Body

(Cincinnati, OH) – A groundbreaking study published Friday in the leading scientific journal, Cell, revealed that a team of investigators had successfully generated nerve cells using skin cells from four individuals with Rett syndrome. The study, funded in part by IRSF, was led by Dr. Alysson Muotri at the University of California, San Diego--a leading researcher in the stem cell field.

Irvine, Calif., Nov. 15, 2010 — UC Irvine researchers have discovered that circadian rhythms – the internal body clock – regulate fat metabolism. This helps explain why people burn fat more efficiently at certain times of day and could lead to new pharmaceuticals for obesity, diabetes and energy-related illnesses.

HOUSTON - Red-blood-cell-boosting drugs used to treat anemia may undermine breast cancer treatment with Herceptin, a targeted therapy that blocks the cancer-promoting HER2 protein, researchers from The University of Texas MD Anderson Cancer Center report in the Nov. 16 edition of Cancer Cell.

Cambridge, MA, November 15, 2010 - Epizyme, Inc., a company leading the discovery and development of first-in-class, targeted cancer therapeutics against epigenetic targets, today announced the publication of breakthrough new research in the Proceedings of the National Academy of Sciences (USA). The discovery, centered on the epigenetic enzyme EZH2, illuminates a clear path for the translation of basic science into targeted therapies for the safe and effective treatment of specific forms of human lymphomas.

CAMBRIDGE, Mass. -- A sophisticated new examination of teeth from 11 Neanderthal and early human fossils shows that modern humans are slower than our ancestors to reach full maturity. The finding suggests that our characteristically slow development and long childhood are recent and unique to our own species, and may have given early humans an evolutionary advantage over Neanderthals.

HOUSTON -- (Nov.15, 2010) – In 2009, a Collins County, Texas, jury sentenced Philippe Padieu to 45 years in prison for aggravated assault with a deadly weapon – having sex with a series of women and not telling them he had HIV. An important part of the evidence that identified him as the source of the women's infection came from experts at Baylor College of Medicine (www.bcm.edu) and The University of Texas at Austin (www.utexas.edu/).

AUSTIN, Texas—The source of HIV infection in two separate criminal cases in which men were convicted of intentionally infecting their female sexual partners was confirmed by scientists from The University of Texas at Austin and Baylor College of Medicine using evolutionary forensics.

The research shows it's possible to identify the source of a cluster of diseases by analyzing the evolution of a virus within its host and between individuals. This type of research is known broadly as phylogenetic analysis.

Pinpointing the exact genetic cause of inherited deafness has always involved sequencing one gene at a time, a process that can take up to a year and cost roughly $1,000 per gene. It would cost around $75,000 to test all known deafness causing genes using this approach.

Human childhood is considerably longer than chimpanzees, our closest-living ape relatives. A multinational team of specialists, led by researchers from Harvard University, Max-Planck Institute for Evolutionary Anthropology (MPI-EVA) and the ESRF, applied cutting-edge synchrotron X-ray imaging to resolve microscopic growth in 10 young Neanderthal and Homo sapiens fossils. They found that despite some overlap, which is common in closely-related species, significant developmental differences exist.

Many plants, including crops, release volatiles in response to insect attack. The chemical compounds can be a defense or can be an aromatic call for help to attract enemies of the attacking insect. Researchers from Virginia Tech, Michigan State University, and Georg-August-University Göttingen have discovered how plants produce the defensive compounds.

DALLAS – Nov. 15, 2010 – Tiny molecules called microRNAs act together with hormones to control the onset of labor, raising the prospect that RNA-based drugs might be able to prevent premature labor, researchers at UT Southwestern Medical Center have discovered in a preclinical study.

Marketers hope to connect between the consumer and the products they represent by creating a strong brand identity. Now a Tel Aviv University researcher is giving marketers a heavenly new angle to consider ― religious faith ― on which to build their advertising strategies.

It's just like a bad breakup: People get emotional when they end a relationship with a brand. A new study in the Journal of Consumer Research examines what happens when people turn their backs on the brands they once loved.

You aced that test; now it's time for a treat.

Sometimes pride in an achievement can lead people to indulge in unhealthy choices, according to a new study in the Journal of Consumer Research.