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Chemists found an effective remedy for "aged" brain diseases
Scientists synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer's, Parkinson's, and other severe brain pathologies.
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Deconstructing the infectious machinery of SARS-CoV-2
Scientists from three national labs have published a comprehensive study that - alongside other recent, complementary studies of coronavirus proteins and genetics - represents the first step toward developing treatments for COVID-19.
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COVID-19 made unequal access to food worse, study suggests
When COVID-19 hit, affluent Columbus residents responded by taking significantly fewer trips to large grocery and big-box stores, apparently ordering more online and stocking up when they did go out to shop.With fewer options available to them, low-income people had to double down on what they had always done: regular trips to the local dollar stores and small groceries to get their family's food.
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Personalized immunotherapy response studied in body-on-a-chip cancer models
Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer,
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COVID-19 antibodies persist at least nine months after infection
Testing of an entire Italian town shows antibody levels remain high nine months after SARS-CoV-2 infection, whether symptomatic or asymptomatic.
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Bonding's next top model -- Projecting bond properties with machine learning
Researchers from The University of Tokyo Institute of Industrial Science have developed a machine learning-based model to predict the characteristics of bonded systems. Using the density of states of the individual component reactants, they have achieved accurate predictions of the binding energy, bond length, number of covalent electrons, and Fermi energy. The broadly applicable model is expected to make a significant contribution to the development of materials such as catalysts and nanowires.
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Why identical mutations cause different types of cancer
Why do alterations of certain genes cause cancer only in specific organs of the human body? Scientists at the German Cancer Consortium (DKTK), the Technical University of Munich (TUM), and the University Medical Center Göttingen have now demonstrated that cells originating from different organs are differentially susceptible to activating mutations in cancer drivers.
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More bullying of LGBTQ+ students in politically conservative districts
Students who identify as LGBTQ+ in Washington state school districts with conservative voting records reported experiencing more bullying than their peers in more politically liberal areas, according to a new study.
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Mathematical models and computer simulations are the new frontiers in COVID-19 drug trials
Researchers are using computer models to simulate COVID-19 infections on a cellular level which allows for virtual trials of drugs and vaccines, opening the possibility of pre-assessment for drug and vaccine efficacy against the virus.
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New alpine moth solves a 180-year-old mystery
Butterflies and moths are among the most diverse animal groups. Scientists have found as many as 5,000 species from the Alps alone. Having been a place of intensive research for 250 years, it is considered a sensation if a new species is discovered from the mountain range these days. This was the case when a Swiss-Austrian team of researchers described a new species of alpine moth in the peer-reviewed journal Alpine Entomology.
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Oncotarget: Biomechanics in response to drug in hypoxia by atomic force spectroscopy
These Oncotarget results show that a degree of chemotherapeutic drug effects on biomechanical and biophysical properties of cancer cells is distinguishable in normoxia and hypoxia`
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Oncotarget: Caspase-11 and AIM2 inflammasome involved in COPD and lung adenocarcinoma
The Oncotarget authors found that AIM2 inflammasome is at the crossroad between COPD and lung cancer in that its higher presence is correlated to lower survival rate of smoking COPD adenocarcinoma patients.
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Oncotarget: Cutaneous apocrine sweat gland carcinoma
Together these Oncotarget results describe the first ever CAC case with a BRCAness genetic background.
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Discrimination and safety concerns barriers to accessing healthy food for food-insecure young adults
University of Minnesota School of Public Health researchers recently completed a study to determine how food-insecure young (emerging) adults (18-29 years of age) adapted their eating and child feeding behaviors during the COVID-19 pandemic. The researchers also sought to identify barriers to food access and opportunities to improve local access to resources for emerging adults. Their study results are published in the Journal of the Academy of Nutrition and Dietetics.
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Preparing for the next pandemic: Harmonize vaccinations in Canada
To prepare for the next pandemic and provide a coordinated approach to vaccination across the country, Canada should create Canadian Immunization Services based on the Canadian Blood Services model, authors propose in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.210670.
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Three key habitat-building corals face worrying future due to climate crisis
The climate crisis will lead to changes in distribution and habitat loss of stony corals in the tropical Atlantic, shows a new study published by the open access publisher Frontiers. The loss of such coral species could have devastating consequences for the marine ecosystems they inhabit. The results of the study highlight an urgent need for coral reef management in the Atlantic.
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Words matter: Language can reduce mental health and addiction stigma, NIH leaders say
In a perspective published in Neuropsychopharmacology, leaders from the National Institutes of Health address how using appropriate language to describe mental illness and addiction can help to reduce stigma and improve how people with these conditions are treated in health care settings and throughout society. The authors define stigma as negative attitudes toward people that are based on certain distinguishing characteristics.
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A bug's life: Millimeter-tall mountains on neutron stars
New models of neutron stars show that their tallest mountains may be only fractions of millimetres high, due to the huge gravity on the ultra-dense objects. The research is presented today at the National Astronomy Meeting 2021.
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Researchers reveal pathogenesis and therapeutic strategy of pre-engraftment syndrome
Researchers revealed the pathological mechanism of severe pre-engraftment syndrome (PES) after umbilical cord blood transplantation, not only providing a treatment strategy for patients with PES, but significantly guiding for further improvement in the curative effect of unrelated cord blood transplantation (UCBT).
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New long-term satellite analysis shows "plum" rainy season wetter now than ever before
Tokyo, Japan - Researchers from Tokyo Metropolitan University have analyzed long-term precipitation radar data from satellites and found significantly enhanced rainfall over the most recent decade during the annual Meiyu-Baiu rainy season in East Asia. The data spans 23 years and gives unprecedented insight into how rainfall patterns have changed. They showed that the increased rainfall was driven by the decadal increased transport of moisture from the tropics and frequent occurrence of the upper tropospheric trough over the front.
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