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Discerning molecular interactions may be target of precision medicine for severe COVID-19
lncRNAs are potential regulators of anti-viral response during severe SARS-CoV-2 infection. Researchers constructed a gene co-expression network that measures the relationship of gene expression patterns across a group of samples. They identified four differentially expressed lncRNAs strongly correlated to the protein-coding genes in a novel network enriched for different immune-related processes associated with dysregulated cytokine production. The four were identified as "hubs", signifying their association with cytokine over-production due to fierce immune response.
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Exercise reduces risk of airway disease
Exercise appears to reduce the long-term risk of bronchiectasis, a potentially serious disease of the airways, according to a new study.
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Linguists predict unknown words using language comparison
Researchers from SOAS University of London and the Max Planck Institute for the Science of Human History have published a new paper in the renowned international journal for historical linguistics, Diachronica. Their paper describes an experiment that illustrates how the classical method for the reconstruction of unattested languages can also be used to predict hitherto undocumented words in poorly described and endangered languages of India.
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Men's loneliness linked to an increased risk of cancer
A recent study by the University of Eastern Finland shows that loneliness among middle-aged men is associated with an increased risk of cancer.
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Limited value of tree plantations for biodiversity conservation
Tree plantations are supposed to help compensate the loss of pristine forest habitats. However, their contribution to biodiversity conservation is limited: For example, plantations host a significantly lower number of beetle species as well as individuals than old-growth forests. This was found by a global analysis published in Forest Ecology and Management and led by the German Centre for Integrative Biodiversity Research (iDiv), Friedrich Schiller University Jena (FSU) and Martin Luther University Halle-Wittenberg (MLU).
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The first comprehensive single-cell atlas of human teeth
Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approaches.
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Life in a wheatbelt oasis
Western Australia's wheatbelt is a biodiversity desert, but the remaining wildlife - surviving in 'wheatbelt oases' - may offer insights for better conservation everywhere, according to researchers.
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Breakthrough in the understanding of a protein with a key role in several cancers
The neutron reflexometry method has given scientists an atomic-level insight into the behaviour of Bcl-2, a protein that promotes cancerous cell growth. The new study was carried out by Umeå chemists in collaboration with the research facilities ESS and ISIS and is published in Nature Communications Biology.
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The new EU climate target could phase out coal power in Europe as early as 2030
Tightening the EU emissions trading system (EU ETS) in line with the EU Green Deal would dramatically speed up the decarbonization of Europe's power sector - and likely cause a demise of the coal industry.
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Scientists created technology to detect and treat complex arrhythmias
Researchers have developed a breakthrough method for quickly, accurately, and reliably diagnosing cardiac arrhythmias. It coped with the task in 38 cases out of 51. In other words, it is highly effective in almost 75% of cases.
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International research team discovers new two-dimensional material
An international team with researchers from the University of Bayreuth has succeeded for the first time in discovering a previously unknown two-dimensional material by using modern high-pressure technology. The new material, beryllonitrene, consists of regularly arranged nitrogen and beryllium atoms. It has an unusual electronic lattice structure that shows great potential for applications in quantum technology.
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New clues on how networks such as Twitter are organized to respond to viral news
A thesis defended at the UOC analyses the structural patterns of complex systems such as social networks
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Portopulmonary hypertension in patients with chronic liver disease
Portopulmonary hypertension (PoPH) is a form of pulmonary arterial hypertension (PAH). PoPH occurs in approximately 15% of patients with PAH, and is reportedly found in 2-6% of patients with portal hypertension and 1-2% of patients with liver cirrhosis according to studies from Europe and America. However, the real-world data on PoPH in Japan are largely unknown, with many questions on the condition's etiology and prevalence.
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New research on why mutations in a gene leads to mitochondrial disease
Monash University researchers have uncovered for the first time the reason mutations in a particular gene lead to mitochondrial disease.
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The bluest of blue: A new algae-based switch is lighting up biological research!
A group of scientists from the Nagoya Institute of Technology, Japan, have discovered a novel ion channel protein that can be controlled by light, in a species of terrestrial alga. These channels respond to the shorter indigo blue wavelength of light, the first discovery of its kind. Subsequent light-based manipulations of the channel find potential applications in the modulations of specific functions of nerves, muscles, and more, for biological research.
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Loss of fauna in tropical forests impedes achieving Sustainable Development Goals
A new publication from scientists at LUCSUS and Leibniz-IZW explores the links between defaunation of tropical forests and the United Nations Sustainable Development Goals (SDGs). In a paper published in the scientific journal "Ambio" they illustrate how losing an abundant and diverse fauna undermines food security, increases the risk of infectious disease outbreaks, reduces the capacity of carbon storage and thereby weakens fundamental pillars of sustainable global development.
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Future drones likely to resemble 300-million-year-old flying machine
University of South Australia researchers have drawn inspiration from a 300-million-year-old superior flying machine - the dragonfly - to show why future flapping wing drones will probably resemble the insect in shape, wings and gearing.
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Value from sewage? New technology makes pig farming more environmentally friendly
A novel nitrate removal system can clean up the wastewater produced by swine farms in Okinawa, says researchers at the Okinawa Institute of Science and Technology Graduate University. The study was published in Bioresource Technology.
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Cholestenone shows antibiotic properties against H. pylori
Helicobacter pylori, a gram-negative pathogen that has infected half of the world's population is a Group I carcinogen according to the WHO. H. pylori resides in the gastric mucosa causing gastritis, ulcers, gastric cancers and gastric malignant lymphoma. It can be eradicated in most infected people using a combination of three drugs including antibiotics clarithromycin. However drug-resistant H. Pylori is a growing problem and it is expected to develop drugs that exhibit anti-H. pylori activity.
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Plasma acceleration: It's all in the mix
The LUX team at DESY is celebrating not just one but two milestones in the development of innovative plasma accelerators. The scientists from the University of Hamburg and DESY used their accelerator to test a technique that allows the energy distribution of the electron beams produced to be kept particularly narrow. They also used artificial intelligence to allow the accelerator to optimise its own operation. The scientists are reporting their experiments in two papers published shortly after one another in the journal Physical Review Letters.
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