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Toward one drug to treat all coronaviruses
Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever. Now, researchers reporting in ACS' Journal of Proteome Research have analyzed viral proteins across 27 coronavirus species and thousands of samples from COVID-19 patients, identifying highly conserved sequences that could make the best drug targets.
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Thumb-sized device quickly 'sniffs out' bad breath
No one wants bad breath -- not when visiting friends and family, at a job interview, and especially not on a first date. Smelly breath can make things awkward, but it also is a natural warning sign, indicating that serious dental issues are occurring. Now, researchers reporting in ACS Nano have constructed a portable, thumb-sized device that diagnoses bad breath by quickly "sniffing" exhalations for the gas that makes it stinky -- hydrogen sulfide.
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Study innovates in gluten-free formulations, creating more palatable and nutritious bread
Study at the Federal University of São Paulo developed a recipe combining chickpea flour and psyllium, a plant-derived soluble fiber. The product is nourishing and rated highly by consumers in qualitative surveys.
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New scoring system for assessing wound healing
Evaluating the efficacy of novel therapies requires the ability to monitor wound progression accurately and reproducibly over time. Researchers have proposed a new scoring system for wound healing in mice based on parameters in each phase of healing
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Toxicity testing on the placenta and embryo
Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.
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A new model of coral reef health
Scientists have developed a new way to model and map the health of coral reef ecosystems using data collected on the Global Reef Expedition. This innovative method, presented today at the International Coral Reef Symposium (ICRS), can determine which natural and anthropogenic factors are most likely to lead to persistently vibrant coral and fish communities. Their findings can help scientists identify the reefs most likely to survive in a changing world.
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Sandia designs better batteries for grid-scale energy storage
Researchers at Sandia National Laboratories have designed a new class of molten sodium batteries for grid-scale energy storage. The new battery design was shared in a paper published today in the scientific journal Cell Reports Physical Science.
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New in the Hastings Center Report, July-August 2021
New in the Hastings Center Report: Should ethicists be activists? Four calls to action, and more in the July-August 2021 issue.
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Advancing the long-term well-being of people living with HIV
A global multidisciplinary group of HIV experts led by CUNY SPH Senior Scholar Jeffrey Lazarus and including Distinguished Professor Denis Nash and Associate Professor Diana Romero developed a consensus statement identifying the key issues health systems must address in order to move beyond the longtime emphasis on viral suppression to instead deliver integrated, person-centered healthcare for people living with HIV throughout their lives.
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New method predicts COVID-19 severity, could help with hospital triage
During the height of the pandemic, some hospitals were overwhelmed with patients seeking treatment for COVID-19. This situation could happen again during future outbreaks, especially with SARS-CoV-2 variants of concern on the rise. Now, researchers reporting in ACS' Analytical Chemistry have developed a blood test to predict which people infected with COVID-19 are most likely to experience serious symptoms, which could help health care workers prioritize patients for hospitalization and intensive care.
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Wearable brain-machine interface turns intentions into actions
An international team of researchers led by Georgia Tech is combining soft scalp electronics and virtual reality in a brain-interface system, recently published in Advanced Science.
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Toxic facility relocation depends on community pressure
No one wants to live near a toxic plant. Toxic-releasing facilities such as paper, pulp, and other manufacturing plants negatively affect human health, environmental quality, and property values. And communities with lower income and educational attainment are more likely to house such facilities.
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A global comparison of life-cycle GHG emissions from passenger cars
A new study of the life-cycle GHG emissions from passenger cars sharply distinguishes the climate impacts of electric vehicles and combustion vehicles. It finds that only battery electric vehicles and fuel-cell electric vehicles powered by renewable electricity can achieve the kind of reductions in GHG emissions from transportation that comport with Paris Agreement goals. There is no realistic pathway that relies on combustion-engine vehicles, including hybrids of any sort.
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A novel method for the rapid repair of peripheral nerve injuries
One of the main problems preventing optimal regeneration following peripheral nerve injuries is that axons within severed nerves have difficulty regenerating and reaching their target. This may be attributed in part to misguided axons that sprout in multiple directions, decreasing probability to reach their target organs. A new technique, engineered by researchers at Bar-Ilan University in Israel, fills a nerve conduit with gel containing physical and chemical components that promote and align axon regrowth.
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Researchers discover nucleotide sequence responsible for effectively fighting pathologies
Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors). The discovery will help predict errors in microRNA behaviour and create drugs that can detect targets (such as viruses) more effectively. The results of the study have been published in the RNA Biology journal.
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Traditional Japanese food may hold building blocks of COVID-19 treatments
Natto, a fermented soybean dish often served for breakfast in Japan, originated at the turn of the last millennium but may hold an answer to a modern problem: COVID-19, according to a new study based on cell cultures.
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The need for nuance in carbohydrate recommendations
Without a standard definition for carbohydrate quality, some foods that contain carbohydrates are often stigmatized based on isolated and reductionist assessment methods that fail to consider their contributions to nutrient intakes and balanced, healthy diets. In a new perspective piece, published in Advances in Nutrition, authors call for a more holistic approach to carbohydrate guidance to address the complex needs of both people and the planet.
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Researchers develop tool that may help in understanding inaccuracy in eyewitness testimony
Researchers at the University of Toronto have developed an innovative tool to aid in the investigation of how we perceive and remember visual experiences. The new tool, referred to as a "scene wheel," will help researchers study how accurately we construct mental representations of visual experiences for later retrieval -- for example, how well an eyewitness recalls details of a crime or an accident.
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Awareness without a sense of self
In the context of meditation practice, meditators can experience a state of "pure awareness" or "pure consciousness", in which they perceive consciousness itself. This state can be experienced in various ways, but evidently incorporates specific sensations as well as non-specific accompanying perceptions, feelings, and thoughts.
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Patients may face barriers due to race, ethnicity and language at hospital discharge
A survey of 224 recently discharged patients was conducted in five languages just before the COVID-19 pandemic and highlighted challenges, including limited understanding of medications; lack of available professional medical interpreters and translated patient instructions at discharge; and worries about support for at home after hospitalization.
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