Brain

CHAPEL HILL, N.C. – Researchers at the University of North Carolina at Chapel Hill have pinpointed a crucial function for a key player in the development of the nervous system. They found that this player – a protein called Erk – is necessary for nerve fibers to be wrapped with an insulating substance called myelin, which allows messages to be sent from the brain to the peripheral limbs and back again.

AUSTIN, Texas—Men are more than twice as likely to continue dating a girlfriend who has cheated on them with another woman than one who has cheated with another man, according to new research from a University of Texas at Austin psychologist.

Women show the opposite pattern. They are more likely to continue dating a man who has had a heterosexual affair than one who has had a homosexual affair.

Philadelphia, Pa, 27 January 2010 - The growing numbers of new cases of substance abuse disorders are perplexing. After all, the course of drug addiction so often ends badly. The negative consequences of drug abuse appear regularly on TV, from stories of celebrities behaving in socially inappropriate and self-destructive ways while intoxicated to dramatization of the rigors of drug withdrawal on "Intervention" and other reality shows.

A naturally occurring growth factor significantly boosted retention and prevented forgetting of a fear memory when injected into rats' memory circuitry during time-limited windows when memories become fragile and changeable. In the study funded by the National Institutes of Health, animals treated with insulin-like growth factor (IGF-II) excelled at remembering to avoid a location where they had previously experienced a mild shock.

Researchers from Mount Sinai School of Medicine have identified a therapy that may enhance memory and prevent the loss of long-term memory. The research is published in the January 27th issue of Nature.

Led by Cristina Alberini, PhD, Professor of Neuroscience at Mount Sinai, the research team evaluated how a protein called insulin-like growth factor II (IGF-II), a gene expressed during brain development that declines with aging, impacts memory formation and retention.

A new study provides insight into how stress impacts the brain and may help to explain why some individuals are predisposed to depression when they experience chronic stress. The research, published by Cell Press in the January 27 issue of the journal Neuron, reveals complex molecular mechanisms associated with chronic stress and may help to guide new treatment strategies for depression.

A new study takes a close look at the brain of the migratory monarch butterfly to better understand how these remarkable insects use an internal compass and skylight cues to navigate from eastern North America to Mexico each fall. The research, published by Cell Press in the January 27 issue of the journal Neuron, provides key insights into how ambiguous sensory signals can be integrated in the brain to guide complex navigation.

LA JOLLA, CA – January 24, 2010 – Embargoed by the journal Neuron until January 26, 2010, noon, Eastern time – Connected highways of nerve cells carry information to and from different areas of the brain and the rest of the nervous system. Scientists are trying to draw a complete atlas of these connections—sometimes referred to as the "connectome"—to gain a better understanding of how the brain functions in health and disease.

Misaligned research, medical challenges and harsh economics are thwarting efforts to slow the destructive course of Alzheimer's disease in the United States, according to a trio of nationally regarded Alzheimer's researchers writing a "Perspective" in Thursday's (Jan. 27) issue of the journal Neuron.

The foremost obstacle is that the most promising preventive strategies are being tested in patients firmly in the grip of Alzheimer's disease — the ones least likely to be helped.

A new target for the prevention of adverse immune responses identified as factors in the development of Alzheimer's disease (AD) has been discovered by researchers at the University of South Florida's Department of Psychiatry and the Center of Excellence for Aging and Brain Repair.

Their findings are published online in the Journal of Neuroscience (http://www.jneurosci.org/).

CHICAGO (January 26) – Scientists at The Rehabilitation Institute of Chicago (RIC), designated the "#1 Rehabilitation Hospital in America" by U.S. News & World Report since 1991, report that, thanks to improvements in technology and data analysis, our understanding of the functional principles that guide the development and operation of the brain could improve drastically in the next few years. The advances could herald a neuroscientific revolution, much as increasing processor speeds paved the way for the computing revolution of the last half century.

Scientists in the Hotchkiss Brain Institute at the Faculty of Medicine, University of Calgary, have discovered a new mechanism that nerve cells (neurons) use to fine-tune their electrical output. The exciting discovery, published this week in the prestigious journal Nature Neuroscience, provides new insights about how the activity of the nervous system is regulated at the cellular level.

WASHINGTON – Hands-on safety training for workers in highly hazardous jobs is most effective at improving safe work behavior, according to psychologists who analyzed close to 40 years of research. However, less engaging training can be just as effective in preparing workers to avoid accidents when jobs are less dangerous.