Body

Scientists are keeping their eye on a new discovery published in the November 2011 print issue of the FASEB Journal (http://www.fasebj.org) that explains what causes some genes to go out of control. Scientists have identified a "cellular switch," called eye transformer, that controls the flow of information from chemical signals outside of the cell to genes in the cell nucleus. This study demonstrates that when eye transformer is turned off, the information pathway it controls (the "JAK/STAT pathway") hyper-activates.

While wind energy has shown strong potential as a large-scale, emission-free energy source, bat and bird collisions at wind turbines result in thousands of fatalities annually. Migratory bats, such as the hoary bat, are especially at risk for collision with wind turbines as they fly their routes in the forested ridges of the eastern U.S. This loss not only impacts the immediate area, but is also detrimental to ecosystem health nationwide—that is, bats help with pest management, pollination and the dispersal of numerous plant seeds.

Everybody knows that if you're physically fit, you're less likely to get a wide range of diseases. What most people don't know is that some people are "naturally" in better shape than others, and this variation in conditioning makes it difficult to test for disease risk and drug effectiveness in animal models.

DETROIT – African Americans are more likely to have a recurrence of uterine cancer despite undergoing a total hysterectomy or a hysterectomy followed by radiation therapy, according to researchers at Henry Ford Hospital in Detroit.

Short courses of antibiotics can leave normal gut bacteria harbouring antibiotic resistance genes for up to two years after treatment, say scientists writing in the latest issue of Microbiology, published on 3 November.

The researchers believe that this reservoir increases the chances of resistance genes being surrendered to pathogenic bacteria, aiding their survival and suggesting that the long-term effects of antibiotic therapy are more significant than previously thought.

Boulder, CO, USA - It's not hard to argue in favor of alternatives to fossil fuels these days, but one popular argument – domestic energy security – may be standing on very shaky legs. A lot of rare metals are needed to make photovoltaic panels, rare earth magnets for wind generators, fuel cells and high-capacity batteries for hybrid and electric vehicles. But most industrialized nations, including the United States, are almost entirely dependent on foreign sources for those metals. The only way this is going to change is if there is more domestic exploration and mining.

The November 2010 issue of "Environmental Pollution" details successful experiments at the University of Cincinnati wherein rabbit's food resulted in the abiotic (non-biological) transformation and absorption of four different types of estrogen, reducing the levels of these estrogen hormones by more than 80 percent in wastewater.

Protected areas are generally seen as a triumph for the preservation of nature, yet the reality on the ground is more complex.

Scientists at Johns Hopkins have taken a less-is-more approach to designing effective drug treatments that are precisely tailored to disease-causing pathogens, such as viruses and bacteria, and cancer cells, any of which can trigger the body's immune system defenses.

DURHAM, N.C. – Chandra Tucker shines a blue light on yeast and mammalian cells in her Duke University lab and the edges of them start to glow. The effect is the result of a light-activated switch from a plant that has been inserted into the cell.

Researchers could use this novel "on-off switch" to control cell growth or death, grow new tissue or deliver doses of medication directly to diseased cells, said Tucker, an assistant research professor in the biology department at Duke.

MADISON -- They are the portals to the cell, gateways through which critical signals and chemicals are exchanged between living cells and their environments.

A team of Melbourne and London researchers have shown how a protein called perforin punches holes in, and kills, rogue cells in our bodies. Their discovery of the mechanism of this assassin is published today in the science journal Nature.

"Perforin is our body's weapon of cleansing and death," says project leader Prof James Whisstock from Monash University.

WINSTON-SALEM, N.C. – Saturday, Oct. 30, 2010 – Researchers at the Institute for Regenerative Medicine at Wake Forest University Baptist Medical Center have reached an early, but important, milestone in the quest to grow replacement livers in the lab. They are the first to use human liver cells to successfully engineer miniature livers that function – at least in a laboratory setting – like human livers. The next step is to see if the livers will continue to function after transplantation in an animal model.

Women with dense breasts and no lobular involution were at a higher risk for developing breast cancer than those with non-dense breasts and complete involution, according to a study published online in The Journal of the National Cancer Institute.

Apart from age, family history, and age at menarche, two additional factors associated with breast cancer risk include mammographic breast density and extent of lobular involution. Lobular involution is the physiological atrophy of the breast epithelium and is known to increase with increasing age.