station, that instructs them to become more-specialized cells in the body (Easy Listening, maybe, for skin cells, and Techno for neurons?). Now researchers at the Stanford University School of Medicine have shown that this tuning process is accomplished in part by restricting the number of messages, called transcripts, produced from each gene.

Antifreeze proteins can stop ice melt, new study finds

ATHENS, Ohio (March 1, 2010) — The same antifreeze proteins that keep organisms from freezing in cold environments also can prevent ice from melting at warmer temperatures, according to a new Ohio University and Queen's University study published today in the Early Edition of the journal Proceedings of the National Academy of Sciences.

Pesticide atrazine can turn male frogs into females

Atrazine, one of the world's most widely used pesticides, wreaks havoc with the sex lives of adult male frogs, emasculating three-quarters of them and turning one in 10 into females, according to a new study by University of California, Berkeley, biologists.

The 75 percent that are chemically castrated are essentially "dead" because of their inability to reproduce in the wild, reports UC Berkeley's Tyrone B. Hayes, professor of integrative biology.

Protein-bait interactions, display libraries featured in Cold Spring Harbor Protocols

COLD SPRING HARBOR, N.Y. (Mon., Mar. 1, 2010) -- The use of recombinant proteins, antibodies, small molecules, or nucleic acids as affinity reagents is a simple yet powerful strategy to study the protein/bait interactions that drive biological processes. Analysis via mass spectrometry rather than western blotting extends the identification of interactors, often allowing detection of thousands of proteins from complex mixtures. But this increased sensitivity can lead to problems distinguishing specific interactions from background noise.

M. D. Anderson develops tool to measure severity of chronic graft-vs.-host disease symptoms

ORLANDO, FL - Researchers from The University of Texas M. D. Anderson Cancer Center have developed a new assessment tool to measure the severity of symptoms that can complicate stem cell transplantation. The tool assesses symptoms resulting from chronic graft-versus-host disease (cGVHD), and was presented with supporting research at the 2010 Bone and Marrow Transplant Tandem Meeting.

'Biological clock' could be a key to better health, longer life

CORVALLIS, Ore. – If you aren't getting a good, consistent and regular night's sleep, a new study suggests it could reduce your ability to handle oxidative stress, cause impacts to your health, increase motor and neurological deterioration, speed aging and ultimately cut short your life.

That is, if your "biological clock" genes work the same way as those of a fruit fly. And they probably do.

Ancient DNA from rare fossil reveals that polar bears evolved recently and adapted quickly

BUFFALO, N.Y. -- A rare, ancient polar bear fossil discovered in Norway in 2004 is yielding a treasure trove of essential information about the age and evolutionary origins of the species whose future is now seen as synonymous with the devastation wrought by climate change.

Glue, fly, glue

SALT LAKE CITY, March 1, 2010 – Like silkworm moths, butterflies and spiders, caddisfly larvae spin silk, but they do so underwater instead on dry land. Now, University of Utah researchers have discovered why the fly's silk is sticky when wet and how that may make it valuable as an adhesive tape during surgery.

Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu

COLUMBUS, Ohio – If the behavior of the seasonal form of the H1N1 influenza virus is any indication, scientists say that chances are good that most strains of the pandemic H1N1 flu virus will become resistant to Tamiflu, the main drug stockpiled for use against it.

Researchers at Ohio State University have traced the evolutionary history of the seasonal H1N1 influenza virus, which first infected humans during the 1918 pandemic. It is one of three seasonal influenza A viruses that commonly infect humans. The others are H1N2 and H3N2.

If bonobo Kanzi can point as humans do, what other similarities can rearing reveal?

Because Kanzi, Panbanisha and Nyota were raised in a culture where pointing has a purpose – The Trust's hallmark Pan/Homo environment, where infant bonobos are reared with both bonobo (Pan paniscus) and human (Homo sapiens) influences – their pointing is as scientifically meaningful as their understanding of spoken English, Fields said.

New tool to predict early death or hospital readmission

A new tool can help physicians predict the likelihood of death or readmission to hospital for patients within 30 days of discharge from hospital, according to a new study in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj091117.pdf.

A primer on aspirating breast lumps

A patient with a breast lump that has no features suggesting cancer should still be immediately evaluated, according to a primer for physicians in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj090416.pdf.

This article provides an "in office" approach for immediate evaluation of women who present to their family physician with a breast lump.