Eurekalert

Hepatocellular carcinoma (HCC), the main form of primary liver cancer, is one of the leading causes of tumor-related death worldwide.

"The growth hormone secretagogue receptor type 1a (GHS-R1a) is the known biological relevant receptor of the endogenous ligand and pleiotropic hormone Ghrelin (acronym growth hormone release inducing), which mediates a broad range of complex biological functions [1], such as regulation of the body weight, body composition and energy expenditure."

The smoke from the extreme forest fires on the US West Coast in September 2020 travelled over many thousands of kilometres to Central Europe, where it continued to affect the atmosphere for days afterwards. A comparison of ground and satellite measurements now shows: The forest fire aerosol disturbed the free troposphere over Leipzig in Germany as never before.

The present Oncotarget work shed light on a brief mechanistic framework of PTs aggressive nature and present potential biomarkers to differentiate overlapping FELs that would be of practical utility in augmenting existing diagnosis and disease management for this rare tumor.

A series of autopsies performed in an infectious disease hospital in the Brazilian Amazon reveals that infections by the Histoplasma fungus are a major cause of death in people with HIV. The study, led by Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation, in collaboration with a team in Manaus, highlights the need of implementing sensitive methods to detect these infections in Histoplasma-endemic regions.

Chronic lymphocytic leukemia (CLL) is characterized by gradual accumulation of neoplastic B cells.

Researchers at DTU Health Tech have developed a new material that can facilitate a near-perfect merger between machines and the human body for diagnostics and treatment.

RUDN mathematician and his colleagues from China, Egypt, Saudi Arabia, United Kingdom, and Qatar have developed an algorithm allowing the distribution of computing tasks between the IoT devices and the cloud in an optimal way. As a result, the power and time costs are reduced by about three times.

Right-wing voices set out powerful but misleading arguments to justify inaction by the Trump administration during the COVID-19 pandemic, according to a new study of the rhetoric used by high-level government officials and influential commentators in the US during the first half of 2020.

University of Calgary study shows BPA exposure below regulatory levels can impact development of the brain's sleep centre, effecting behavior. The researchers found striking changes to the brain region responsible for driving circadian rhythms. The suprachiasmatic nucleus, located in the hypothalamus, failed to develop properly. This change can have implications for sleep, activity levels, and other behaviors. Bisphenol A, also known as BPA is commonly found in plastics, and canned food linings.

Machine learning, when used in climate science builds an actual understanding of the climate system. This means we can trust machine learning and further its applications in climate science, say the authors.

The University of Ottawa's Positive Energy program released new survey results showing that a large segment of the Canadian public does not trust the courts to settle disputes over energy projects or climate policy. The survey was conducted by Positive Energy's official pollster, Nanos Research.

Using a Fitbit and a spy mic, scientists have discovered new insight into the behavior of the elusive Canada lynx. A new study by researchers from McGill University, University of Alberta, and Trent University provides a first look at how miniaturized technology can open the door to remote wildlife monitoring.

The so-called Plexin-A1 gene seems to play a more extensive role in brain development than previously assumed. This is shown by a current study led by the University of Bonn (Germany) with more than 60 international partners. The gene is also interesting for another reason: Its mutations are inherited either dominantly or recessively, depending on which part of the gene is affected. The results of the study are published in the journal "Genetics in Medicine".

The study recently published in Biomedical Optics Express and authored by members of the consortium reports on several study cases and clinical tests conducted to validate the accuracy and high quality of measurements achieved by the LUCA device.

Energy communities will play a key role in building the more decentralized, less carbon intensive, and fairer energy systems of the future. Such communities enable local prosumers (consumers with own generation and storage) to generate, store and trade energy with each other -- using locally owned assets, such as wind turbines, rooftop solar panels and batteries.

Researchers use the abundant chemical element manganese as active material.

YouTube is a treasure trove of virtual reality fails: users tripping, colliding into walls and smacking inanimate and animate objects. By investigating these "VR Fails" on YouTube, researchers at the University of Copenhagen have sought to learn more about when and why things go sideways for users and how to improve VR design and experiences so as to avoid accidents.

Researchers from Trinity College Dublin have developed a novel set of tools for designing vitamin D clinical trials that capture large seasonal and population-wide differences in vitamin D status, typically seen in individuals. Their study provides a framework for clinical trials to establish whether vitamin D supplementation is effective against a given disease.

In many species including humans, the cells responsible for reproduction, the germ cells, are often highly interconnected and share their cytoplasm. In the hermaphrodite nematode Caenorhabditis elegans, up to 500 germ cells are connected to each other in the gonad, the tissue that produces eggs and sperm. These cells are arranged around a central cytoplasmic 'corridor' and exchange cytoplasmic material fostering cell growth, and ultimately produce oocytes ready to be fertilized.