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Blood stem cells make brain tumors more aggressive
Blood stem cells make brain tumors more aggressiveFor the first time, scientists from the German Cancer Consortium (DKTK) partner site in Essen/Düsseldorf have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These hematopoietic stem cells promote division of the cancer cells and at the same time suppress the immune response against the tumor. This surprising discovery might open up new possibilities for developing more effective immunotherapies against these malignant brain tumors.
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Deep machine learning completes information about the bioactivity of one million molecules
- A tool developed by the Structural Bioinformatics and Network Biology lab at IRB Barcelona predicts the biological activity of chemical compounds, key information to evaluate their therapeutic potential.- Using artificial neural networks, scientists have inferred experimental data for a million compounds and have developed a package of programs to make estimates for any type of molecule.- The work has been published in the journal Nature Communications.
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Striking gold: Synthesizing green gold nanoparticles for cancer therapy with biomolecules
Scientists at Tokyo Institute of Technology (Tokyo Tech) have designed an eco-friendly protocol for synthesizing gold nanoparticles with optimized morphology for near-infrared light absorption using a biomolecule called B3 peptide. In their paper, they report the synthesis of triangular and circular gold nanoplates and their effectiveness in killing cancer cells by converting the absorbed light into heat, providing useful insights for the development of non-invasive cancer therapy.
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HKUST scientists develop simple blood test for early detection of Alzheimer's disease
An international research team led by HKUST has developed a simple but robust blood test from Chinese patient data for early detection and screening of Alzheimer's disease (AD) for the first time, with an accuracy level of over 96%.
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New tools for pandemic prevention research: DNA sequencing from water and leech
In a new scientific investigation headed by the German Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), water from African and Mongolian waterholes as well as bloodmeals from Southeast Asian leeches were assessed for the ability to retrieve mammalian viruses without the need to find and catch the mammals. The scientists analysed the samples using high throughput sequencing to identify known viruses as well as viruses new to science.
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Sunflower peptide as 'template' for potential analgesic
A naturally occurring peptide in sunflower seeds was synthetically optimised and has now been identified as a potential drug for treating abdominal pain or inflammation (in the gastrointestinal tract, abdominal area and/or internal organs).
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Honey, we shrunk the intense XUV laser
An international team of researchers has demonstrated a new concept for the generation of intense extreme-ultraviolet (XUV) radiation by high-harmonic generation (HHG). Its advantage lies in the fact that its footprint is much smaller than currently existing intense XUV lasers. The new scheme is straightforward and could be implemented in many laboratories worldwide, which may boost the research field of ultrafast XUV science. The detailed experimental and theoretical results have been published in Optica.
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Human 'time neurons' encode specific moments in time
Neurons in the hippocampus fire during specific moments in time, according to research recently published in JNeurosci. The cells may contribute to memory by encoding information about the time and order of events.
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Transforming the layered ferromagnet F5GT for future spintronics
An Australian-Chinese collaboration achieves record-high electron doping in a layered ferromagnet, causing magnetic phase transition--with significant promise for future electronics. Control of magnetism by electric voltage is vital for developing future, low-energy high-speed nano-electronic and spintronic devices, such as spin-orbit torque devices and spin field-effect transistors.
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An atlas of the bumblebee brain
A three-dimensional atlas of the bumblebee brain is now available. It will allow to even better research how nerve cells are interconnected and how they process information.
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A template for fast synthesis of nanographenes
Development of a new APEX reaction means that large numbers of nanographenes can be easily synthesized using a commercially available hydrocarbon as a template.
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A way to surmount supercooling
Osaka University researchers study the use of nanoparticles to induce crystallization of supercooled aqueous solutions to clathrate hydrates. On the basis of scanning electron microscopy images, they discovered that silver nanoparticles are much more effective compared with palladium or gold. This research may open the way for new latent heat energy storage materials via enhanced supercooling control.
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Researchers are using photos of toasters and fridges to train algorithms to detect COVID
New research using machine learning on images of everyday items is improving the accuracy and speed of detecting respiratory diseases, reducing the need for specialist medical expertise.Edith Cowan University (ECU) researchers trained algorithms on a database of more than 1 million commonplace images and transferred this knowledge to identify characteristics of medical conditions which can be diagnosed with an x-ray.
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Advanced care: Smart wound dressings with built-in healing sensors
New type of multifunctional wound dressings feature glowing nanosensors to track and monitor for infection. Harnessing the antimicrobial and anti-inflammatory power of magnesium hydroxide, the smart dressings can also fight bacteria and reduce inflammation to help promote healing.
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Boring to study slow earthquakes
Slow earthquakes are long-period earthquakes that are not so dangerous alone, but are able to trigger more destructive earthquakes. Their origins lie in tectonic plate boundaries where one plate subsides below another. Though the causal mechanism is already known, there has been a lack of data to accurately model the life cycle of slow earthquakes. For the first time, researchers use deep-sea boreholes to gauge pressures far below the seafloor.
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Underground fiber optic sensors record sounds of COVID lockdown, reopening
In March 2020, daily life in the United States changed in an instant as the country locked down to deal with the initial wave of the COVID-19 pandemic. New research reveals how residents in one community returned to their routines as the restrictions lifted, according to a team of Penn State scientists.
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Gene discovery may hold key to better therapies for OCD
Columbia research finds that some cases of OCD are caused by damaging gene variants that, while rare, provide a needed starting point for the development of better therapeutics.
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New, third type of supernova observed
An international team including astronomers from UC Davis has observed the first example of a new type of supernova. The discovery, confirming a prediction made four decades ago, could lead to new insights into the life and death of stars.
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Virtual reality boosts brain rhythms crucial for neuroplasticity, learning and memory
A new discovery in rats shows that the brain responds differently in immersive virtual reality environments versus the real world. The finding could pave the way for "virtual reality therapy" for learning and memory-related disorders ranging including ADHD, autism, Alzheimer's disease, epilepsy and depression.
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Engineered yeast probiotic developed to treat inflammatory bowel disease
Researchers from Brigham and Women's Hospital have developed a "designer" probiotic -- a thoughtfully engineered yeast that can induce multiple effects for treating IBD.
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