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Study looks at gorillas, elephants and logging in Congo

NEW YORK (May 6, 2010) – The Wildlife Conservation Society announced the results of the first-ever evaluation of a large, "landscape-wide" conservation approach to protect globally important populations of elephants and great apes.

Same disease, different stem cell models

In the last three years, a new technique for reprogramming adult cells has given scientists an easier and less controversial way to harness the power of embryonic-like stem cells to study human disease from its earliest beginnings in hopes of gleaning new insights into the root causes of disease and developing new therapies.

But the reprogrammed cells, known as induced pluripotent stem (iPS) cells, are different from embryonic stem cells in their ability to model a human genetic disease, a new cell-to-cell comparison shows.

Biologists discover an extra layer of protection for bacterial spores

Bacterial spores, the most resistant organisms on earth, carry an extra coating of protection previously undetected, a team of microbiologists reports in the latest issue of the journal Current Biology. Their findings offer additional insight into why spores of the bacteria that cause botulism, tetanus, and anthrax survive methods to eradicate them.

The study was conducted by researchers at New York University's Center for Genomics and Systems Biology, Loyola (Ill.) University's Medical Center, and Princeton University's Department of Molecular Biology.

Pluripotent and differentiated human cells reside in decidedly different epigenomic landscapes

Human embryonic stem cells (hESCs) possess remarkable properties of self-renewal and pluripotency, the ability to become almost any kind of cell within the body. And yet they share the same genome or set of genes with lineage-committed cells, cells fated to be or do one thing.

Chromosome 'glue' surprises scientists

Baltimore, MD— Proteins called cohesins ensure that newly copied chromosomes bind together, separate correctly during cell division, and are repaired efficiently after DNA damage. Scientists at the Carnegie Institution have found for the first time that cohesins are needed in different concentrations for their different functions. This discovery helps to explain how certain developmental disorders, such as Cornelia de Lange and Roberts Syndrome arise without affecting cell division essential to development.

Breast cancer metastasis increases after estrogen and progestin hormone therapies, MU study finds

COLUMBIA, Mo. – After menopause, 6 to 10 million women take hormone therapies, which are often a combination of estrogen and progestin, to replace hormones lost from inactive ovaries. Progestin is a hormone that is used to counteract the potentially negative effects of estrogen therapy on the uterus. In studies sponsored by the National Institutes of Health, evidence has been found that estrogen and progestin in hormone therapies increase the risk of breast cancer in post-menopausal women.

IMPAKT Breast Cancer Conference press program

Press releases (embargo: 6 May, 16:45 CEST)

J. Hicks, USAGenome breakthrough allows scientists to identify and profile tumor cells from very small samplesResearchers have developed a powerful new technique for analyzing the genome of single tumor cells. The breakthrough allows them to study in fine detail the biology of how tumors develop.

Genome breakthrough allows scientists to identify and profile tumor cells from very small samples

Brussels, 6 May 2010 -- Researchers from Cold Spring Harbor Laboratory in the USA have developed a powerful new technique for analyzing the genome of single tumor cells. The breakthrough allows them to study in fine detail the biology of how tumors develop and has the potential to help doctors identify dangerous tumor cells from small samples such as fine-needle biopsies from the prostate or a non-invasive lesion in the breast.

Dr James Hicks from Cold Spring Harbor described the new technique at the IMPAKT Breast Cancer Conference in Brussels, Belgium.

Estrogen receptor status of HER2+ breast cancer correlates with response to anti-HER therapies

Brussels, 6 May 2010 -- An international team of researchers has discovered molecular evidence that may explain why some women with HER2 over-expressing breast cancer do not respond to drugs designed to target this important molecule.

The research, presented at the IMPAKT Breast Cancer Conference in Brussels, Belgium, could have an important impact on future clinical trial design and treatment strategies in HER2 over-expressing breast cancer.

Simple gene test identifies clinically important subtypes of breast cancer

Brussels, 6 May 2010 -- A simple genetic test that uses just three genes is among the most effective means of classifying breast cancer into sub-types, US researchers report at the IMPAKT Breast Cancer Conference in Brussels, Belgium. The findings are a significant step in bringing more personalized treatment into breast cancer.

The study is based on the already well-established fact that breast cancer is not one biologically homogeneous disease, but it is composed of several molecular sub-types each of which is characterized by distinct gene expression profiles.

Potential new drug target to combat Kaposi's sarcoma

Research from the University of Leeds has identified how the virus which causes Kaposi's Sarcoma replicates and spreads – opening a door to a possible new treatment for the disease.

Kaposi's Sarcoma is a cancer caused by a human herpes virus and is widespread in sub-Saharan Africa, where it is the most common cause of cancer amongst those infected with HIV.

Information on development cooperation occupies 3.5 percent of the contents of European newspapers

Contrary to what is widely believed, leading newspapers do regularly publish information on development cooperation, although the space dedicated to these issues is generally small in relation to the total of news published since it only occupies 3.5%. Greater coverage of development cooperation can be seen under the sections of international news, reaching a total of 14.8%.

Age, ethnicity and environment impact on risk of falls in elderly men

Falls and fall prevention are a major concern for the elderly and people with osteoporosis, a common chronic disease which causes weak and fragile bones. People with osteoporosis are at increased risk of fracture, even after a minor fall from standing height. A study presented today at the World Congress on Osteoporosis 2010 (IOF WCO-ECCEO10) shows that among elderly men the risk of falling, and thereby breaking a bone, is influenced by age. Most significantly, it also suggests that ethnicity and environment play a role in the risk of falling.

Long-term use of certain contraception injections associated with increased fracture risk

A new study presented today at the World Congress on Osteoporosis (IOF WCO-ECCEO10) in Florence, Italy shows that DMPA, a commonly used injectible contraceptive, is associated with higher risk of bone fracture when used alone, and not in combination with estrogens.

Banks and intelligence services are recommended to communicate to detect Al Qaeda's financing

The exchange of information between authorities and banks is essential to detect Al Qaeda's financing operations. Financial data themselves may not give any hint on how this terrorist group and its related groups get funds. However, when these data are combined with other information held by the intelligence services, it can help banks see an indicator of potentially suspicious activities.