Brain

Key to regulation of puberty discovered

A team of scientists from the University of Cambridge and the University of Cukurova in Turkey have taken a major step to understanding how the brain controls the onset of puberty.

The research, published in this week's Nature Genetics, identified the hormone Neurokinin B as a critical part of the control system that switches on the master regulator of human puberty. Although Neurokinin B was previously known to be present in the hypothalamus, the part of the brain that controls puberty, its key role was not previously appreciated.

A fading sense of smell may signal onset of Parkinson's disease

CHICAGO — Many individuals with Parkinson's disease are able to recall losing their sense of smell well before the onset of more commonly recognized symptoms such as tremors, impaired dexterity, speech problems, memory loss and decreased cognitive ability.

The profound effects of numbing agents

A large proteomics study on the brains of newborn mice provides more evidence that numbing drugs often used in obstetric or pediatric medicine can have profound and long-term negative effects, even after minimal exposure.

This study, appearing in the December issue of Molecular and Cellular Proteomics, highlights the delicate state of the developing nervous system and reinforces the use of caution when administering sedatives, anesthetics, and anti-convulsants to pregnant women or infants.

New MIT detector will aid dark matter search

CAMBRIDGE, Mass.--Several research projects are underway to try to detect particles that may make up the mysterious "dark matter" believed to dominate the universe's mass. But the existing detectors have a problem: They also pick up particles of ordinary matter — hurtling neutrons that masquerade as the elusive dark-matter particles the instruments are designed to find.

Inside the consumer mind: U of M brain scans reveal choice mechanism

That gorgeous sweater has your name written on it. But, those red suede pumps are calling your name too. What goes through your mind as you consider these choices? During normal economic times, you might indulge in a whole new wardrobe. But now, with considerably tighter budgets, consumers don't have the luxury of saying "It's the holidays -- I'll just buy both!" What happens in buyers' brains as they consider difficult choices? What can retailers do to make the choice process easier for consumers?

Stressed-out mice reveal role of epigenetics in behavior

Research conducted by a team in Switzerland suggests that a family of genes involved in regulating the expression of other genes in the brain is responsible for helping us deal with external inputs such as stress. Their results, appearing in the December 11 advance online version of the journal Neuron, may also give a clue to why some people are more susceptible to anxiety or depression than others.

Low-carb diets can affect dieters' cognition skills

MEDFORD/SOMERVILLE, Mass. -- A new study from the psychology department at Tufts University shows that when dieters eliminate carbohydrates from their meals, they performed more poorly on memory-based tasks than when they reduce calories, but maintain carbohydrates. When carbohydrates were reintroduced, cognition skills returned to normal.

Amputees can experience prosthetic hand as their own

[PRESS RELEASE, 11 December 2008] Scientists at Karolinska Institutet and Lund University in Sweden have succeeded in inducing people with an amputated arm to experience a prosthetic rubber hand as belonging to their own body. The results can lead to the development of a new type of touch-sensitive prosthetic hands.

UC San Diego researchers use metagene 'portraits' to reveal distinct stages of kidney formation

In the art world, the most successful portraits are often those that reveal the true essence of the subject – a subject that on canvas, at least, will never age. In the science world, researchers are relying on portraits of gene expression patterns – but, in this case, the images are helping to reveal how various tissues form.

Orangutan's spontaneous whistling opens new chapter in study of evolution of speech

Des Moines, Iowa – December 11, 2008 – Throughout history, human beings have used the whistle for everything from hailing a cab to carrying a tune. Now, an orangutan's spontaneous whistling is providing scientists at Great Ape Trust of Iowa new insights into the evolution of speech and learning.

Study shows major pain research funding decline at NIH

GLENVIEW, IL, Dec. 11, 2008 – Federal funding for pain research is declining sharply, more than 9 percent a year since 2003, according to a new study published in The Journal of Pain. Pain research, as a result, now accounts for only 0.6 percent of all grants awarded by the National Institutes of Health (NIH), despite the high prevalence of chronic pain in the U.S.

Strategic video game improves critical cognitive skills in older adults

A desire to rule the world may be a good thing if you're over 60 and worried about losing your mental faculties. A new study found that adults in their 60s and 70s can improve a number of cognitive functions by playing a strategic video game that rewards nation-building and territorial expansion.

This is the first such study of older adults, and it is the first to find such pronounced effects on cognitive skills not directly related to the skills learned in the video game, said University of Illinois psychology professor Arthur Kramer, an author on the study.

Success of anti-meth ads questioned by study

Washington, DC, December 11, 2008-- An independent review investigating the effectiveness of a publicly funded graphic anti-methamphetamine advertising campaign has found that the campaign has been associated with many negative outcomes. The review was published in the December issue of Prevention Science, a peer reviewed journal of the Society for Prevention Research (SPR).

Exercise suppresses appetite by affecting appetite hormones

BETHESDA, Md. (Dec. 11, 2008) − A vigorous 60-minute workout on a treadmill affects the release of two key appetite hormones, ghrelin and peptide YY, while 90 minutes of weight lifting affects the level of only ghrelin, according to a new study. Taken together, the research shows that aerobic exercise is better at suppressing appetite than non-aerobic exercise and provides a possible explanation for how that happens.

If MRI shows signs of MS, will the disease develop?

ST. PAUL, Minn. – With more and more people having brain MRIs for various reasons, doctors are finding people whose scans show signs of multiple sclerosis (MS) even though they have no symptoms of the disease. A new study published in the December 10, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology, found that a third of these people developed MS within an average of about five years.