Feed aggregator

A research team at the MDC has succeeded in tracking genes through space and time within a one-cell zebrafish embryo - even before cell division occurs. They have now described a method in the journal "Nature Communications" that may one day allow scientists to measure cell response to drugs, for example, in organoids.

The University of North Florida archaeology team is now fairly confident they have located the lost Indigenous northeast Florida community of Sarabay, a settlement mentioned in both French and Spanish documents dating to the 1560s but had not been discovered until now.

Trends in heat discomfort are more subtle than expected across Saudi Arabia and beyond.

Variations in children's speech has traditionally been attributed to developmental delays. Recent work suggests the reasons for variability are not so clear, and an immediate call for treatment may need to be reconsidered. During the 180th ASA Meeting, Margaret Cychosz from the University of Maryland will discuss the need to better understand these variations. Her presentation, 'Reconsidering variability in child speech production,' will take place Tuesday, June 8.

During the COVID-19 pandemic, some smokers have increased their use of cigarettes while others have quit. Those who believed that smoking increases the risk of getting COVID-19 or having a more severe case were more likely to quit, while those who perceived more stress tended to increase their smoking.

In a first-of-its-kind study, researchers used smart watches and a dedicated app to monitor 169 subjects before and during Israel's second COVID-19 lockdown (October 2020).

Produced in a sustainable way, synthetic fuels contribute to switching mobility to renewable energy and to achieving the climate goals in road traffic. In Empa's mobility demonstrator, move, researchers are investigating the production of synthetic methane from an energy, technical and economic perspective - a project with global potential.

Israeli researchers have found that "promiscuous", or multiple-host, viruses utilize significantly non-optimal codons (the DNA sequences which encode amino acids of the protein) compared to single-host viruses. All of the coronaviruses adopt non-optimal codons to infect multiple hosts. However, instead of being weakly expressed, coronaviruses proteins have been observed to be highly expressed. This effect is provided by a special "trick" of coronaviruses which mitigate degradation which dramatically increase their viral mRNA load during infections.

Rising unemployment, inadequate benefits and low paid work are the main causes of poverty and destitution in Stoke-on-Trent according to the findings of a new study.

Which are the most compelling success factors of a large-scale Agile software transformation? And how do these factors relate? A new long-term study from Aalborg University highlights the stakeholders' roles in such transformations. The main result is a valuable model for software managers to set up and effectively manage the transformation of organisations.

A study by RCSI indicates that exercise is probably the most effective short-term treatment for depression in people with coronary heart disease, when compared to antidepressants and psychotherapy or more complex care.

When it comes to climate change, policymakers may fail to see the trees for the forest. Turns out that the trees may be the answer after all, according to a study published by authors from more than seven countries on June 3 in Nature Climate Change.

A multidisciplinary team led by researchers from the Spanish Research Council (CSIC) identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy. The study, published in Cell Reports, identifies cell-type specific transcriptional signatures of hyper-excitability and neurodegeneration, providing grounds for improved diagnosis.

Researchers at Boston Children's Hospital, working in collaboration with Pfizer, now report a high-throughput target and drug discovery platform using motor neurons made from ALS patients. Using the platform, they confirmed two known targets and identified an existing class of drugs -- agonists to the dopamine D2 receptor -- as potential novel treatments.

Researchers find that age-adjusted mortality rates (AAMRs) declined in both rural and urban populations, but that the gap between the death rates dramatically widened as white individuals aged 25 to 64 in rural areas faced increasing AAMRs.

Decisions made now will determine whether economies win or lose money as the coal industry changes over the next couple of decades.

The benefits of routine primary care doctor visits include chronic illness detection, cancer screenings and therefore should continue, despite some calls from healthcare leaders saying they're a waste of time. For at-risk populations, the check-ups are still vital, and all patients on Medicare and many insured patients pay $0 copay for annual wellness checks.

Researchers found differences in sociodemographic and clinical characteristics by entry location for SARS-CoV-2 testing within a safety-net health system. White and English-speaking individuals disproportionately initiated testing via telehealth visits, while black, Native American and non-English-speaking patients disproportionately initiated testing through the emergency department. 

This study tracked COVID-19 outcomes for 543 individuals with intellectual and developmental disabilities who were receiving support services from an organization providing residential services in the five boroughs of New York.

What The Study Did: The findings of this observational study of the association of race/ethnicity with COVID-19 infection rates and the interaction of pre-COVID experiences of food insecurity suggest that the association varied over time and across racial/ethnic groups.