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Enhancing nuclear security: Training and international collaboration

While a world free of nuclear weapons remains a goal for governments around the world, nuclear security constitutes a major challenge for the 21st century, as recognised at the 2010 nuclear security summit in Washington. Citizens are generally aware of international efforts to prevent the proliferation of nuclear weapons, but they are often unaware of nuclear security research and the important role science in this field. A new European nuclear security training centre and enhanced international collaboration are good examples.

Plant breeding is being transformed by advances in genomics and computing

The arrival of affordable, high throughput DNA sequencing, coupled with improved bioinformatics and statistical analyses is bringing about major advances in the field of molecular plant breeding. Multidisciplinary breeding programs on the world's major crop plants are able to investigate genome-wide variations in DNA sequences and link them to the inheritance of highly complex traits controlled by many genes, such as hybrid vigor. Furthermore, there has been a step-change in speed and cost-effectiveness.

Misguided public perception on what Tommy John surgery can do apparent in new study

SAN DIEGO, CA – Despite known risks and outcomes of the common elbow procedure known as Tommy John surgery, parents, coaches and players still have incorrect assumptions regarding player performance, say researchers presenting their study at the American Orthopaedic Society for Sports Medicine's Specialty Day in San Diego, CA (February 19th).

Anti-aging hormone Klotho may prevent complications

DALLAS – Feb. 17, 2011 – Low levels of the anti-aging hormone Klotho may serve as an early warning sign of the presence of kidney disease and its deadly cardiovascular complications, according to findings by UT Southwestern Medical Center researchers.

Using mice, investigators found that soft-tissue calcification, a common and serious side effect of chronic kidney disease (CKD), improves when Klotho hormone levels are restored. The study is available online in the Journal of the American Society of Nephrology.

How disordered proteins spread from cell to cell, potentially spreading disease

One bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that's necessary to corrupt other proteins, forming large aggregations linked to several incurable neurodegenerative diseases such as Huntington's, Parkinson's and Alzheimer's.

Stanford biology Professor Ron Kopito has shown that the mutant, misfolded protein responsible for Huntington's disease can move from cell to cell, recruiting normal proteins and forming aggregations in each cell it visits.

Doing good with operations research

For Northwestern University's Karen Smilowitz, the term "industrial engineering" is a bit of a misnomer. It evokes the image of the engineer in a factory with a stopwatch in hand, making sure production is as efficient as possible.

Surely some industrial engineers still do that. But these days, industrial engineering has grown beyond the factory and into the world of business. Others have taken it one step further -- into nonprofits.

Scientists bioengineer a protein to fight leukemia

LOS ANGELES (February 18, 2011) – Scientists at the Children's Center for Cancer and Blood Diseases and The Saban Research Institute of Children's Hospital Los Angeles today announced a breakthrough discovery in understanding how the body fights leukemia. They have identified a protein called CD19-ligand (CD19-L) located on the surface of certain white blood cells that facilitates the recognition and destruction of leukemia cells by the immune system.

1 person of 1,900 met AHA's definition of ideal heart health, says University of Pittsburgh study

PITTSBURGH, Feb. 18 – Only one out of more than 1,900 people evaluated met the American Heart Association (AHA) definition of ideal cardiovascular health, according to a new study led by researchers at the University of Pittsburgh School of Medicine. Their findings were recently published online in Circulation.

'Telecoupling' explains why it's a small (and fast) world, after all

WASHINGTON, D.C. -- Understanding and managing how humans and nature sustainably coexist is now so sweeping and lightning fast that it's spawned a concept to be unveiled at a major scientific conference today.

Meet "telecoupling."

Joining its popular cousins telecommuting and television, telecoupling is the way Jack Liu, director of the Human-Nature Lab/Center for Systems Integration and Sustainability at Michigan State University, is describing how distance is shrinking and connections are strengthening between nature and humans.

Multiple approaches necessary to tackle world's food problems

Researchers need to use all available resources in an integrated approach to put agriculture on a path to solve the world's food problems while reducing pollution, according to a Penn State biologist. Changes in national and international regulations will be necessary to achieve this goal.

Lithium: Fountain of youth from the tap?

(Jena, Germany) Professor Dr. Michael Ristow's team along with Japanese colleagues from universities in Oita and Hiroshima have demonstrated by two independent approaches that even a low concentration of lithium leads to an increased life expectancy in humans as well as in a model organism, the roundworm Caenorhabditis elegans. The research team presents its results in the online edition of the scientific publication European Journal of Nutrition which is now online (see hyperlink below).

Study links hypoxia and inflammation in many diseases

AURORA, Colo. (Feb. 18, 2011) -- When the body is deprived of oxygen during a major surgery, the kidneys, heart muscles or lungs can be injured as a result. The problem is that lack of oxygen can lead to inflammation.

Yet some athletes deliberately train at high altitude, with less oxygen, so they can perform better. Their bodies adapt to the reduced oxygen.

Efficacy of tuberculosis vaccine enhanced

Nele Festjens and Nico Callewaert of VIB and Ghent University have improved the efficacy of the vaccine for tuberculosis. The new vaccine affords - as already proven in mice - better protection against the disease. The development of a new tuberculosis vaccine is a priority in the fight against the disease which claims the lives of 1.7 million people each year. The current vaccine provides only partial protection.

Scheduled deliveries raise risks for mothers, do not benefit newborns

Inducing labor without a medical reason is associated with negative outcomes for the mother, including increased rates of cesarean delivery, greater blood loss and an extended length of stay in the hospital, and does not provide any benefit for the newborn. As the number of scheduled deliveries continues to climb, it is important for physicians and mothers-to-be to understand the risks associated with elective induction.

High-caffeine-consuming boys get greater rush from caffeine than girls

BUFFALO, N.Y. -- Among the many differences between girls and boys, add the effects from caffeine -- physiological, behavioral and subjective -- to the list.

Results of a double-blind, placebo-controlled, dose-response study of the response of youth to caffeine found that, in general, boys get a greater rush and more energy from caffeine than girls.

Boys also reported they felt that caffeine had a positive effect on their athletic performance. Girls didn't report on this issue.