Body

PORTAND, Ore. – Scientists at Oregon Health & Science University and the Oregon National Primate Research Center (ONPRC) have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body. It is believed that stem cell therapies hold the promise of replacing cells damaged through injury or illness. Diseases or conditions that might be treated through stem cell therapy include Parkinson's disease, multiple sclerosis, cardiac disease and spinal cord injuries.

This news release is available in German.

Photographers know the problem all too well: with the naked eye, you can see which branch a bird is sitting on, but spotting the bird in the blur of branches through the telephoto lens for high-magnification images requires considerable skill. It is a similar story for researchers who are looking to study proteins, the active biomolecules of cells.

PITTSBURGH, May 15, 2013 – Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in the Journal of Clinical Investigation. Their study, sponsored by the National Institutes of Health, suggests a different paradigm is needed to develop better anti-rejection therapies.

"When Neta showed me the data, I was absolutely amazed, I couldn't believe it," Professor Cowman said. "We repeated the experiments many times in many different ways before I really started to believe that these parasites were signalling to each other and communicating. But we came to appreciate why the malaria parasite really needs this mechanism – it needs to know how many other parasites are in the human to sense when is the right time to activate into sexual forms that give it the best chance of being transmitted back to the mosquito."

SALT LAKE CITY – Research conducted by the Pelvic Floor Disorders Network, an initiative funded by the National Institutes of Health, has revealed that the long-term success rates of a surgery to treat pelvic organ prolapse are lower than expected. Nearly one-third of women develop anatomic or symptomatic treatment failure within five years of undergoing sacrocolpopexy for pelvic organ prolapse, according to a study published in the May 15 issue of JAMA.

University of Alberta researchers have developed guidelines being used by foresters and the timber industry to get a jump on climate change when planting trees.

Maps developed by Laura Gray, a post-doctoral fellow in the Department of Renewable Resources, provide projections of climatically suitable habitat for tree species based on climate predictions for the 2020s, 2050s and 2080s.

A class of water-loving, jelly-like materials with uses ranges ranging from the mundane, such as superabsorbent diaper liners, to the sophisticated, such as soft contact lenses, could be tapped for a new line of serious work: testing the biological effects of nanoparticles now being eyed for a large variety of uses.

Women in their 40s continue to undergo routine breast cancer screenings despite national guidelines recommending otherwise, according to new Johns Hopkins research.

In 2009, the U.S. Preventive Services Task Force (USPSTF) sifted through the evidence and recommended that while women ages 50-74 should continue to undergo mammograms every two years, those between the ages of 40 and 49 without a family history of breast cancer should discuss the risks and benefits of routine screening mammography with their physicians to make individual decisions.

ATLANTA - In the past, researchers have sought to determine the geographic distribution of many life-threatening conditions, including stroke and cardiac arrest. Now, researchers at the Perelman School of Medicine at the University of Pennsylvania have created the first U.S. map that pinpoints hotspots for infection and severe sepsis related-deaths – with notable clusters located in the Midwest, mid-Atlantic, and the South. The research is a critical first step in helping to determine which areas of the country require vital public health resources to fight these deadly diseases.

Water mites of the family Torrenticolidae are tiny, heavily sclerotized and crawling water creatures presently known from all continents except Antarctica. More than 400 species are described so far but this is expected to be only a minor pars of their diversity, especially in the tropical areas where the family is most species abundant. Until recently only one species was known from South Korea, and five from the Russian Far East.

DARIEN, IL – A new study found a relationship between sleep duration and suicidal thoughts in people with insomnia.

Results show that every one-hour increase in sleep duration was associated with a 72 percent decrease in the likelihood of moderate or high suicide risk, in comparison with low risk. Data were adjusted for age, gender, race/ethnicity, education and age of onset of sleep difficulties.

New technology offers the promise of reducing billions of dollars of losses that occur each year from the silent, invisible killer of fruits, vegetables and cut flowers — a gas whose effects are familiar to everyone who has seen bananas and other fruit ripen too quickly and rot. That's the conclusion of an article in the ACS journal Chemical Reviews.

Having too much body fat makes arteries become stiff after middle age, a new study has revealed.

In young people, blood vessels appear to be able to compensate for the effects of obesity. But after middle age, this adaptability is lost, and arteries become progressively stiffer as body fat rises – potentially increasing the risk of dying from cardiovascular disease.

How cells regulate their own function by "accelerating and braking" is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. In a study published by Nature Communications 14 May, researchers at Uppsala and Umeå universities show a model of how cells' regulatory systems work.

San Francisco, Calif. May 15, 2013 – Considered the "silent killer," high blood pressure affects approximately one billion people worldwide, including one in three adults in the United States. From May 15 – 18, 2013, members of the medical community from across the globe gather at the 28th Annual Scientific Meeting of the American Society of Hypertension (ASH) in San Francisco to discuss the epidemic. During the conference, more than 200 new studies about hypertension will be shared, with the goal of increasing the understanding of hypertension and one day curing it altogether.