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Targeted delivery of therapeutic RNAs only to cancer, no harm caused to healthy cells

Eurekalert - Jun 29 2021 - 00:06
The groundbreaking technology may revolutionize the treatment of cancer and a wide range of diseases and medical conditions.
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Diversity of tiny bobtail squid driven by ancient biogeographic events, finds new study

Eurekalert - Jun 29 2021 - 00:06
Researchers took a close look at bobtail and bottletail squids to establish their evolutionary relationships and the timing of the divergence of different species.
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Stopping the sulfur shuttle for better batteries

Eurekalert - Jun 29 2021 - 00:06
A layer of hierarchically three-dimensional porous graphene greatly suppresses a problem holding back the development of lithium-sulfur batteries.
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Success in reversing dementia in mice sets the stage for human clinical trials

Eurekalert - Jun 29 2021 - 00:06
Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer's disease, but also reverse the effects of the disorders.
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Nanoscale thermoplasmonic heating shows promise for studies of nanomaterials

Eurekalert - Jun 29 2021 - 00:06
Due to plasmon resonance, the electric field near a metal nanoparticle can be enhanced by tens and hundreds of times. This means that such nanostructures function as optical nanoantennas that enhance the light-matter interaction.
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Using artificial intelligence to overcome mental health stigma

Eurekalert - Jun 29 2021 - 00:06
Researchers from University of Tsukuba have developed an artificial intelligence system that identified signs of mental distress in workers using only sociodemographic, lifestyle, and sleep data. The predictions made by the system were comparable to those made by a team of psychiatrists. Such systems may be helpful for identifying signs of depression in individuals who may be hesitant to report subjective feelings of distress as a result of mental health stigma.
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To adsorb or to do not adsorb? That is the question

Eurekalert - Jun 29 2021 - 00:06
Prolonged exposure to antibiotics leads to the gain of bacteria's ability to defeat the drugs designed to fight them. Thus, if such antibiotic-resistant bacteria cause the infection, the only chance to use a specialized virus called phage infecting specific bacteria species. It is a powerful weapon against deadly diseases. At the same time, the effective treatment depends on factors that would not be suspected for years to impact the successful therapy.
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What makes vets feel good at work?

Eurekalert - Jun 29 2021 - 00:06
Receiving a simple thank you, spending time with peers and further developing their expertise, are all factors that make veterinarians feel good at work, according to a new study by researchers at the University of Adelaide.
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DNA barcodes decode the world of soil nematodes

Eurekalert - Jun 29 2021 - 00:06
Toyohashi University of Technology used a next-generation sequencer to develop a highly efficient method to analyze soil nematodes by using the 18S ribosomal RNA gene regions as DNA barcodes. They successfully used this method to reveal characteristics of nematode communities. The target will be expanded to cover all soil-dwelling organisms in agricultural soils to allow investigations into a soil's environment and bio-diversity. This is expected to contribute to advanced agriculture.
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A world first! Visualizing atomic-scale structures with the optical force

Eurekalert - Jun 29 2021 - 00:06
A team of scientists from Osaka University, Osaka Prefecture University, and Nagoya University created three-dimensional maps of the force fields around quantum dots caused by laser light. Using atomic force microscopy with frequency modulation, they were able to achieve spatial resolution of less than one nanometer for the first time. This work may greatly advance the fields of nanotechnology and photocatalysis.
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AAFP releases updated feline senior care guidelines to the veterinary community

Eurekalert - Jun 29 2021 - 00:06
The American Association of Feline Practitioners (AAFP) has released the updated 2021 AAFP Feline Senior Care Guidelines to be published in the July issue of the Journal of Feline Medicine and Surgery. This update provides emerging advances in feline medicine with respect to the aging cat. The Task Force of experts provides a thorough current review in feline medicine that emphasizes the individual senior patient.
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Cell-based immunotherapy shows promise against melanoma

Eurekalert - Jun 29 2021 - 00:06
Researchers at Washington University School of Medicine in St. Louis have shown in preclinical studies conducted in mice and human cells that a type of immunotherapy based on natural killer cells could be effective against solid tumors, starting with melanoma, a type of skin cancer that can be deadly if not caught early.
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Mongoose in the city: How landscape can impact disease transmission in Botswana

Eurekalert - Jun 29 2021 - 00:06
"The question has always been how do we predict what's going to happen once an infectious disease emerges," said Kathleen Alexander, the William E. Lavery Professor in the Department of Fish and Wildlife Conservation. "By using systems that are tractable, we can begin to learn a lot more about how disease dynamics are shaped by host behavior and environmental drivers, including urbanizing landscapes."
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Looking at tumors through a new lens

Eurekalert - Jun 29 2021 - 00:06
Neoadjuvant immune checkpoint blockade is a promising treatment for melanoma and other cancer types, and has recently been shown to provide a modest survival benefit for patients with recurrent glioblastoma. To improve the treatment efficacy, researchers are looking for vulnerabilities in surgically removed glioblastoma tissues, but this has been difficult due to the vast differences within the tumor and between patients. To address this challenge, ISB researchers and their collaborators developed a new way to study tumors.
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Collaborative care effective for pain, depression and anxiety

Eurekalert - Jun 29 2021 - 00:06
Chronic pain, depression, anxiety, and other symptom-based conditions are growing in prevalence. Regenstrief Institute Research Scientist Kurt Kroenke, M.D., writes in the Journal of General Internal Medicine how collaborative care can and should play a major role targeting the treatment of symptoms and functional decline, both too frequently marginalized in medically oriented care delivery.
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UofL researchers lead call to increase genetic diversity in immunogenomics

Eurekalert - Jun 29 2021 - 00:06
Historically, most large-scale immunogenomic studies - those exploring the association between genes and disease - were conducted with a bias toward individuals of European ancestry. Corey T. Watson, Ph.D., assistant professor in the University of Louisville Department of Biochemistry and Molecular Genetics, is leading a call to actively diversify the genetic resources he and fellow immunogenomics researchers use in their work to advance genomic medicine more equitably.
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The final dance of mixed neutron star-black hole pairs

Eurekalert - Jun 29 2021 - 00:06
Another missing piece has just been added to our knowledge of cosmic phenomena. The LIGO, Virgo and KAGRA collaborations have announced the first detection of gravitational waves resulting from the 'mixed' merger between a black hole and a neutron star. The discovery, published on June 29, 2021 in Astrophysical Journal Letters, involves CNRS researchers working within the Virgo scientific collaboration.
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Astrophysicists detect first black hole-neutron star mergers

Eurekalert - Jun 29 2021 - 00:06
Discovered by an international team of astrophysicists including Northwestern University researchers, two events -- detected just 10 days apart -- mark the first-ever detection of a black hole merging with a neutron star. The findings will enable researchers to draw the first conclusions about the origins of these rare binary systems and how often they merge.
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LIGO-Virgo-KAGRA finds elusive mergers of black holes with neutron stars

Eurekalert - Jun 29 2021 - 00:06
For the first time, researchers have confirmed the detection of a collision between a black hole and a neutron star. In fact, the scientists detected not one but two such events occurring just 10 days apart in January 2020.
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Air pollution from wildfires impacts ability to observe birds

Eurekalert - Jun 29 2021 - 00:06
Researchers from the University of Washington provide a first look at the probability of observing common birds as air pollution worsens during wildfire seasons. They found that smoke affected the ability to detect more than a third of the bird species studied in Washington state over a four-year period. Sometimes smoke made it harder to observe birds, while other species were actually easier to detect when smoke was present.
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