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Panel finds 30-day course of VTE prophylaxis post-discharge improves outcomes
A new set of guidelines, developed by AATS and ESTS (European Society for Thoracic Surgery) presented today at the AATS 101st Annual Meeting, recommends a 30-day course of Venous Thromboembolism (VTE) prophylaxis post-discharge for patients undergoing surgical resection for lung or esophagus cancer. The AATS and ESTS formed a multidisciplinary guideline panel that included broad membership to minimize potential bias when formulating recommendations.
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Modifications to ERATS protocol significantly reduces post-operative opioid usage
A new study, presented today at the AATS 101st Annual Meeting, shows significant reduction in post-operative use of Schedule II opioids for pain management following robotic surgery. To address the on-going issues of opioid overuse and abuse, the study aimed to examine the use of painkillers in Enhanced Recovery After Thoracic Surgery (ERATS) protocols and determine the impact of alternative pain management approaches on clinical outcomes.
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How much does it itch?
Itch can be as debilitating as chronic pain. But it's a hard symptom to measure -- particularly for the 10 million U.S. children with atopic dermatitis, also known as eczema. But now there is a soft, wearable sensor that quantifies itch by measuring scratching when placed on the hand. It allows parents and doctors to track how well itch is being controlled in patients, monitor treatment response and early signs of worsening disease.
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Technology provides non-invasive treatment for congenital heart disease patients
New study results, presented at SCAI 2021, validate the effectiveness of the Medtronic Harmony transcatheter pulmonary valve (TPV) system for patients with congenital heart disease (CHD) and severe pulmonary regurgitation (PR). The Harmony TPV is designed to be a less invasive treatment option for patients with irregularity in their right ventricular outflow tract (RVOT) needing pulmonary valve placement to restore valve function.
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Technology provides procedure efficiencies for congenital heart disease patients
An analysis of a new international registry reveals benefits of using a longer covered stent for interventional procedures in congenital heart disease patients with Sinus Venosus Atrial Septal Defect (SVASD). The study was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2021 Scientific Sessions.
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eNeuro publishes commentaries on upcoming documentary "In Silico"
eNeuro is publishing a special collection of commentaries on April 30, 2021 on the neuroscience documentary In Silico. The collection, titled "Epistemological Lessons from the Blue and Human Brain Projects," features reactions to the documentary from leading neuroscientists as well as a discussion on brain modelling and massive research collaborations in general.
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Wildfire smoke trends worsening for Western US
New research from the University of Utah ties the worsening trend of extreme poor air quality events in Western regions to wildfire activity, with growing trends of smoke impacting air quality clear into September.
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Not just for finding planets: Exoplanet-hunter TESS telescope spots bright gamma-ray burst
NASA has a long tradition of unexpected discoveries, and the space program's TESS mission is no different. SMU astrophysicist and her team have discovered a particularly bright gamma-ray burst using a NASA telescope designed to find exoplanets - those occurring outside our solar system - particularly those that might be able to support life. It's the first time a gamma-ray burst has been found this way.
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Articles for Geosphere posted online in April
GSA's dynamic online journal, Geosphere, posts articles online regularly. Locations and topics studied this month include the Central Anatolian Plateau; the Southern Rocky Mountain Volcanic Field; petrogenesis in the Grand Canyon; and the evolution of the Portland and Tualatin forearc basins, Oregon.
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Engineering T cells to attack cancer broadly
This study builds on decades of work showing that the protein IL-24 attacks cancer broadly, and is the first to deliver the protein using T cells. This approach is in contrast to CAR-T cells, which are built to recognize proteins on the surface of cancer cells and haven't been successful against solid tumors. Mice with prostate cancer experienced shrinkage of the original tumor as well as distant metastases following treatment with IL-24 T cells.
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How to invest in a fairer and low carbon energy system
Governments throughout the world have accelerated their ambitions towards effective climate change mitigation. What is clear, in this challenge of how to tackle the complex and global issue of climate change, is that there is no one technology or stakeholder that will drive the full and timely decarbonisation that the world and its citizens require.
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Factors associated with general surgery residents' operative experience during pandemic
What The Study Did: The association of the COVID-19 pandemic with general surgical residents' operative experience by postgraduate year and case type is examined in this study.
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Simulation of exposure notification cascade for digital contact tracing
What The Study Did: This simulation study estimates key populations and performance indicators along the COVID exposure notification chain of the SwissCOVID digital contact tracing app last year in Zurich, Switzerland.
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US pediatric emergency department visits for mental health conditions during COVID-19 pandemic
What The Study Did: Changes in the demographic characteristics and clinical outcomes of pediatric emergency department visits for mental health conditions during the COVID-19 pandemic are described in this study.
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Integrated cardiothoracic residency continues to be most challenging specialty to match
Research presented today at the AATS 101st Annual Meeting, shows that the six year Integrated Cardiothoracic (CT I-6) residency continues to be the most challenging to match, while the pool of applicants has become more diverse. The study, which aimed to identify applicant characteristics associated with a successful match, used data from the National Residency Matching Program (NRMP), Electronic Residency Application Service (ERAS), and Association of American Medical Colleges (AAMC) for Thoracic Surgery, and other sources.
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Vaccines bring us closer
Effectively and safely protecting against disease--this is what makes vaccines a vital and successful public health tool that saves lives and safeguards health and well-being. Looking at immunisation programmes' successes and remaining challenges, this week's issue of Eurosurveillance is published on the occasion of European Immunization Week (EIW) 2021.
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A milestone in muscular dystrophy therapy
A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders. The ECRC team led by Professor Simone Spuler have published their findings in the journal JCI Insight.
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Researchers analyzed circulating currents inside gold nanoparticles
Researchers in the Nanoscience Center of University of Jyväskylä in Finland and in the Guadalajara University in Mexico developed a method that allows for simulation and visualization of magnetic-field-induced electron currents inside gold nanoparticles. The method facilitates accurate analysis of magnetic field effects inside complex nanostructures in nuclear magnetic resonance measurements and establishes quantitative criteria for aromaticity of nanoparticles. The work was published 30.4.2021 as an Open Access article in Nature Communications.
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CO2 catalysis made more accessible
Many industrial processes emit carbon dioxide into the atmosphere. Unfortunately, however, current electrochemical separation methods are expensive and consume large amounts of power. They also require expensive and rare metals as catalysts. A study in the journal Angewandte Chemie describes a new aerogel electrocatalyst formed from an inexpensive metal alloy, which enables highly efficient electrochemical conversion of carbon dioxide. The main product is formic acid, which is a nontoxic basic chemical.
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Highly efficient photodynamic-immunotherapy by combining AIEgen with Poly(I:C)
The study reports the design and preparation of erythrocyte membrane-bound nanoparticles (M@AP), for tumoral photodynamic-immunotherapy. The M@AP is formed by self-assembly of aggregation-induced emission polymer (AIEgens) (named P2-PPh3) and polyinosinic : polycytidylic (Poly(I:C)), followed by erythrocyte membrane encapsulation. The M@AP nanoparticles combines the PDT properties of the AIE-active polyelectrolyte and immunotherapy properties of Poly(I:C) to achieve synergistic activation of the immune system for anti-tumor activity.
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