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Through a unique combination of computer simulations and laboratory experiments, researchers at the Paul Scherrer Institute PSI have discovered new binding sites for active agents - against cancer, for example - on a vital protein of the cell cytoskeleton. Eleven of the sites hadn't been known before. The study is now published in the journal Angewandte Chemie International Edition.

COVID-19 primarily involves the respiratory system, dysfunction in multiple organ systems is common, particularly in the cardiovascular, gastrointestinal, immune, renal, and nervous systems. Patients with transthyretin amyloidosis (ATTR) (a disease caused by an abnormal misfolded protein that causes buildup of amyloid deposits in the heart, peripheral nervous system including the autonomic nervous system, or other organs) represent a population particularly vulnerable to COVID-19 morbidity due to the multisystem nature of ATTR amyloidosis.

Researchers have found an independent association between COVID-19-related income loss and financial strain and depression, according to the latest study from the COVID-19 Resilience Project, run by the Lifespan Brain Institute (LiBI) of Children's Hospital of Philadelphia (CHOP) and Penn Medicine. This association was found in two separate cohorts - one primarily in the United States and one in Israel - and the depressive symptoms worsened over time in participants who were hit financially, above and beyond pandemic-related anxiety.

Researchers have developed an organic-inorganic hybrid crystal which consists of chains in a single direction, yet still forms two-dimensional layers in spite of this. This makes it possible to combine different material components, like pieces in a construction set, to create tailored materials with innovative properties.

A recent study analyses data collect4d at 44 of the darkest places in the world, including the Canary Island Observatories, to develop the first complete reference method to measure the natural brightness of the night sky using low-cost photometers.

Solar-power developers need to explore using lower-quality agricultural land for solar energy, incentivize dual-use (combined agriculture and solar) options, avoid concentrated solar development and engage communities early to achieve New York's green energy goals, according to forthcoming Cornell University research.

Scientists at Tokyo Tech experimentally verify the existence of exotic surface conduction states in topological semimetals (TSMs), materials that lie at the boundary between conductors and insulators, by performing voltage scans of these surface states on a thin film sample of a TSM. The findings can pave the way for future study and exploitation of such conduction states in realizing novel, quantum transport phenomena.

An article published in International Journal of Hyperthermia proposes a more effective protocol for the treatment of cardiac arrhythmias when applying radiofrequency energy at the site of the arrhythmia by catheterization. The research results from the final year project on the bachelor's degree in Biomedical Engineering by Sergi Coderch Navarro, supervised by Ana González Suárez and Oscar Camara, researchers with the PhySense group of the BCN MedTech Research Unit.

Clinical practice guidelines for dealing with the physical and mental health of transgender people highlight the current lack of a solid research base which must be improved, according to a new study published in the journal BMJ Open.

The world's first-ever 'academic paper which is not a paper' is due to be presented by a Lancaster University research team at the premier international conference on human-computer interaction.

Social media has become a platform for new mothers to openly share their experiences of the joys and challenges of parenthood. Researchers at Penn State and Dalhousie University have unraveled the sentiments in nursing mothers' tweets to better understand the factors influencing breastfeeding behaviors. They hope the findings can inform policies and interventions to support and improve resources for nursing mothers, such as breastfeeding support, workplace accommodations and technological aids such as apps.

The New England Journal of Medicine (NEJM) today published findings of the Phase 2b clinical trial conducted in South Africa.NEJM is recognised as the world's leading medical journal.Shabir Madhi, Professor of Vaccinology, co-author of the study, and the Director of the Vaccines & Infectious Diseases Analytics Research Unit (Wits VIDA), led the Novavax Covid-19 vaccine trial in South Africa.

The study published in the Clinical Nutrition journal was carried out on a group of participants aged 65 and above. However, investigators claim the results could be extrapolated to other age groups.

Scientists at the Institute for Basic Science realized the higest laser intensity reached in history. The record-breaking laser intensity over 1023 W/cm2 enables us to explore novel physical phenomena occurring under extreme physical conditions.

Researchers have demonstrated a record-high laser pulse intensity of over 1023 W/cm2 using the petawatt laser at the Center for Relativistic Laser Science (CoReLS), Institute for Basic Science in the Republic of Korea. It took more than a decade to reach this laser intensity, which is ten times that reported by a team at the University of Michigan in 2004. These ultrahigh intensity light pulses will enable exploration of complex interactions between light and matter in ways not possible before.

Scientists proposed a new method to realize photocatalytic conversion of biopolyols to syngas at room temperature with high efficiency.

Research conducted by the University of Birmingham shows in order to have an effective Covid-19 vaccination rollout it has to be widely accepted by the entire population.

A geoscientific research team led by scientists from the University of Cologne has come a decisive step closer to determining the oxygen levels in the early Earth's history by analysing the composition of tungsten isotopes / publication in PNAS

Almost one in six people worldwide live with obesity, which may have serious health consequences. In the world's most recognized medical journal, Danish researchers now document how to effectively achieve and maintain a healthy weight loss.

Research led by the University of Liverpool, in partnership with Johnson Matthey PLC and Loughborough University is making significant progress in the development of stable and practical electrolytes for lithium-oxygen batteries.