Novel type 1 diabetes treatment shown to work on human beta cells transplanted into mice

Novel type 1 diabetes treatment shown to work on human beta cells transplanted into mice

TORONTO, Nov. 29, 2014--A chemical produced in the pancreas that prevented and even reversed Type 1 diabetes in mice had the same effect on human beta cells transplanted into mice, new research has found.

GABA, or gamma-aminobutryic acid, is an amino acid produced by the same beta cells that make and secrete insulin.

Entrepreneurs to venture capitalists: Don't be a Scrooge

Entrepreneurs to venture capitalists: Don't be a Scrooge

WACO, Texas (Nov. 25, 2014) - Note to venture capitalists: Entrepreneurs are watching to see if you're naughty or nice.

A recently published study of more than 550 decisions and responses from 144 experienced entrepreneurs reveals that "knowledge of explicit ethical or unethical behavior (by venture capitalists) profoundly shapes the entrepreneurs' willingness to partner."

Centipede's genome reveals how life evolved on our planet

Centipede's genome reveals how life evolved on our planet

Centipedes, those many-legged creatures that startle us in our homes and gardens, have been genetically sequenced for the first time. In a new study in the journal PLoS Biology, an international team of over 100 scientists today reveals how this humble arthropod's DNA gave them new insight into how life developed on our planet.

Full-day preschool linked with increased school readiness compared with part-day

Children who attended a full-day preschool program had higher scores on measures of school readiness skills (language, math, socio-emotional development, and physical health), increased attendance, and reduced chronic absences compared to children who attended part-day preschool, according to a study in the November 26 issue of JAMA.

Study examines FDA influence on design of pivotal drug studies

An examination of the potential interaction between pharmaceutical companies and the U.S. Food and Drug Administration (FDA) to discuss future studies finds that one-quarter of recent new drug approvals occurred without any meeting, and when such meetings occurred, pharmaceutical companies did not comply with one-quarter of the recommendations made by the FDA regarding study design or primary outcome, according to a study in the November 26 issue of JAMA.

Lawrence Livermore researchers develop efficient method to produce nanoporous metals

LIVERMORE, Calif. - Nanoporous metals -- foam-like materials that have some degree of air vacuum in their structure -- have a wide range of applications because of their superior qualities.

They posses a high surface area for better electron transfer, which can lead to the improved performance of an electrode in an electric double capacitor or battery. Nanoporous metals offer an increased number of available sites for the adsorption of analytes, a highly desirable feature for sensors.

Powdered measles vaccine found safe in early clinical trials

A measles vaccine made of fine dry powder and delivered with a puff of air triggered no adverse side effects in early human testing and it is likely effective, according to a paper to be published November 28 in the journal Vaccine. The paper is now available online.

In 2013, measles killed 145,700 people, most of them children, according to the World Health Organization. That's despite the fact that the conventional injectable vaccine against the measles virus is effective.

Obstructive sleep apnea treatments may reduce depressive symptoms

Treatment for obstructive sleep apnea with continuous positive airway pressure (CPAP) or mandibular advancement devices (MADs) can lead to modest improvements in depressive symptoms, according to a study published by Marcus Povitz, Carmelle Bolo, and colleagues from University of Calgary, Canada, in this week's PLOS Medicine.

International collaboration completes genome sequence of centipede

HOUSTON - (Nov. 25, 2014) - An international collaboration of scientists including Baylor College of Medicine has completed the first genome sequence of a myriapod, Strigamia maritima - a member of a group venomous centipedes that care for their eggs - and uncovered new clues about their biological evolution and unique absence of vision and circadian rhythm.

Over 100 researchers from 12 countries completed the project. They published their work online today in the journal PLOS Biology.

Blind scottish centipede unlocks clues to the origins of creepy crawlies

The arthropods are one of Earth's real success stories, with more species of arthropod than in any other animal phylum, but our knowledge of arthropod genomes has been heavily skewed towards the insects. Recent work has furnished us with the genome sequences of an arachnid and a crustacean, but the myriapods (centipedes and millipedes) have remained the one class of arthropods whose genomes are still in the dark.