Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections

Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections

(PHILADELPHIA) - A Penn Medicine team has found that targeted automated alerts in electronic health records significantly reduce urinary tract infections in hospital patients with urinary catheters. In addition, when the design of the alert was simplified, the rate of improvement dramatically increased.

Good news for diabetics who are sick of the finger prick

Good news for diabetics who are sick of the finger prick

New enzyme targets for selective cancer therapies

New enzyme targets for selective cancer therapies

(Edmonton) Thanks to important discoveries in basic and clinical research and technological advances, the fight against cancer has mobilized into a complex offensive spanning multiple fronts.

Work happening in a University of Alberta chemistry lab could help find new and more selective therapies for cancer. Researchers have developed a compound that targets a specific enzyme overexpressed in certain cancers—and they have tested its activity in cells from brain tumours.

High concordance between EGFR mutations from circulating-free tumor DNA and tumor tissue in non-small cell lung cancer

DENVER – Epidermal growth factor receptor (EGFR) mutations found in the circulating free tumor DNA (ctDNA) from the plasma of advanced non-small cell lung cancer (NSCLC) patients correlates well with the EGFR mutations from patient-matched tumor tissue DNA.

Study shows cognitive-behavioral coping skills training has positive effects on rheumatoid arthritis

Study shows Hera Therapeutics compound combats HPV types that cause most cervical cancer

La Jolla, CA – Research presented at the 29th Annual International Papillomavirus Conference shows that a therapy being developed by Hera Therapeutics Inc. combats three types of human papillomavirus, including the two that cause 70 percent of all cervical cancer.

Deletion predicts survival in advanced non-small cell lung cancer

DENVER – Bcl-2-like protein 11 (BIM) deletion in advanced non-small cell lung cancer (NSCLC) is associated with shorter progression free survival (PFS) in epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) or chemotherapy treated Asian patients. Also, BIM deletion independently predicts overall survival (OS) of advanced NSCLC patients.

Novel oncogenic RET mutation found in small cell lung cancer

DENVER – For the first time an oncogenic somatic mutation at amino acid 918 in the RET (rearranged during transfection) protein has been identified in small cell lung cancer (SCLC) tumors and enforced expression of this mutation within SCLC cell lines produced increased intracellular signaling and cell growth.

Kessler Foundation study of self-awareness in MS has implications for rehabilitation

From happiness to pain: Understanding serotonin's function

In a study published today (August 22nd), in the scientific journal PLoS One, researchers at the Champalimaud Neuroscience Programme establish the effect of serotonin on sensitivity to pain using a combination of advanced genetic and optical techniques.