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A new study, published in JCI insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity. The researchers believe that Brd4 could be used as a target for obesity and insulin resistance.

Research finds that a commonly used risk-prediction model for lung cancer does not accurately identify high-risk Black patients who could benefit from early screening.

The Geological Society of America regularly publishes articles online ahead of print. For April, GSA Bulletin topics include multiple articles about the dynamics of China and Tibet; the Bell River hypothesis that proposes that an ancestral, transcontinental river occupied much of northern North America during the Cenozoic Era; new findings in the climatic history during one of Earth's coldest periods: The Late Paleozoic Ice Age; and the age an nature of the Chicxulub impact crater.

You know that raw overwhelm people have been reporting after months of a pandemic, compounded by economic issues and social unrest? Does fatigue and compulsive social media scrolling strike a familiar chord?

A new case report, detailed in Annals of Emergency Medicine, is the first known case of a patient with VITT (vaccine-induced thrombotic thrombocytopenia) treated with a heparin alternative following the Centers for Disease Control and Prevention (CDC) guidance.

In Frontiers in Immunology, pathologists outline how the immunome -- all of the genes collectively expressed by an individual's immune cells -- holds the potential to provide researchers and physicians with unprecedented insight into an individual's health.

For patients with brain metastases, amino acid positron emission tomography (PET) can provide valuable information about the effectiveness of state-of-the-art treatments. When treatment monitoring with contrast-enhanced magnetic resonance imaging (MRI) is unclear, adding 18F-FET PET can help to accurately diagnose recurring brain metastases and reliably assess patient response. This research was published in The Journal of Nuclear Medicine.

Scientists have shed light on why some people who have a stroke do not also have abnormal heart rhythms, even though their hearts contain similar scar tissue.

New research by University of Tennessee, Knoxville, Lecturer of Earth and Planetary Sciences Stephanie Drumheller sheds light on how ancient giant crocodiles changed their diet as they matured.

From the very beginning of the AIDS epidemic in 1981, nurses have been at the forefront of patient care, advocacy, and research. But even in the age of antiretroviral therapy and pre-exposure prophylaxis, many challenges remain in reducing the impact of HIV and AIDS, according to the special May/June issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.

Micropropagation is a technique used for growing large quantities of new plants from fewer "parent" plants, yielding clones with the same, predictable qualities. The cannabis (Cannabis sativa) industry, however, has been largely left out of this beneficial technique, because this species of plant is extremely difficult to micropropagate.

The combination approach uses immune checkpoint inhibitors with ATRA, a safe medication that is widely used to treat leukemia.

Researchers analyzed the effects of wildfires on plant cover and soil quality in the last 40 years. The findings of the study show that the forest is highly vulnerable even in well-conserved areas far from the 'deforestation arc'.

New findings from Ontario have shown that children born in Sarnia have a higher risk of developing asthma compared to neighbouring cities. A research team from Lawson Health Research Institute and Western University, using provincial data from ICES, found that higher air pollution exposure in the first year of life very likely contributed to this higher risk.

Despite increased use of repetitive transcranial magnetic stimulation in psychiatry, the rates at which patients respond to the therapy and experience remission of often-disabling symptoms have been modest at best. Now, a team of University of South Florida psychiatrists and biomedical engineers applied an emerging functional neuroimaging technology, known as diffuse optical tomography (DOT), to better understand how rTMS works so they can begin to improve the brain stimulation procedure's effectiveness in treating depression.

Studying protein changes in the kidneys as we age, as well as the transcription of genes into proteins, helps provide a full picture of the age-related processes that take place in these organs.

Researchers have found that people who live beyond 105 years tend to have a unique genetic background that makes their bodies more efficient at repairing DNA, according to a study published today in eLife.

Over the years, physicians and historians have attributed Shackleton's failing health during his Antarctic expeditions to scurvy or a congenital heart defect. By studying other explorers and learning they had symptoms comparable to those of Shackleton, researchers concluded that beriberi provided a sound scientific and medical explanation for the famed explorer's health struggles.

Giant vortices of floating plastic trash in the world's oceans with sometimes devastating consequences for their inhabitants - the sobering legacy of our modern lifestyle. Weathering and degradation processes produce countless tiny particles that can now be detected in virtually all ecosystems. But how dangerous are the smallest of them, so-called nanoplastics?

Researchers have identified more than 250 "severity associated" proteins in the worst cases of COVID-19. These findings could help researchers identify the mechanisms that cause severe COVID-19.