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Hi-CO unravels the complex packing of nucleosomes
Scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) in Japan have developed a technology that produces high-resolution simulations of one of the basic units of our genomes, called the nucleosome. Their findings were published in the journal Nature Protocols and should help improve understanding of how changes in nucleosome folding influence the inner workings of genes.
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Intratumoral SIRPalpha-deficient macrophages activate tumor-specific cytotoxic T cells
In a study that will be published in Nature Communications on May 28, 2021, a research team led by Dr. Yuan Liu from Georgia State University reports that intratumoral SIRPalpha-deficient macrophages activate tumor antigen-specific cytotoxic T cells to eliminate various syngeneic cancers under radiotherapy. Their study identifies SIRPalpha as a master regulator controling macrophage immune responses and has demonstrated that intratumoral injection of SIRPalpha-depleted macrophages combined with local radiation is an effective strategy to treat different tumors
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Featured research from NUTRITION 2021 LIVE ONLINE
Press materials are now available for NUTRITION 2021 LIVE ONLINE, a dynamic virtual event showcasing new research findings and timely discussions on food and nutrition. The online meeting will be held June 7-10, 2021.
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Rush researchers develop new measure of brain health
A new measure of brain health developed by researchers at Rush University Medical Center may offer a novel approach to identifying individuals at risk of memory and thinking problems, according to research results published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association on June 1, 2021.
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Biologists find invasive snails using new DNA-detection technique
Biologists led by the University of Iowa discovered an invasive species of snails in previously unknown locations along the Eastern Seaboard using a new technique that detects traces of DNA left by the aquatic animals. The finding shows the technique, called eDNA, can detect and control incursions by other invasive species.
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Unprecedented data sharing driving new rare disease diagnoses in Europe
Massive data sharing across Europe is boosting efforts to diagnose rare diseases for individuals whose case remains unsolved even after going through advanced expert clinical settings. A new method developed by an international consrortium has resulted in 255 new diagnoses, which is the 'tip of the icerberg'. The findings are an important first step for a European-wide system to facilitate the diagnosis rare diseases, which can be a long and arduous process.
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Lean and mean: Maximizing 5G communications with an energy-efficient relay network
Scientists at Tokyo Institute of Technology have developed a wirelessly powered relay network for 5G systems. The proposed battery-free communication addresses the challenges of flexible deployment of relay networks. This design is both economical and energy-efficient. Such advances in 5G communications will create tremendous opportunities for a wide range of sectors.
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Scientists say active early learning shapes the adult brain
Through the Abecedarian Project, an early education, randomized controlled trial that has followed children since 1971, researchers from Virginia Tech and the University of Pennsylvania have discovered an enhanced learning environment during the first five years of life shapes the brain in ways that are apparent four decades later. The study appears in the June edition of the Journal of Cognitive Neuroscience.
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Light-shrinking material lets ordinary microscope see in super resolution
UC San Diego engineers developed a technology that turns a conventional light microscope into what's called a super-resolution microscope. It improves the microscope's resolution (from 200 nm to 40 nm) so that it can be used to directly observe finer structures and details in living cells.
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Seeds of economic health disparities found in subsistence society
The Tsimane subsistence communities living on the edge of the Bolivian Amazon have less inequality but also fewer chronic health problems linked to the economic disparity of industrialized Western societies. Researchers tracked 13 different health variables across 40 Tsimane communities, analyzing them against individual's wealth and each community's degree of inequality. While some have theorized that inequality's health impacts are universal, researchers found only two robustly associated outcomes: higher blood pressure and respiratory disease.
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Greenhouse gas emissions from reservoirs higher than previously expected
A new study in Global Biogeochemical Cycles shows per-area greenhouse gas emissions from the world's water reservoirs are around 29% higher than suggested by previous studies, but that practical measures could be taken to help reduce that impact.
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Hypertension during pregnancy is associated with increased risk of stroke in offspring
A study in 5.8 million children has found a higher incidence of stroke four decades later in those whose mother had high blood pressure or pre-eclampsia while pregnant. The research is presented at ESC Heart & Stroke 2021, an online scientific conference of the European Society of Cardiology (ESC).
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How were the carbon contents in terrestrial and lunar mantles established?
Carbon degassed from planetary mantles by volcanic activity plays an important role in the planetary surface environment. However, how the carbon content in the Earth's mantle was established is still poorly understood. Here we show that the mantle of planetary embryos may have been nearly saturated with carbon by new high-pressure experiments and pointed out that the carbon solubility of magma is very consistent with the estimated carbon contents in terrestrial and lunar mantles.
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Graphene-based nanozyme helps to detect L-cysteine in serum
Graphene-based materials can be obtained using various reducing agents, many of which are dangerous and toxic chemicals, and the obtained graphene-based materials are prone to aggregation, limiting their practical applications.
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Ganoderic acid increases radiosensitivity of cancer cell
Recently, the research team led by Prof. KONG Lingtao from Institute of Solid State Physics, Hefei Institutes of Physical Science (HFIPS) prepared a highly active single iron atom catalyst (Fe-ISAs@CN) which can activate H2O2 to generate free radicals, achieving rapid removal of sulfadiazine pollutants in aqueous. The relevant results were published in Journal of Colloid and Interface Science.
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Study reveals degradation of antibiotics in water by iron-based fenton catalytic
Recently, the research team led by Prof. KONG Lingtao from Institute of Solid State Physics, Hefei Institutes of Physical Science (HFIPS) prepared a highly active single iron atom catalyst (Fe-ISAs@CN) which can activate H2O2 to generate free radicals, achieving rapid removal of sulfadiazine pollutants in aqueous. The relevant results were published in Journal of Colloid and Interface Science.
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Metamaterial improves sensitivity of infrared absorption spectroscopy 100 times
The joint research team led by Principal Researcher Dr. Joo-Yun Jung of the Nano-Convergence Mechanical Systems Research Division at KIMM and Professor Jongwon Lee of UNIST developed a metamaterial that enhances infrared absorption spectroscopy through 100-fold amplification of detection signals. The proposed metamaterial is a special functional material with vertical nanogaps of a smaller size than infrared wavelength.
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Oncotarget: 1B3 supports strong potential for therapeutic intervention in oncology
'Despite decades of research and an unprecedented advancement of therapeutic options [1], cancer accounts for one in every six deaths worldwide, with ~18,000,000 new cases diagnosed in 2018 and expected to grow to ~30,000,000 by 2040.'
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Getting stoned: Revealing the mysteries of stonefish venom
University of Queensland scientists working to unlock the mysteries Australia's deadly stonefish have made a discovery which could change how sting victims are treated in the future.
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At-the-moment stress for parents during COVID-19 stay-at-home restrictions
New research finds that during COVID-19 stay-at-home orders, parental stress was higher during the workday compared to after the workday and lower during weekends than during weekdays.
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