Riluzole may prevent foggy 'old age' brain

Riluzole may prevent foggy 'old age' brain

Forgetfulness, it turns out, is all in the head. Scientists have shown fading memory and clouding judgment, the type that comes with advancing age, show up as lost and altered connections between neurons in the brain. But new experiments suggest an existing drug, known as riluzole and already on the market as a treatment for ALS, may help prevent these changes.

Survival rates higher in obese heart failure patients

Survival rates higher in obese heart failure patients

Patients who were obese before developing heart failure lived longer than normal weight patients with the same condition according to a new study in the Journal of the American College of Cardiology that examined the "obesity paradox" by following obese and non-obese heart failure patients for more than a decade.

High doses of vancomycin fuel risk of kidney damage in children - small study

Results of a small study show that hospitalized children given high-dose IV infusions of the antibiotic vancomycin to treat drug-resistant bacterial infections face an increased risk for kidney damage -- an often reversible but sometimes serious complication.

The findings published in Annals of Pharmacotherapy highlight the importance of prescribing the medication cautiously, the investigators say, and also underscore the need for newer, safer drugs to treat resistant infections.

Ebola vaccine candidate safe and equally immunogenic in Africa

Two experimental DNA vaccines to prevent Ebola virus and the closely related Marburg virus [1] are safe, and generated a similar immune response in healthy Ugandan adults as reported in healthy US adults earlier this year. The findings, from the first trial of filovirus vaccines in Africa, are published in The Lancet.

What happens to patients when cardiologists are away at national meetings?

Having some cardiologists away from the hospital attending national cardiology meetings did not appear to negatively affect Medicare patients admitted for heart conditions, according to a report published online by JAMA Internal Medicine.

Thousands of cardiologists take time off work each year to attend these meetings but how that might affect patients was unknown.

Physical violence and fluctuations of cortisol levels in women linked

A new study links physical violence against women by male partners to a disruption of a key steroid hormone that opens the door potentially to a variety of negative health effects.

The study by the University of Oregon and the Oregon Social Learning Center looked at daily fluctuations of cortisol levels in men and women. Cortisol was drawn from saliva samples of 122 couples during on-site assessments and four times a day -- upon waking up, 30 minutes later, in mid to late afternoon and at bedtime -- over four consecutive days.

Cardiorespiratory fitness improves memory in older adults

Older adults who have greater heart and lung health also have better memory recall and cognitive capabilities. The study, which appears online in the Journal of Gerontology, examines the relationship between cardiorespiratory fitness (CRF), memory and cognition in young and older adults.

Aging is associated with decline in executive function (problem solving, planning and organizing) and long-term memory for events. CRF has been associated with enhanced executive function in older adults, but the relationship with long-term memory remains unclear.

Air pollution linked to congenital defects

The health effects of air pollution are a major concern for urban populations all over the world. Children, the elderly, and people with impaired respiratory systems (such as asthmatics) tend to be especially sensitive to the impact of exposure to ozone, nitrogen dioxide, sulphur dioxide, and particulate matter.

Blocking excessive division of mitochondria reduces liver cell death in cholestasis

Hepatitis, steroids, birth control pills, alcohol, cancer, even gallstones can interfere with bile secretion, causing the fluid, which is made by the liver to help digest food, to stay in the liver, where it's toxic to cells, said Dr. Yisang Yoon, cell physiologist at the Medical College of Georgia at Georgia Regents University.

It's called cholestasis, a sometimes tough-to-treat condition that can damage or destroy the liver.

The math of how decisions 'cascade' in social networks

How do people in a social network behave? How are opinions, decisions and behaviors of individuals influenced by their online networks? Can the application of math help answer these questions?