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Research at Baylor College of Medicine, the Texas Heart Institute and collaborating institutions is moving a novel promising gene therapy to treat heart failure closer to the clinic.

Grieving friends and relatives from ethnic minority backgrounds are suffering from a lack of appropriate help to cope with the loss of a loved one, especially during the COVID-19 pandemic. Researchers say people representing those communities need to be involved when services are developed and delivered to ensure that groups get the support they need.

A new study published in PLOS ONE reports genetic and oxygen and strontium isotopic data for individuals buried at Alalakh, finding little evidence for the foreigners mentioned in texts.

A new study based on computational analyses of how SARS-CoV-2 interacts with host cell proteins has identified 200 previously approved drugs that could be repurposed to treat COVID-19, 40 of which have already entered clinical trials.

A Rutgers-led team of researchers has developed a microchip that can measure stress hormones in real time from a drop of blood.

Engineers have developed a sweat-proof "electronic skin" -- a conformable, sensor-embedded sticky patch that reliably monitors a person's health, even when a wearer is perspiring. The patch contains artificial sweat ducts through the material's ultrathin layers.

When we look at a visual stimulus, it drives a cascade of neural activity from low-level to higher level visual brain areas. The higher areas also provide feedback to the lower areas, where figures elicit more activity than the background. Researchers from the Netherlands Institute of Neuroscience (NIN) now showed that feedback causes the extra neuronal activity in low-level areas and that the extra activity is essential for figure-ground perception.

Researchers have developed and successfully demonstrated a novel method for studying how cells repair damaged DNA in space. Sarah Stahl-Rommel of Genes in Space and colleagues present the new technique in the open-access journal PLOS ONE on June 30, 2021.

In the German population, a surprisingly high 6% of under-18s are at risk of cognitive decline, falls and more from the cumulative effect of anticholinergic medications such as antihistamines and antidepressants.

The deep sea Pacific Salas y Gómez and Nazca ridges are highly biodiverse and host unique fish and invertebrate taxa, according to video surveys.

A city's street names can provide a glimpse into its cultural value system and a way to quantify cultural indicators, according to a study published June 30, 2021 in the open-access journal PLOS ONE by Melanie Bancilhon from Washington University in Saint Louis, US, and colleagues.

Magnetic resonance imaging (MRI) is widely used in medicine to detect, diagnose and treat diseases such as cancer, while relying on experts' interpretation of images. Quantitative MRI, which obtains numerical measurements during the scans, can now potentially offer greater accuracy, repeatability and speed -- but rigorous quality control is needed for it to reach its full potential, according to a new study.

New research from the University of Georgia shows that there may be more antimicrobial-resistant salmonella in our food animals than scientists previously thought.

Cancer cells can put the body's immune cells into sleep mode. Immunotherapy can reverse this, but it doesn't work for all patients and all cancer types. Researchers at TU/e have developed machine learning models that can predict if someone is likely to respond positively to immunotherapy. In clinical settings, this could pave the way for personalized immunotherapy approaches for patients, as well as guidance on how to best combine immunotherapy with other treatments.

Research by Salk Institute scientists offers a new understanding of how gene activity directs plant growth, and how quickly plants respond to their environment -- with shifting light conditions triggering molecular changes in as little as five minutes. The findings provide insights into how to increase yield and safeguard world food production as climate change shrinks the planet's arable land.

Pick up any product in just about any store and you're likely to find information that indicates the country of origin of the product. The U.S. Federal Trade Commission (FTC) requires this for any imported product, but not for products made in the United States. When you see the words 'Made in USA' on a product, it's purely for marketing purposes. So, does it work?

GSA's dynamic online journal, Geosphere, posts articles online regularly. Locations and topics studied this month include the central Appalachian Mountains; fossil pollen in Colombia; the precision and accuracy of model analyses; the Bone Spring Formation, Permian Basin, west Texas; and the geochronology of modern river sediment in south-central Alaska.

The July edition of SLAS Discovery is a Special Edition featuring the cover article, "Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry" by Lesley-Anne Pearson, Charlotte J. Green, Ph.D., De Lin, Ph.D., Alain-Pierre Petit, Ph.D., David W. Gray, Ph.D., Victoria H. Cowling, Ph.D., and Euan A. F. Fordyce, Ph.D., (Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK).

Researchers have developed a software tool that identify the regulators of genes. The system leverages a machine learning algorithm to predict which transcription factors are most likely to be active in individual cells.

The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98% sensitivity if deployed at least every three days.