Pre-hospital treatment on the way to percutaneous coronary intervention

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Ondansetron reduces vomiting, hospital admissions in children with gastroenteritis

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University of North Carolina at Chapel Hill researchers have demonstrated that a drug called ondansetron helps reduce vomiting, the need for intravenous fluids and hospital admissions in children with acute gastroenteritis.

Gastroenteritis is an infection, often caused by a virus, that causes vomiting and diarrhea. It is often popularly called "stomach flu" and is a very common ailment in children during the winter months.

Nearly half of US adults will develop painful knee osteoarthritis by age 85: study

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Almost half of all U.S. adults and nearly two-thirds of obese adults will develop painful osteoarthritis of the knee by age 85, a study based at the University of North Carolina at Chapel Hill suggests.

The study also found that a person's lifetime risk rose as their body mass index or BMI increased, with the greatest risk found in those whose weight was normal at age 18 but were overweight or obese at 45 or older.

Researchers offer first direct proof of how osteoarthritis destroys cartilage

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A team of orthopaedic researchers has found definitive, genetic proof of how the most common form of arthritis destroys joint cartilage in nearly 21 million aging Americans, according to a study published online Sept. 2 in the Journal of Bone and Mineral Research. The findings serve as an important foundation for the design of new treatments for osteoarthritis (OA), researchers said.

Scientists use remote satellite imaging to predict outbreaks of infectious disease

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Scientists in the USA have established a way to predict outbreaks of cholera, making it easier to control. This finding could provide a model to predict and potentially control outbreaks of other important infectious diseases.

World Cancer Declaration sets ambitious targets for 2020

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A summit of more than 60 high-level policymakers, leaders and health experts have adopted a global plan aimed at tackling the growing cancer crisis in developing countries.

The plan, contained in the World Cancer Declaration, recommends a set of 11 cancer-busting targets for 2020 and outlines priority steps that need to be taken in order to meet them. It was presented Sunday at the close of the World Cancer Congress in Geneva and offered as a global template for governments and other groups to tailor as they devise their own plans to guide local efforts.

Scientists find second site for prostate cancer gene

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WINSTON-SALEM, N.C. – Scientists at Wake Forest University School of Medicine and colleagues who are studying a prostate cancer gene called HNF1B have found a second independent site within the HNF1B gene on chromosome 17 (17q12) – increasing the number of genetic variants that may contribute to risk of developing the disease.

New discovery about growth factor can be breakthrough for cancer research

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A research team at the Ludwig Institute and Uppsala University has discovered an entirely new signal path for a growth factor that is of crucial importance for the survival and growth of cancer cells. This discovery, published in today’s issue of Nature Cell Biology, opens up an entirely new landscape for research on breast and prostate cancer, among other types.

Survey: 'Tanorexia' common among university students

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PHILADELPHIA (Sept. 2, 2008) -- A new study conducted at a large university finds more than 25 percent of those surveyed reported symptoms of tanning dependence, including symptoms similar to alcohol and drug-addicted individuals. Suggestively, the study also found those with a tanning dependence tend to be more likely to be thin and smoke cigarettes than others. The study by researchers at Fox Chase Cancer Center is published in the September/October issue of the American Journal of Health Behavior.

Effects of the direct lipoprotein-associated phospholipase A2 inhibitor darapladib

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A twelve month study of treatment with darapladib concluded that, Lp-PLA2 inhibition with darapladib prevented necrotic core expansion, a key determinant of plaque vulnerability. These findings suggest that Lp-PLA2 inhibition may represent a novel therapeutic approach. In contrast, despite adherence to a high level of standard of care treatment, necrotic core continued to expand among patients receiving a placebo.