Brain

Hormones increase frequency of inherited form of migraine in women

Familial hemiplegic migraine (FHM) is an inherited form of severe migraine that is accompanied by visual disturbances known as aura. As with other types of migraine, it affects women more frequently than men. Most cases of FHM are caused by mutations in the CACNA1A gene, but whether these lead to spreading depression, the event in the brain that suppresses nerve cell activity and that has been linked to nongenetic forms of migraine with aura, has not been determined.

Immune cells contribute to the development of Parkinson's disease

Parkinson disease is a neurodegenerative disorder that impairs movement, balance, speech, and other functions. It is characterized by the loss of nerves in the brain that produce a substance known as dopamine. Although the loss of dopamine-containing nerves is accompanied by accumulation of immune cells known as T cells, these accumulating T cells were not thought to have a role in the development of disease. However, Stéphane Hunot, Etienne C.

Shape changes in aroma-producing molecules determine the fragrances we detect

NEW YORK, December 22, 2008 - Shakespeare wrote "a rose by any other namewould smell as sweet." But would it if the molecules that generate itsfragrance were to change their shape?

Blind man walking: With no visual awareness, man navigates obstacle course flawlessly

Researchers have demonstrated for the first time that people can successfully navigate an obstacle course even after brain damage has left them with no awareness of the ability to see and no activity in the visual cortex, a region of the brain's cortex that is primarily responsible for processing visual inputs.

New research lights up chronic bacterial infection inside bone

December 22, 2008, Cambridge, UK – A new report demonstrates how a sensitive imaging technique gives scientists the upper hand in seeking out bacteria in chronic infections.

The effect of parental education on the heritability of children's reading disability

Parental education is a strong predictor of socioeconomic status and children's educational environment. Nevertheless, some children continue to experience reading failure in spite of high parental education and support for learning to read.

Premature babies have altered sensory responses in later life

Premature infants who need intensive care or surgery are less sensitive to thermal (hot and cold) sensations later in life, according to research conducted at UCL (University College London). The study, published in the journal Pain, suggests that pain and injury related to major medical interventions in early development may alter how children respond to painful stimuli much later in life.

Hebrew University scientists reveal mechanism that triggers differentiation of embryo cells

Jerusalem, December 21, 2008 –The mechanism whereby embryonic cells stop being flexible and turn into more mature cells that can develop into specific tissues has been discovered by scientists at the Hebrew University of Jerusalem. The discovery has significant consequences towards furthering research that will eventually make possible medical cell replacement therapy based on the use of embryonic cells.

Yeast mimics severity of mutations leading to fatal childhood illness

December 22, 2008, Cambridge, UK – Scientists report that human gene mutations expressed in yeast cells can predict the severity of Batten Disease, a fatal nervous system disorder that begins during childhood. The new study published in Disease Models & Mechanisms (DMM), dmm.biologists.org, describes how the extent of changes in mutated cells paralleled the severity of symptoms seen in humans.

MSU research: Genes may influence popularity

EAST LANSING, Mich. — A groundbreaking study of popularity by a Michigan State University scientist has found that genes elicit not only specific behaviors but also the social consequences of those behaviors.

According to the investigation by behavioral geneticist S. Alexandra Burt, male college students who had a gene associated with rule-breaking behavior were rated most popular by a group of previously unacquainted peers.

New 'smart' materials for the brain

Research done by scientists in Italy and Switzerland has shown that carbon nanotubes may be the ideal "smart" brain material. Their results, published December 21 in the advance online edition of the journal Nature Nanotechnology, are a promising step forward in the search to find ways to "bypass" faulty brain wiring.

Two cardiovascular proteins pose a double whammy in Alzheimer's

Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease. Not only do the proteins lessen blood flow in the brain, but they also reduce the rate at which the brain is able to remove amyloid beta, the protein that builds up in toxic quantities in the brains of patients with the disease.

Snails and humans use same genes to tell right from left

Berkeley -- Biologists have tracked down genes that control the handedness of snail shells, and they turn out to be similar to the genes used by humans to set up the left and right sides of the body.

Vulnerability to post-traumatic stress disorder runs in families, study shows

Earthquakes have aftershocks — not just the geological kind but the mental kind as well. Just like veterans of war, earthquake survivors can experience post-traumatic stress disorder, depression and anxiety.

In 1988, a massive earthquake in Armenia killed 17,000 people and destroyed nearly half the town of Gumri. Now, in the first multigenerational study of its kind, UCLA researchers studying survivors of that catastrophe have discovered that vulnerability to PTSD, anxiety and depression runs in families.

M. D. Anderson neurosurgeon, Amy Heimberger, M.D., receives presidential award

HOUSTON - Amy Heimberger, M.D., associate professor of neurosurgery at The University of Texas M. D. Anderson Cancer Center has received a Presidential Early Career Award for Scientists and Engineers (PECASE), in recognition for her research on the central nervous system's immune biology, tumor evasion of immune detection and immunotherapeutic approaches for patients with malignant gliomas.