A novel concept for a biosensor of the metabolite known as lactate, combines an electron transporting polymer with lactate oxidase, which is the enzyme that specifically catalyzes the oxidation of lactate. Lactate is associated with critical medical conditions so its detection is important for healthcare.
An international team of researchers have developed a low-cost sensor made from semiconducting plastic that can be used to diagnose or monitor a wide range of health conditions, such as surgical complications or neurodegenerative diseases.
Every day the human gut works on a fine-tuned balance that ensures the retention of essential nutrients while it prevents the entrance of potential armful microbes. Contributing to this surveillance system is a specialised group of immune cells that are held back due to unknown reasons although they have many characteristics of activated cells. Now, a new study led by Marc Veldhoen, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) shows how these cells are kept under control.
Our faces can reveal a lot about us, and now scientists are revealing a lot about faces. PLOS Genetics announces a special collection of papers to highlight recent advances in our understanding of how faces form, curated by Seth Weinberg of the University of Pittsburgh, and colleagues. The collection, entitled "Craniofacial genetics: where have we been and where are we going," publishes June 22 and features research on the development of the face and skull, facial birth defects and normal facial variation.
URBANA, Ill. - Nematodes may be among the simplest animals, but scientists can't get enough of the microscopic roundworms. They have mapped the entire genome of C. elegans, the "lab rat" of nematodes, and have characterized nearly every aspect of its biology, with a particular focus on neurons. For years, it was assumed other nematodes' neurons were similar to those of C. elegans, until researchers at the University of Illinois demonstrated the vast diversity in neuronal anatomy present across species.
While Tropical Storm Bud was lashing parts of western Mexico and causing flooding that extended into the American Southwest, a tropical disturbance was spinning over the Gulf of Mexico and straddling southeastern Texas. This system sat in place for almost a week bringing extremely heavy rainfall and causing a flash flood emergency. More than 15 inches (381 mm) of rain fell in Hidalgo County, Texas between June 18 and 22.
PHILADELPHIA - Influenza A (flu A) hijacks host proteins for viral RNA splicing and blocking these interactions caused replication of the virus to slow, according to new research published in Nature Communications by Kristin W. Lynch, PhD, chair of the department of Biochemistry and Biophysics in the Perelman School of Medicine at the University of Pennsylvania, and doctoral student Matthew Thompson. Their results also suggest that infection with flu A may reduce splicing of some host genes, which could point to novel strategies for antiviral therapies.
June 22, 2018-- Administration of nitric oxide gas during and for 24 hours following heart surgery decreased the risk of patients developing acute and chronic kidney problems, a randomized, controlled trial conducted in China found.
PORTLAND, Oregon - Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body. New research, published today in the journal Nature Communications, shows that it may be possible to freeze cancer cells and kill them where they stand.
Princeton chemists have found a way to make a naturally occurring enzyme take on a new, artificial role, which has significant implications for modern chemistry, including pharmaceutical production. Their work appears in the journal Nature Chemistry.