A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimers disease-like pathology in mice without causing inflammation or significant side effects.
Vaccinated mice generated an immune response to the protein known as amyloid-beta peptide, which accumulates in what are called amyloid plaques in brains of people with Alzheimers. The vaccinated mice demonstrated normal learning skills and functioning memory in spite of being genetically designed to develop an aggressive form of the disease.
Molecular and statistical genetic studies in 15 Finnish families have shown that there is a substantial genetic component in musical aptitude. Musical aptitude was determined using three tests: a test for auditory structuring ability (Karma Music test), and the Seashore pitch and time discrimination subtests.
The study represents the first systematic molecular genetic study that aims in the identification of candidate genes associated with musical aptitude.
TORONTO, Ontario, Canada -- Mayo Clinic pulmonary researchers have designed and tested a new patient education computer program intended to help people with asthma manage their disease. The program allows asthma patients (an estimated 7 percent of the U.S. adult population) to practice making key decisions in a safe, simulated environment.
The Mayo Clinic group will present results of a study assessing users experiences at the American Thoracic Societys 2008 International Conference in Toronto.
Tampa, Fla. (May 19, 2008) The current issue of CELL TRANSPLANTATION (Vol. 17:4) features a number of publications by researchers seeking new ways to treat Parkinsons disease (PD), a neurological disease characterized by muscle rigidity, tremor and slowed physical movements related to insufficient levels of dopamine (DA) in the basal ganglia of the brain, by using primate models to examine the potential therapy role of transplanted cells.
In the first study of its kind, researchers at the Yerkes National Primate Research Center, Emory University, in collaboration with researchers from the Department of Human Genetics at Emory's School of Medicine, have developed the first transgenic nonhuman primate model of Huntington's disease (HD), one of the most devastating human neurodegenerative diseases.
Scientists have developed the first genetically altered monkey model that replicates some symptoms observed in patients with Huntington's disease, according to a new study funded by the National Institutes of Health. Researchers are now able to better understand this complex, devastating and incurable genetic disorder affecting the brain. This advance, reported in the May 18 advance of online publication edition of Nature, could lead to major breakthroughs in the effort to develop new treatments for a range of neurological diseases.
ATS 2008, TORONTO—People with severe obstructive sleep apnea (OSA) on commercial airline flights may have a greater risk of adverse events from cardiac stress than healthy people, according to new research to be presented at the American Thoracic Societys 2008 International Conference in Toronto on Sunday, May 18.
PHILADELPHIA - A poster session presented today by The University of Texas M. D. Anderson Cancer Center at the Oncology Nurses Society 33rd Annual Congress, found that early nursing intervention and implementation of effective strategies can lead to a decrease in the incidence of lymphedema, better management of chronic lymphedema and improved quality of life in breast cancer patients.
CINCINNATI Researchers at Cincinnati Childrens Hospital Medical Center have identified proteins that could be biological markers of non-cancerous tumors that affect peripheral nerves called Neurofibromatosis 1 (NF1), which can change to a highly aggressive cancer called Malignant Peripheral Nerve Sheath Tumors (MPNST). This new finding could help resolve a current lack of reliable ways to diagnose NF1 and MPNST in patients, according to study findings presented May 16 at the annual meeting of the American Society of Pediatric Hematology/Oncology.