Body

Genetic cause discovered for rare bleeding disorder

Hamilton, ON (March 4, 2010) — For some Canadians, any cut such as from dental work or surgery can cause days or more of bleeding. Although they are not hemophiliacs, for some an ordinary bruise can balloon into the size of an orange. For others, knees, elbows and ankles are crippled when bleeding seeps into joints. In very serious cases, hundreds of blood transfusions are required for recovery.

Bacterial balance that keeps us healthy

Heidelberg, 4 March 2010 – The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million, microbial genes in our gut outnumber previous estimates for the whole of the human body.

Psychosurgery makes gentle comeback

Psychosurgery is making a comeback. Recently published case series have shown encouraging results of so-called deep brain stimulation (DBS) in treatment-resistant obsessive-compulsive disorder, depressive disorders, and Tourette syndrome. In the current issue of Deutsches Ärzteblatt International, authors Jens Kuhn (University of Cologne) and Theo P J Gründer (Max Planck Institute, Cologne) and their co-authors provide an introduction to the method (Dtsch Arztebl Int 2010; 107(7)105-13).

Assessing antibiotic breakdown in manure

Agricultural Research Service (ARS) scientist Scott Yates is studying how oxytetracycline (OTC), an antibiotic that is administered to animals, breaks down in cattle manure.

Livestock producers in the United States often use antibiotics to control disease in their animals, and confined U.S. livestock and poultry generate about 63.8 million tons of manure every year. The drugs are often only partially absorbed by the digestive tract, and the rest are excreted with their pharmaceutical activity intact.

American pika are thriving in the Sierra Nevada and southwestern Great Basin

ALBANY, Calif., March 1, 2010—New research addressing climate change questions, a priority focus of the USDA Forest Service Pacific Southwest Research Station, documents that American pika in the Sierra Nevada and southwestern Great Basin are thriving and persist in a wider range of temperatures than previously discovered.

Beta blocker therapy underused in heart failure patients

ST. LOUIS – New Saint Louis University research has found that beta blockers, a class of drugs used to prevent the progression of heart failure and manage arrhythmias (irregular heart beat) and hypertension (high blood pressure), are underused in heart failure patients who receive implantable cardiac devices.

CT scan is cost-effective in screening for LAM among women with collapsed lung

CINCINNATI—Researchers at the University of Cincinnati (UC) have found that it is cost-effective to do CT scan screening of non-smoking women, ages 25-54, who come to the emergency room for the first time with a collapsed lung in order to diagnose and treat those with lymphangioleiomyomatosis, or LAM.

This data is being featured in the online edition of the American Journal of Respiratory and Critical Care Medicine.

CT-scan screening for LAM in women with collapsed lung is cost-effective

Researchers at the University of Cincinnati have found that using high-resolution CT-scans to screen for lymphangioleiomyomatosis, or LAM, is cost-effective in non-smoking women between 25 and 54 who come to the emergency room for the first time with a collapsed lung.

The findings have been published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

Possible vaccine for mesothelioma proven safe

Researchers have demonstrated the safety of a potential vaccine against mesothelioma, a rare cancer associated primarily with asbestos exposure. The vaccine, which infuses uses a patient's own dendritic cells (DC) with antigen from the patient's tumor, was able to induce a T-cell response against mesothelioma tumors.

"[This] is the first human study on DC-based immunotherapy in patients with mesothelioma," wrote Joachim G Aerts M.D., Ph.D., a pulmonary physician at Erasmus Medical Center in the Netherlands.

A novel in vitro model for light-induced wound healing

Washington, DC, USA – Today, during the 39th Annual Meeting of the American Association for Dental Research, convening at the Walter E. Washington Convention Center in Washington, DC, lead researcher C. Millan (U.S.

IU study finds no consensus in definitions of 'had sex'

BLOOMINGTON, Ind. -- When people say they "had sex," what transpired is anyone's guess. A new study from the Kinsey Institute at Indiana University found that no uniform consensus existed when a representative sample of 18- to 96-year-olds was asked what the term meant to them.

'Match' Madness: Picking upsets a losing strategy

BLOOMINGTON, Ind. -- Soon Americans nationwide will begin poring over NCAA men's basketball tournament brackets in their annual attempt at glory -- and maybe even a little cash -- in winning the ubiquitous, albeit illegal, office pool.

Some will go by the numbers, picking the team in each matchup with the best ranking or seed. Others use intuition, sports knowledge, favorite colors, mascot preferences -- it's not called March Madness for nothing -- or other somewhat unscientific methods for picking winners and more importantly, picking the upsets.

A convincing mimic: Scientists report octopus imitating flounder in the Atlantic

MBL, WOODS HOLE, MA—On the open sand plains of the Caribbean seafloor, where soft-bodied animals are routinely exposed to predators, camouflage can be key to survival. Perhaps no group of animals is quite as adept at blending in with its surroundings as cephalopods, who along with relatives the cuttlefish and squid, have evolved a unique skin system that can instantaneously change their appearance.

Hemoglobin A1c outperforms fasting glucose for risk prediction

Measurements of hemoglobin A1c (HbA1c) more accurately identify persons at risk for clinical outcomes than the commonly used measurement of fasting glucose, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.HbA1c levels accurately predict future diabetes, and they better predict stroke, heart disease and all-cause mortality as well. The study appeared in the March 4, 2010, issue of New England Journal of Medicine.

Create new federal center to spur Medicare and Medicaid innovation

Waltham, MA—Despite the loss of the Democrats' supermajority necessary to pass comprehensive national healthcare reform, new federal legislation is needed to promote greater efficiency in the medical delivery system.