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Newly discovered genetic variants in a single gene cause neurodevelopmental disorder

Eurekalert - Jul 01 2021 - 00:07
Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with conditions that affect how the brain functions.
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Rewiring the adult brain — Scanning the mind of a blind ‘Batman’ reveals that novel maps can emerge in the adult brain

Eurekalert - Jul 01 2021 - 00:07
The adult brain is more malleable than previously thought, according to researchers from IDC Herzliya. They trained a 50-year-old man, blind from birth, to "see" by ear, and found that neural circuits in his brain formed so-called topographic maps - a brain organization previously thought to emerge only in infancy. This finding, reported in Neuroimage, sheds new light on the brain's ability for change and holds promise to restore lost functions, for example, after a stroke
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Antidiabetic drug causes double the weight loss of competitor in Type 2 diabetes patients

Eurekalert - Jul 01 2021 - 00:07
Patients with Type 2 diabetes who were prescribed SGLT2 inhibitors lost more weight than patients who received GLP-1 receptor agonists, according to a University at Buffalo-led study.
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Chasing the cells that predict death from severe COVID-19

Eurekalert - Jul 01 2021 - 00:07
By studying T cells, a team of scientists at Gladstone Institutes has uncovered fundamental differences between patients who overcome severe COVID-19 and those who succumb to it. The team also found that dying patients harbor relatively large numbers of T cells able to infiltrate the lung, which may contribute to the extensive lung deterioration that is a hallmark of fatal COVID-19.
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Novel microscopy method at UT Southwestern provides look into future of cell biology

Eurekalert - Jul 01 2021 - 00:07
What if a microscope allowed us to explore the 3D microcosm of blood vessels, nerves, and cancer cells instantaneously in virtual reality? What if it could provide views from multiple directions in real time without physically moving the specimen and worked up to 100 times faster than current technology?
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Scientists reveal a new therapeutic vulnerability in pancreatic cancer

Eurekalert - Jul 01 2021 - 00:07
Reducing levels of a hormone prevented metastasis and prolonged survival in mice with pancreatic cancer, a study from Columbia has found, which could lead to new treatments for patients.
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Better predicting how plants and animals will weather climate extremes

Eurekalert - Jul 01 2021 - 00:07
A team of scientists has devised a more accurate way to predict the effects of climate change on plants and animals -- and whether some will survive at all.
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Unlocking the power of the microbiome

Eurekalert - Jul 01 2021 - 00:07
Not only animals and humans host a complex community of microorganisms -- plants do this as well. Researchers at ETH Zurich have recently published two new studies that shed light on fundamental aspects of these close -- and often overlooked -- relationships.
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New chatbot can explain apps and show you how they access hardware or data

Eurekalert - Jul 01 2021 - 00:07
Researchers at Aalto University have harnessed the power of chatbots to help designers and developers develop new apps and allow end users to find information on the apps on their devices. The chatbot 'Hey GUI' can answer questions by showing images and screenshots of apps, or through simple text phrases.
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Astonishing altitude changes in marathon flights of migratory birds

Eurekalert - Jul 01 2021 - 00:07
Extreme differences in flight altitude between day and night may have been an undetected pattern amongst migratory birds -- until now. The observation was made by researchers at Lund University in Sweden in a study of great snipes, where they also measured a new altitude record for migratory birds, irrespective of the species, reaching 8,700 meters.
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Fibromyalgia likely the result of autoimmune problems

Eurekalert - Jul 01 2021 - 00:07
New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London, in collaboration with the University of Liverpool and the Karolinska Institute, has shown that many of the symptoms in fibromyalgia syndrome (FMS) are caused by antibodies that increase the activity of pain-sensing nerves throughout the body.The results show that fibromyalgia is a disease of the immune system, rather than the currently held view that it originates in the brain.
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SARS-CoV-2 replication targets nasal ciliated cells early in COVID-19 infection

Eurekalert - Jul 01 2021 - 00:07
SARS-CoV-2 replication targets nasal ciliated cells early in COVID-19 infection. The establishment of nasal mucosal immunity against SARS-CoV-2 through a nasal vaccine could be the most efficient way to combat COVID-19 infection.
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Study identifies risk factors for severe COVID-19 in individuals with sickle cell disease

Eurekalert - Jul 01 2021 - 00:07
New research published today in the journal Blood Advances finds that certain factors, such as a history of severe pain episodes and coexisting organ conditions, increase the risk of severe COVID-19 illness, including hospitalization, in individuals living with sickle cell disease (SCD). According to researchers, the study results underscore the need for COVID-19 risk reduction strategies and vaccination for this medically vulnerable population.
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Catalyzing the conversion of biomass to biofuel

Eurekalert - Jul 01 2021 - 00:07
Zeolites are extremely porous materials: Ten grams can have an internal surface area the size of a soccer field. Their cavities make them useful in catalyzing chemical reactions and thus saving energy. An international research team has now made new findings regarding the role of water molecules in these processes. One important application is the conversion of biomass into biofuel.
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G-quadruplex-forming DNA molecules enhance enzymatic activity of myoglobin

Eurekalert - Jul 01 2021 - 00:07
A collaboration led by Distinguished Professor Dr. Kazunori Ikebukuro from Tokyo University of Agriculture and Technology (TUAT), Japan, discovered that G-quadruplex (G4)-forming DNA binds myoglobin through a parallel-type G4 structure. Through the G4 binding, the enzymatic activity of myoglobin increases over 300-fold compared to that of myoglobin alone (Figure). This finding indicates that DNA may work as a carrier of genetic information in living organisms and act as a regulator of unknown biological phenomena.
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New data science platform speeds up Python queries

Eurekalert - Jul 01 2021 - 00:07
Data queries written in Python, a commonly used programming language, can grind data analytics platforms to a crawl, but a new platform developed by researchers from Brown and MIT may finally solve the Python efficiency problem.
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RUDN University chemists synthesize biodiesel from jatropha curcas plant

Eurekalert - Jul 01 2021 - 00:07
RUDN University chemists have proposed a new method of producing fuel from Jatropha Curcas, a poisonous tropical plant. Natural minerals and a non-toxic additive from vegetable raw materials are used for that. The reaction efficiency is 85%. The fuel can be used in diesel internal combustion engines.
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From meadow to plate: The cultured meat that replaces animals with grass

Eurekalert - Jul 01 2021 - 00:07
An affordable lab system that uses grass blades to turn cells into cultured meat, by creating a scaffold that animal stem cells can attach to and grow on, has been developed at the University of Bath in the UK.
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Near-death experiences, a survival strategy ?

Eurekalert - Jul 01 2021 - 00:07
A new study conducted jointly by the University of Copenhagen (Denmark) and the University of Liege (Belgium) and published in Brain Communications shows how near-death experiences in humans may have arisen from evolutionary mechanisms. Researchers attribute for the first time a biological purpose to NDEs.
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A remote laboratory for performing experiments with real electronic and communications equipment

Eurekalert - Jul 01 2021 - 00:07
New research shows that students rate the usefulness and usability of this virtual tool very positively
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