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Announcing a new article publication for BIO Integration journal. In this review the authors Muhammad Arif Asghar, Rabia Ismail Yousuf, Muhammad Harris Shoaib, Muhammad Arif Asghar and Nazish Mumtaz from Jinnah Sindh Medical University, Karachi, Pakistan, University of Karachi, Karachi, Pakistan, Food and Marine Resources Research Centre, Pakistan and Benazir Bhutto Shaheed University, Karachi, Pakistan discuss toxicity and challenges in transferability of surface-functionalized metallic nanoparticles from animal models to humans.

Obsessive-compulsive disorder (OCD) in children and adolescents is associated with impaired education and worse general health later in life. Access to specialist treatment is often limited. According to a study from Centre for Psychiatry Research at Karolinska Institutet in Sweden and Region Stockholm, internet-delivered cognitive behavioural therapy (CBT) can be as effective as conventional CBT. The study, published in the prestigious journal JAMA, can help make treatment for OCD more widely accessible.

A new study sets out guidelines to maximize the benefits of reef restoration, not only for the coral ecosystem, but also to protect local communities from coastal flooding. Researchers simulated waves travelling over different reef profiles at various stages of restoration and found that to reduce the risk of flooding, the upper fore reef and middle reef flat, typically characterized by physically-robust coral species, should be targeted for restoration.

If left untreated, gout can cause severe disability. But unlike rheumatoid arthritis, there are only a handful of ways to treat it. Researchers say a combination of two existing drugs disrupts antibody production and doubles treatment efficacy.

A new study from the University of Surrey and University College London has revealed that treatment for heart attacks could be improved thanks to a novel method of evaluating heart function using contrast-based MRI scans.

While video games can be engaging, some have a higher potential of becoming addictive. However, the mechanisms underlying this addiction are difficult to analyze mathematically. Now, researchers from JAIST, Japan apply the concept of "motion in the mind" to investigate the subjective aspects of different games via analogies with physical models of motion. Their findings explain what makes certain videogames more addictive by nature and will help us tailor games better for specific purposes.

Researchers found that the process of activation of stem cells in the brain responsible for the production of neurons (nerve cells) is not random, but coordinated. According to the researchers, these findings are very important for understanding the proper development of the brain. The findings may form the basis for the development of future treatments using brain stem cells, such as for brain cancer, neurodegenerative diseases like Alzheimer's and Parkinson's, and various brain injuries.

In stark contrast to the current prevailing view that extreme El Niño frequency would increase by two-folds in warmer climate, Prof. Luo and his research team found that this view was misled by common biases in CMIP5's projection of the Pacific mean-state change in the future. Results after removing the bias impacts suggest that extreme El Niño frequency would hardly change, highlighting the great impacts of models' biases on the projection of future climate change.

St. Petersburg, like other cities in the Russian Federation, is actively participating in the establishment of the "Smart City" program, which will provide new services for residents of the megalopolis, increasing the safety of citizens. Digital services are essential for such a system. Due to the Internet of Things (IoT) systems, the environment can adapt to the needs of humanity on its own accord. Cybersecurity threats are especially dangerous for such infrastructure.

The most energetic earthquakes occur where oceanic plates submerge beneath continental plates during plate tectonics. Quakes in these subduction zone settings commonly carry the risk of triggering severe tsunamis. But when the earth shook with a moment magnitude of 8.1 near the northern Chilean city of Iquique on 1 April 2014, the resulting tsunami was relatively small. A unique seismological data set, now published by researchers from GEOMAR provides a possible explanation.

Considered extinct as a breeding species in the early 2000s, the Saker Falcon was recovered when the first active nest from the new history of the species in Bulgaria was discovered in 2018, built by two birds that were reintroduced back in 2015. The results of the world's first reintroduction programme for this species are described in detail in the open-access, peer-reviewed Biodiversity Data Journal.

To better understand how PIF proteins affect apical hook development, scientists from the Institute of Botany of the Chinese Academy of Sciences recently investigated their roles in an organ specific manner.

When trauma, illness, or injury causes significant muscle loss, reconstructive procedures for bioengineering functional skeletal muscles can fall short, resulting in permanent impairments. Finding a synergy in the importance of biochemical signals and topographical cues, researchers developed an efficient technique for muscle regeneration and functional restoration in injured rats. They describe results from the technique in Applied Physics Reviews.

Statins are prescribed to less than half of eligible U.S. patients, and a new study shows time of day may affect doctors' likelihood of writing a script

What The Study Did: This global observational study included patients with COVID-19 representing 13 countries and four continents, and its findings suggest neurological manifestations are prevalent among patients hospitalized with COVID-19 and associated with higher in-hospital death.

A paper published today in JAMA Network Open presents early results of the global effort to gather information about the incidence, severity and outcomes of neurological manifestations of COVID-19 disease.

Improved ventilation can lower the risk of transmission of the COVID-19 virus, but large numbers of decades-old public school classrooms lack adequate ventilation systems. A systematic modeling study of simple air cleaners using a box fan reported in Physics of Fluids shows these inexpensive units can greatly decrease the amount of airborne virus in these spaces, if used appropriately.

New study from Joshua Jacobs (Columbia Engineering) and Itzhak Fried (UCLA) demonstrates the existence of phase precession in the human brain for the first time, and show sthat this neural code not only links sequential positions, as in animals, but also abstract progression towards specific goals. Says lead author Salman Qasim, "We were convinced that phase precession held a lot of promise as a widespread neural code that could be used for learning and cognition."

Network scientists from Beijing Normal University and Bar-Ilan University address the effect of team freshness on the originality and multidisciplinary impact of produced work, by systematically investigating prior collaboration relations between team members. Among other things their study, published in Nature Human Behaviour, reveals that papers of fresher teams are significantly more effective than those of older teams in creating studies of higher originality and greater multidisciplinary impact.

YouTube channels run by zoos focus on entertainment over education, according to a new study.