Body

Heart disease, stroke deaths continue to fall but costs remain high

America is winning a battle against heart disease and stroke mortality, but is still losing the war, according to the American Heart Association.

In Heart Disease and Stroke Statistics – 2011, published online in Circulation: Journal of the American Heart Association, the association reports that the death rate from heart diseases declined 27.8 percent from 1997 to 2007 (the most recent final data available), and the stroke death rate fell 44.8 percent.

Body fat distribution associated with a higher risk of ER-negative breast cancer

Body fat distribution does not play an important role in the incidence of every subtype of premenopausal breast cancer, but is associated with an increased risk for estrogen receptor (ER)–negative breast cancer, according to a study published December 15 in The Journal of the National Cancer Institute.

Link between cholesterol compound and multiple sclerosis unlikely, researchers say

New research findings appearing in the January Journal of Lipid Research indicate that compounds called oxysterols are not present in any significant amount in multiple sclerosis patients, contradicting a previous study that suggested that some of these cholesterol metabolites were associated with MS and could be used as diagnostic tools in the clinic.

Vitamin D and parathyroid hormone levels may not affect cardiovascular mortality

New York, NY, December 15, 2010 – There is burgeoning public interest in possible wide-ranging health benefits from vitamin D, including cardiovascular health. In a study published in the December 2010 issue of The American Journal of Medicine, investigators found that there was no independent association between serum levels of vitamin D or parathyroid hormone and cardiovascular mortality in this prospective study, the first in a population of older community-dwelling adults with a low prevalence of vitamin D deficiency and a broad range of kidney function.

Polar bears: On thin ice? Extinction can be averted, scientists say

Polar bears were added to the threatened species list nearly three years ago when their icy habitat showed steady, precipitous decline because of a warming climate.

But it appears the Arctic icons aren't necessarily doomed after all, according to results of a study published in this week's issue of the journal Nature.

The findings indicate that there is no "tipping point" that would result in unstoppable loss of summer sea ice when greenhouse gas-driven warming rises above a certain threshold.

deCODE discovers genetic markers that improve the power of PSA testing for detecting prostate cancer

Reykjavik, ICELAND, 15 December 2010 – Scientists from deCODE genetics and academic colleagues from Iceland, the UK, US, Netherlands, Spain and Romania today report the discovery of a set of single-letter variations in the sequence of the human genome (SNPs) that impact individual baseline levels of prostate specific antigen, or PSA. Testing for PSA levels is the most commonly used screening tool for the detection of prostate cancer. A prostate biopsy is routinely recommended for men with PSA above a certain threshold.

New study about Arctic sea-ice, greenhouse gases and polar bear habitat

ANCHORAGE, Alaska – Sea-ice habitats essential to polar bears would likely respond positively should more curbs be placed on global greenhouse gas emissions, according to a new modeling study published today in the journal, Nature.

The study, led by the U.S. Geological Survey, included university and other federal agency scientists. The research broke new ground in the "tipping point" debate in the scientific community by providing evidence that during this century there does not seem to be a tipping point at which sea-ice loss would become irreversible.

Put on the brakes after foot or ankle surgery

Patients recovering from a right foot injury or surgery should think twice about how soon they want to begin driving again. According to a new study from the Journal of Bone and Joint Surgery (JBJS), it takes much longer to brake when the driver is wearing an immobilization device - like a splint or brace, than it does when wearing normal footwear.

Polar bears still on thin ice, but cutting greenhouse gases now can avert extinction

Polar bears still on thin ice, but cutting greenhouse gases now can avert extinction

Polar bears were added to the threatened species list nearly three years ago as their icy habitat showed steady, precipitous decline because of a warming climate. But it appears the Arctic icons aren't necessarily doomed after all.

Stanford study identifies multitude of genetic regions key to embryonic stem cell development

STANFORD, Calif. — More than 2,000 genetic regions involved in early human development have been identified by researchers at the Stanford University School of Medicine. The regions, called enhancers, are responsible for triggering the expression of distant genes when embryonic stem cells begin to divide to form the many tissues of a growing embryo.

Protein disables p53, drives breast cells toward cancer transition

Protein disables p53, drives breast cells toward cancer transition

HOUSTON - The recently identified TRIM24 protein plays an active role in pushing normal breast cells into rapid cell proliferation and, potentially, into breast cancer.

Warning lights mark shellfish that aren't safe to eat

Red tides and similar blooms can render some seafood unsafe to eat, though it can be difficult to tell whether a particular batch harbors toxins that cause food poisoning.

A new kind of marker developed by chemists at the University of California, San Diego, and reported in the journal ChemComm makes it easier to see if shellfish are filled with toxin-producing organisms.

Researchers discover compound with potent effects on biological clock

Using an automated screening technique developed by pharmaceutical companies to find new drugs, a team of researchers from UC San Diego and three other research institutions has discovered a molecule with the most potent effects ever seen on the biological clock.

Researchers discover compound with potent effects on biological clock

Using an automated screening technique developed by pharmaceutical companies to find new drugs, a team of researchers from UC San Diego and three other research institutions has discovered a molecule with the most potent effects ever seen on the biological clock.

New discoveries make it harder for HIV to hide from drugs

The virus that causes AIDS is chameleon-like in its replication. As HIV copies itself in humans, it constantly mutates into forms that can evade even the best cocktail of current therapies. Understanding exactly how HIV cells change as they reproduce is key to developing better tests and treatments for patients.