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Detailed and extensive genome sequencing of a subspecies of rat-infecting malaria parasites should instruct human malaria research.

As more dissolved organic matter enters lakes across the northeast United States, darkening the lakes in a phenomena called 'browning,' new research shows that these waters may be growing less productive and able to sustain less life.

Cynthia A. Stuenkel, MD, clinical professor of medicine at University of California San Diego School of Medicine, and JoAnn E. Manson, MD, DrPH, professor of epidemiology at Harvard T.H. Chan School Of Public Health, review 50 years of progress in women's health in a perspective article publishing the New England Journal of Medicine.

Researchers from Tokyo Metropolitan University have enhanced "super-resolution" machine learning techniques to study phase transitions. They identified key features of how large arrays of interacting "particles" behave at different temperatures by simulating tiny arrays before using a convolutional neural network to generate a good estimate of what a larger array would look like using "correlation" configurations. The massive saving in computational cost may realize unique ways of understanding how materials behave.

The average IQ of adults who were born very preterm (VP) or at a very low birth weight (VLBW) has been compared to adults born full term by researchers from the Department of Psychology at the University of Warwick. Researchers have found VP/VLBW children may require special support in their education to boost their learning throughout childhood.

Corals that withstood a severe bleaching event and were transplanted to a different reef maintained their resilient qualities, according to a new study led by Katie Barott of the University of Pennsylvania.

Among individuals with healthy kidneys, those with more frequent depressive symptoms were more likely to show signs of rapid kidney function decline over a median follow-up of 4 years.

A breakthrough study by Bryan Shaw, Ph.D., professor of chemistry and biochemistry at Baylor University, aims to make science more accessible to people who are blind or visually impaired through small, candy-like models.

The Geological Society of America regularly publishes articles online ahead of print. For April, GSA Bulletin topics include multiple articles about the dynamics of China and Tibet; new insights into the Chicxulub impact structure; and the dynamic topography of the Cordilleran foreland basin. You can find these articles at https://bulletin.geoscienceworld.org/content/early/recent.

A team at Washington University in St. Louis has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely control motor activity without surgical device implantation.

"Our results support the idea that walking may have a beneficial effect on bowel function," said Dr. Gorman at the University of Maryland. Subjects in the exoskeletal-assisted walking program saw some improvement in bowel function compared to a control group. "We saw a notable reduction in bowel evacuation time, with 24 percent of participants reporting an improved experience," said Dr. Forrest at Kessler Foundation. "Also, participants' stools trended toward better consistency, supporting our hypothesis that this intervention may improve several measures of bowel function."

A study of gene activity in the brain's hippocampus, led by UT Southwestern researchers, has identified marked differences between the region's anterior and posterior portions. The findings, published today in Neuron, could shed light on a variety of brain disorders that involve the hippocampus and may eventually help lead to new, targeted treatments.

UC San Diego scientists have developed a genetics toolkit that helps pave the way to a gene drive designed to stop Culex mosquitoes from spreading disease. Much less studied than other genera, Culex mosquitoes spread devastating afflictions stemming from West Nile virus, Japanese encephalitis virus and the pathogen causing avian malaria.

Centuries-old smoke particles preserved in the ice reveal a fiery past in the Southern Hemisphere and shed new light on the future impacts of global climate change.

A new study of dozens of wild fish species commonly consumed in the Peruvian Amazon says that people there could suffer major nutritional shortages if ongoing losses in fish biodiversity continue. Furthermore, the increasing use of aquaculture and other substitutes may not compensate.

A study coordinated by Luís Graça, principal investigator at the Instituto de Medicina Molecular (iMM; Portugal) used lymph nodes, tonsils and blood, to show how the cells that control production of antibodies are formed and act. The results published now in the scientific journal Science Immunology unveiled key aspects about the regulation of antibody production, with significant importance for diseases where antibody production is dysregulated such as autoimmune diseases or allergies.

A team of researchers offer new insight on conversion factors of greenhouse gases into their CO2 equivalent. The publication in Science Advances puts forward the economic benefits of reassessing periodically conversion factors according to scenarios of global warming.

Older adults with cerebral palsy are more likely to have debilitating musculoskeletal conditions, but our researchers found they receive significantly less physical therapy for those ailments. The lead author says the results, while staggering, support their hypothesis that people with CP receive inequitable health care.

"This is particularly exciting because therapy using robotic exoskeletons shows such promise for improving the lives of people with co-occurring mobility and cognitive disability, a cohort that likely has the greatest potential to benefit from this new technology," said Dr. Androwis at Kessler Foundation. "We're eager to design a larger trial to further study these effects. Based on our initial results, we're optimistic that this approach may be superior to the current standard of care."

A small molecule STING agonist was highly protective against the virus that causes COVID-19 and likely other coronaviruses