Body

Imagine the power of knowing the three-dimensional structures of all proteins. The 3D-structure can provide information about critical protein-protein interactions both from a global perspective as well as all the way down to the level of minuscule molecular and biochemical detail. In much the same way, structural information can reveal a lot about the protein’s evolutionary relationships and functions.

Suspicion and mistrust of Western medicine led Muslim religious leaders in three northern states of Nigeria to call for the 2003 boycott of the national polio vaccine campaign, according to a historical analysis in PLoS Medicine. The boycott led to fresh outbreaks of polio in Nigeria.

Ayodele Samuel Jegede (University of Ibadan, Nigeria), author of the analysis, says that the boycott needs to be considered in its proper historical and political context.

A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently joined the stem-cell research efforts at the Keck School of Medicine of the University of Southern California. Their findings are being published today in an early online edition of the Proceedings of the National Academy of Sciences.

At first glance, one might think Northeastern University junior Tanya Cashorali was bent on outshining the competition. At only 21-years-old, her achievements include three co-op jobs with top cancer scientists, one grant-funded study on tumor development, and numerous presentations to world-renowned doctors. But this young prodigy isn’t out to beat the competition, she’s out to create more; a fleet of young women who study, teach, and conduct groundbreaking high-tech research.

Over a span of two decades, warming temperatures have caused annual losses of roughly $5 billion for major food crops, according to a new study by researchers at the Carnegie Institution and Lawrence Livermore National Laboratory.

To address the high rate of multiple births resulting from in-vitro-fertilization (IVF), researchers at Yale School of Medicine and McGill University have developed a procedure that estimates the reproductive potential of individual embryos, possibly leading to a decrease in multiple-infant births and a higher success rate in women undergoing IVF.

New non-toxic and targeted therapies for metastatic breast and ovarian cancers may now be possible, thanks to a discovery by a team of researchers at the University of British Columbia.

Over a span of two decades, warming temperatures have caused annual losses of roughly $5 billion for major food crops, according to a new study by researchers at the Carnegie Institution and Lawrence Livermore National Laboratory.

Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules. Their results provide insight into what may have been the first self-replicating molecule to arise billions of years ago on the evolutionary path toward the emergence of life.

New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer.

The study, which appears in the advance online edition of the journal Molecular and Cellular Biology, indicates that two proteins, named Timeless and Tipin, form a complex that regulates the rate at which DNA is replicated after exposure to ultraviolet radiation.