Body

Reshaping the gut microbiome could herald new treatments for bowel diseases

August 24, 2010 – Home to a diverse range of microorganisms, a healthy human body contains at least tenfold more bacteria cells than human cells. The most abundant and diverse microbial community resides in the intestine, and changes to the gut microbiota are linked with diseases such as ulcerative colitis and Crohn's disease.

Health diagnosis made simpler

TEMPE, Ariz. – Arizona State University researchers have demonstrated a way to dramatically simplify testing patients for infectious diseases and unhealthy protein levels.

New testing instrumentation developed by Antonia Garcia and John Schneider promises to make the procedure less costly and produce results in less time.

More research needed on cardiovascular disease in Asian-Americans

There are marked differences in heart disease risk and occurrence among Asian-American subgroups, but data on these subgroups is limited, prompting the American Heart Association to call for more research on this fastest-growing racial/ethnic group in the U.S., according to a scientific statement published in Circulation: Journal of the American Heart Association.

Alcohol intake increases certain types of breast cancer

Alcohol increases the risk of lobular and hormone receptor-positive breast cancer, but not necessarily invasive ductal carcinomas, according to a study published August 23 online in The Journal of the National Cancer Institute.

Nicotine binding to receptor linked to breast cancer cell growth

When nicotine binds to the nicotinic acetylcholine receptor (nAchR), it is known to promote smoking addiction and may also directly promote the development of breast cancer, according to a study published online August 23 in The Journal of the National Cancer Institute.

Sensor important to understanding root, seedling development

Sensor important to understanding root, seedling development

WEST LAFAYETTE, Ind. - A biosensor utilizing black platinum and carbon nanotubes developed at Purdue University will help give scientists a better understanding of how the plant hormone auxin regulates root growth and seedling establishment.

Regulation of cell proliferation is dependent on nucleocytoplasmic trafficking

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the Opioid Growth Factor (OGF, [Met5]-enkephalin) and its receptor, OGFr, a clinically important system with potent antitumor properties, has controlled entry from the cytoplasm to the nucleus. The nucleocytoplasmic passage of OGF-OGFr is critical to cell proliferation and suggests that there are hierarchical levels of nuclear import.

Drugging the undruggable: Advances toward next generation of disease fighters

BOSTON, Aug. 23, 2010 — After decades of dreaming the drug developer's impossible dream, scientists finally are reporting progress in making drugs that target the "untouchables" among the body's key players in health and disease. They are the hundreds of thousands of proteins that many scientists considered to be "undruggable," meaning that previous efforts to develop a drug against them had failed.

UCLA study identifies genetic variation linked to lupus in Asian men

Genes reside along long chains of DNA called chromosomes. UCLA researchers have found that a variation in a gene on the sex chromosome X may enhance an immune response that leads to lupus in men.

Plants give up some deep secrets of drought resistance

MADISON — In a study that promises to fill in the fine details of the plant world's blueprint for surviving drought, a team of Wisconsin researchers has identified in living plants the set of proteins that help them withstand water stress.

The new study, published today (Aug. 23) in the Proceedings of the National Academy of Sciences, identifies the protein targets in cells of a key hormone that controls how plants respond to environmental stresses such as drought, excessive radiation and cold.

Munich researchers demonstrate rocking movement in the anti-stress protein Hsp90

The protein Hsp90 plays a significant role in the survival of cells that are exposed to stress. Researchers at the Technische Universitaet Muenchen (TUM) uncovered this protein's mode of operation some time ago – but now Hsp90 has surprised even the experts with an unexpected pattern of motion. The results are published in the current online issue of the renowned science journal PNAS and may help researchers discover specific cancer medication.

Polyphenol antioxidants inhibit iron absorption

University Park, Pa. — Health benefits from polyphenol antioxidants — substances found in many fruits and vegetables — may come at a cost to some people. Penn State nutritional scientists found that eating certain polyphenols decreased the amount of iron the body absorbs, which can increase the risk of developing an iron deficiency.

Number of uninsured in California counties grew during recession

A new fact sheet from the UCLA Center for Health Policy Research provides detailed county-by-county estimates of the number of California residents who have lost health insurance during the economic downturn.

Following on a statewide estimate published earlier this year, the new analysis finds that the number of Californians without health insurance grew in all counties and that 37 counties — from Imperial to Kern to Shasta — saw uninsured rates increase to nearly one-third of their total non-elderly population (ages 0-64) for all or part of 2009.

Canada needs health-care leadership at federal level

Canada needs a new vision for health at the federal level, writes Dr. Paul Hebert, Editor-in-Chief, CMAJ (Canadian Medical Association Journal) and Matthew Stanbrook, Deputy Editor, in an editorial http://www.cmaj.ca/cgi/doi/10.1503/cmaj.101207 published today.

What the locals ate 10,000 years ago

What the locals ate 10,000 years ago

If you had a dinner invitation in Utah's Escalante Valley almost 10,000 years ago, you would have come just in time to try a new menu item: mush cooked from the flour of milled sage brush seeds.